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Female Infertility
Female infertility refers to infertility in women, which is the inability to Fertilisation, conceive after sexual intercourse. It affects an estimated 48 million women, globally. Female infertility varies widely by region. The highest rates of female infertility are found in Eastern Europe and South Central Asia, followed by South Asia, Sub-Saharan Africa, and Middle East and North Africa. Female infertility rates are lowest in East Asia and Latin America. Fertility is affected by a variety of factors, including hormone, hormones, nutritional status, disease, and malformations of the uterus. Infertility affects women from around the world, and the social stigmas affecting infertile women may vary from region to region. Cause Causes or factors of female infertility can basically be classified regarding whether they are Acquired disorder, acquired or genetic, or strictly by location. Although factors of female infertility can be classified as either acquired or genetic, female i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subfertility
In biology, infertility is the inability of a male and female organism to Sexual reproduction, reproduce. It is usually not the natural state of a healthy organism that has reached sexual maturity, so children who have not undergone puberty, which is the body's start of fertility, reproductive capacity, are excluded. It is also a normal state in women after menopause. In humans, ''infertility'' is defined as the inability to become pregnant after at least one year of unprotected and regular sexual intercourse involving a male and female partner. There are many causes of infertility, including some that Assisted reproductive technology, medical intervention can treat. Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem with infertility. Many more couples, however, experience involuntary childlessness for at least one year, with estimates ranging from 12% to 28%. Male infertility is responsible for 20–30% of infert ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature And Nurture
Nature versus nurture is a long-standing debate in biology and society about the relative influence on human beings of their genetic inheritance (nature) and the environmental conditions of their development ( nurture). The alliterative expression "nature and nurture" in English has been in use since at least the Elizabethan period and goes back to medieval French. The complementary combination of the two concepts is an ancient concept (). Nature is what people think of as pre-wiring and is influenced by genetic inheritance and other biological factors. Nurture is generally taken as the influence of external factors after conception e.g. the product of exposure, experience and learning on an individual. The phrase in its modern sense was popularized by the Victorian polymath Francis Galton, the modern founder of eugenics and behavioral genetics when he was discussing the influence of heredity and environment on social advancement. Galton was influenced by ''On the Origin of Sp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canada
Canada is a country in North America. Its Provinces and territories of Canada, ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, making it the world's List of countries and dependencies by area, second-largest country by total area, with the List of countries by length of coastline, world's longest coastline. Its Canada–United States border, border with the United States is the world's longest international land border. The country is characterized by a wide range of both Temperature in Canada, meteorologic and Geography of Canada, geological regions. With Population of Canada, a population of over 41million people, it has widely varying population densities, with the majority residing in List of the largest population centres in Canada, urban areas and large areas of the country being sparsely populated. Canada's capital is Ottawa and List of census metropolitan areas and agglomerations in Canada, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Menarche
Menarche ( ; ) is the first menstrual cycle, or first menstruation, menstrual bleeding, in female humans. From both social and medical perspectives, it is often considered the central event of female puberty, as it signals the possibility of fertility. Girls experience menarche at different ages, but the most common age is 12. Having menarche occur between the ages of 9–14 in the West is considered normal.US National Health Statistics Report September 2020 The timing of menarche is influenced by female biology, as well as Genetics, genetic, environmental factors, and nutritional factors. The mean age of menarche has declined over the last century, but the magnitude of the decline and the factors responsible remain subjects of contention. The worldwide average age of menarche is very difficult to estimate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Environmental Toxins In Pregnancy
Environmental toxicants and fetal development is the impact of different toxic substances from the environment on the development of the fetus. This article deals with potential adverse effects of environmental toxicants on the prenatal development of both the embryo or fetus, as well as pregnancy complications. The human embryo or fetus is relatively susceptible to impact from adverse conditions within the mother's environment. Substandard fetal conditions often cause various degrees of developmental delays, both physical and mental, for the growing baby. Although some variables do occur as a result of genetic conditions pertaining to the father, a great many are directly brought about from environmental toxins that the mother is exposed to. Various toxins pose a significant hazard to fetuses during development. A 2011 study found that virtually all US pregnant women carry multiple chemicals, including some banned since the 1970s, in their bodies. Researchers detected polychlorina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication ( translesion synthesis). Mutations may also result from substitution, insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ult ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society For Reproductive Medicine
The American Society for Reproductive Medicine (ASRM) is a nonprofit, multidisciplinary organization for advancement of the science and practice of reproductive medicine. The society has its headquarters in Washington, D.C., and its administrative office in Birmingham, Alabama. An associated special interest group, the Society for Assisted Reproductive Technology (SART), maintains a national registry for tracking IVF attempts and outcomes. History and activities Founded in 1944 by a small group of fertility experts who met in Chicago, the initial name was the American Society for the Study of Sterility, changed in 1965 to American Fertility Society (AFS). The current name, American Society for Reproductive Medicine, was adopted in 1994. In 2018, ASRM created its own research institute. In 2019, it moved its headquarters to Washington, D.C., from Birmingham, Alabama. Though primarily an American organization, it had members from over 100 countries as of 2020. The society hosts ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PCOS
Polycystic ovary syndrome, or polycystic ovarian syndrome, (PCOS) is the most common endocrine disorder in women of reproductive age. The name is a misnomer, as not all women with this condition develop cysts on their ovaries. The name originated from the observation of cysts which form on the ovaries of some women with this condition. However, this is not a universal symptom and is not the underlying cause of the disorder. The primary characteristics of PCOS include hyperandrogenism, anovulation, insulin resistance, and neuroendocrine disruption. Women may also experience irregular menstrual periods, heavy periods, excess hair, acne, pelvic pain, difficulty getting pregnant, and patches of darker skin. Beyond its reproductive implications, PCOS is increasingly recognized as a multifactorial metabolic condition with significant long-term health consequences, including an elevated risk of cardiovascular disease and type 2 diabetes. A review of international evidence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pituitary
The pituitary gland or hypophysis is an endocrine gland in vertebrates. In humans, the pituitary gland is located at the base of the brain, protruding off the bottom of the hypothalamus. The pituitary gland and the hypothalamus control much of the body's endocrine system. It is seated in part of the sella turcica a depression in the sphenoid bone, known as the hypophyseal fossa. The human pituitary gland is oval shaped, about 1 cm in diameter, in weight on average, and about the size of a kidney bean. Digital version. There are two main lobes of the pituitary, an anterior lobe, and a posterior lobe joined and separated by a small intermediate lobe. The anterior lobe (adenohypophysis) is the glandular part that produces and secretes several hormones. The posterior lobe (neurohypophysis) secretes neurohypophysial hormones produced in the hypothalamus. Both lobes have different origins and they are both controlled by the hypothalamus. Hormones secreted from the pituitary g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypothalamus
The hypothalamus (: hypothalami; ) is a small part of the vertebrate brain that contains a number of nucleus (neuroanatomy), nuclei with a variety of functions. One of the most important functions is to link the nervous system to the endocrine system via the pituitary gland. The hypothalamus is located below the thalamus and is part of the limbic system. It forms the Basal (anatomy), basal part of the diencephalon. All vertebrate brains contain a hypothalamus. In humans, it is about the size of an Almond#Nut, almond. The hypothalamus has the function of regulating certain metabolic biological process, processes and other activities of the autonomic nervous system. It biosynthesis, synthesizes and secretes certain neurohormones, called releasing hormones or hypothalamic hormones, and these in turn stimulate or inhibit the secretion of hormones from the pituitary gland. The hypothalamus controls thermoregulation, body temperature, hunger (physiology), hunger, important aspects o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GnRH
Gonadotropin-releasing hormone (GnRH) is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is a tropic peptide hormone synthesized and released from GnRH neurons within the hypothalamus. GnRH is inhibited by testosterone. The peptide belongs to gonadotropin-releasing hormone family. It constitutes the initial step in the hypothalamic–pituitary–gonadal axis. Structure The identity of GnRH was clarified by the 1977 Nobel Laureates Roger Guillemin and Andrew V. Schally: pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 As is standard for peptide representation, the sequence is given from amino terminus to carboxyl terminus; also standard is omission of the designation of chirality, with assumption that all amino acids are in their L- form. The abbreviations are the standard abbreviations for the corresponding proteinogenic amino acids, except for ''pyroGlu'', which refers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
