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Fed-batch
Fed-batch culture is, in the broadest sense, defined as an operational technique in biotechnological processes where one or more nutrients (substrates) are fed (supplied) to the bioreactor during cultivation and in which the product(s) remain in the bioreactor until the end of the run.Tsuneo Yamanè, Shoichi Shimizu: Fed-batch Techniques in Microbial Processes. Advances in Biochem Eng./Biotechnol 1984, 30:147-194. An alternative description of the method is that of a culture in which "a base medium supports initial cell culture and a feed medium is added to prevent nutrient depletion". It is also a type of semi-batch culture. In some cases, all the nutrients are fed into the bioreactor. The advantage of the fed-batch culture is that one can control concentration of fed-substrate in the culture liquid at arbitrarily desired levels (in many cases, at low levels). Generally speaking, fed-batch culture is superior to conventional batch culture when controlling concentrations of a n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Fed Batch Reactor FSTR
Fed, The Fed, Feds, or FED may refer to: People * Feds, a List of police-related slang terms#F, slang term for a police officer in several countries Persons * Andrey A. Fedorov (1908–1987), Soviet Russian biologist, author abbreviation * John Fedorowicz (born 1958), American International Grandmaster of chess also called "The Fed". * Roger Federer (born 1981), Swiss tennis player sometimes referred to as "Fed". Places * Fort Edward station (Amtrak code FED), New York, United States * FEDS Xinyi A13, Taipei, Taiwan; a shopping mall * FEDS Zhubei, Zhubei, Hsinchu, Taiwan; a shopping mall Arts, entertainment, media * Fed (album), ''Fed'' (album), a 2002 album by American musician Liam Hayes * "Fed" (song), a song by Liam Hayes, the title track off the eponymous 2002 album Fed (album), ''Fed'' (album) * Feds (film), ''Feds'' (film), a 1988 U.S. cop-comedy film Television * Fed (Law & Order), "Fed" (''Law & Order''), episode of the television series ''Law & Order'' * Feds (TV se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Escherichia Coli
''Escherichia coli'' ( )Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. is a gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus '' Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are part of the normal microbiota of the gut, where they constitute about 0.1%, along with other facultative anaerobes. These bacteria are mostly harmless or even beneficial to humans. For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by harmful pathogenic bacteria. These mutually beneficial relationships between ''E. coli'' and humans are a type of mutualistic biological relationship—where both the humans and the ''E. coli'' are benefitting each other. ''E. coli'' is expelled into the environment within fecal matter. The bacterium grows massi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Alvin W
''Alvin'' (DSV-2) is a crewed deep-ocean research submersible owned by the United States Navy and operated by the Woods Hole Oceanographic Institution (WHOI) of Woods Hole, Massachusetts. The original vehicle was built by General Mills' Electronics Group in Minneapolis, Minnesota. Named to honor the prime mover and creative inspiration for the vehicle, Allyn Vine, ''Alvin'' was commissioned on June 5, 1964. The submersible is launched from the deep submergence support vessel , which is also owned by the U.S. Navy and operated by WHOI. The submersible has made more than 5,200 dives, carrying two scientists and a pilot, observing the lifeforms that must cope with super-pressures and move about in total darkness, as well as exploring the wreck of ''Titanic''. Research conducted by ''Alvin'' has been featured in nearly 2,000 scientific papers. Design ''Alvin'' was designed as a replacement for bathyscaphes and other less maneuverable oceanographic vehicles. Its more nimble desig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Catabolite Repression
Carbon catabolite repression, or simply catabolite repression, is an important part of global control system of various bacteria and other microorganisms. Catabolite repression allows microorganisms to adapt quickly to a preferred (rapidly metabolizable) carbon and energy source first. This is usually achieved through inhibition of synthesis of enzymes involved in catabolism of carbon sources other than the preferred one. The catabolite repression was first shown to be initiated by glucose and therefore sometimes referred to as the glucose effect. However, the term "glucose effect" is actually a misnomer since other carbon sources are known to induce catabolite repression. It was discovered by Frédéric Diénert in 1900. Jacques Monod provides a bibliography of pre-1940 literature. ''Escherichia coli'' Catabolite repression was extensively studied in ''Escherichia coli''. ''E. coli'' grows faster on glucose than on any other carbon source. For example, if ''E. coli'' is placed o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Fed Batch Principle
Fed, The Fed, Feds, or FED may refer to: People * Feds, a slang term for a police officer in several countries Persons * Andrey A. Fedorov (1908–1987), Soviet Russian biologist, author abbreviation * John Fedorowicz (born 1958), American International Grandmaster of chess also called "The Fed". * Roger Federer (born 1981), Swiss tennis player sometimes referred to as "Fed". Places * Fort Edward station (Amtrak code FED), New York, United States * FEDS Xinyi A13, Taipei, Taiwan; a shopping mall * FEDS Zhubei, Zhubei, Hsinchu, Taiwan; a shopping mall Arts, entertainment, media * ''Fed'' (album), a 2002 album by American musician Liam Hayes * "Fed" (song), a song by Liam Hayes, the title track off the eponymous 2002 album ''Fed'' (album) * ''Feds'' (film), a 1988 U.S. cop-comedy film Television * "Fed" (''Law & Order''), episode of the television series ''Law & Order'' * ''Feds'' (TV series), a 1997 U.S. legal drama TV show * ''The Feds'' (miniseries), a 1990s Aust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Saccharomyces Cerevisiae
''Saccharomyces cerevisiae'' () (brewer's yeast or baker's yeast) is a species of yeast (single-celled fungal microorganisms). The species has been instrumental in winemaking, baking, and brewing since ancient times. It is believed to have been originally isolated from the skin of grapes. It is one of the most intensively studied eukaryotic model organisms in molecular and cell biology, much like '' Escherichia coli'' as the model bacterium. It is the microorganism which causes many common types of fermentation. ''S. cerevisiae'' cells are round to ovoid, 5–10 μm in diameter. It reproduces by budding. Many proteins important in human biology were first discovered by studying their homologs in yeast; these proteins include cell cycle proteins, signaling proteins, and protein-processing enzymes. ''S. cerevisiae'' is currently the only yeast cell known to have Berkeley bodies present, which are involved in particular secretory pathways. Antibodies again ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Ethanol
Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound with the chemical formula . It is an Alcohol (chemistry), alcohol, with its formula also written as , or EtOH, where Et is the pseudoelement symbol for ethyl group, ethyl. Ethanol is a Volatility (chemistry), volatile, flammable, colorless liquid with a characteristic wine-like odor and pungent taste. As a psychoactive depressant, it is the active ingredient in alcoholic beverages, and the second most consumed drug globally behind caffeine. Ethanol is naturally produced by the fermentation process of sugars by yeasts or via petrochemical processes such as ethylene hydration. Historically it was used as a general anesthetic, and has modern medical applications as an antiseptic, disinfectant, solvent for some medications, and antidote for methanol poisoning and ethylene glycol poisoning. It is used as a chemical solvent and in the Chemical synthesis, synthesis of orga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Lactic Acid
Lactic acid is an organic acid. It has the molecular formula C3H6O3. It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as well as natural sources. Lactic acid is an alpha-hydroxy acid (AHA) due to the presence of a hydroxyl group adjacent to the carboxyl group. It is used as a synthetic intermediate in many organic synthesis industries and in various biochemical industries. The conjugate base of lactic acid is called lactate (or the lactate anion). The name of the derived acyl group is lactoyl. In solution, it can ionize by a loss of a proton to produce the lactate ion . Compared to acetic acid, its p''K'' is 1 unit less, meaning lactic acid is ten times more acidic than acetic acid. This higher acidity is the consequence of the intramolecular hydrogen bonding between the α-hydroxyl and the carboxylate group. Lactic acid is chiral, consisting of two en ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Acetate
An acetate is a salt formed by the combination of acetic acid with a base (e.g. alkaline, earthy, metallic, nonmetallic, or radical base). "Acetate" also describes the conjugate base or ion (specifically, the negatively charged ion called an anion) typically found in aqueous solution and written with the chemical formula . The neutral molecules formed by the combination of the acetate ion and a ''positive'' ion (called a cation) are also commonly called "acetates" (hence, ''acetate of lead'', ''acetate of aluminium'', etc.). The simplest of these is hydrogen acetate (called acetic acid) with corresponding salts, esters, and the polyatomic anion , or . Most of the approximately 5 million tonnes of acetic acid produced annually in industry are used in the production of acetates, which usually take the form of polymers. In nature, acetate is the most common building block for biosynthesis. Nomenclature and common formula When part of a salt, the formula of the acetate i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Biotechnological
Biotechnology is a multidisciplinary field that involves the integration of natural sciences and engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists in the field are known as biotechnologists. The term ''biotechnology'' was first used by Károly Ereky in 1919 to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and consequently, create n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Open Reading Frame
In molecular biology, reading frames are defined as spans of DNA sequence between the start and stop codons. Usually, this is considered within a studied region of a prokaryotic DNA sequence, where only one of the six possible reading frames will be "open" (the "reading", however, refers to the RNA produced by transcription of the DNA and its subsequent interaction with the ribosome in translation). Such an open reading frame (ORF) may contain a start codon (usually AUG in terms of RNA) and by definition cannot extend beyond a stop codon (usually UAA, UAG or UGA in RNA). That start codon (not necessarily the first) indicates where translation may start. The transcription termination site is located after the ORF, beyond the translation stop codon. If transcription were to cease before the stop codon, an incomplete protein would be made during translation. In eukaryotic genes with multiple exons, introns are removed and exons are then joined together after transcription to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Catabolite Repression
Carbon catabolite repression, or simply catabolite repression, is an important part of global control system of various bacteria and other microorganisms. Catabolite repression allows microorganisms to adapt quickly to a preferred (rapidly metabolizable) carbon and energy source first. This is usually achieved through inhibition of synthesis of enzymes involved in catabolism of carbon sources other than the preferred one. The catabolite repression was first shown to be initiated by glucose and therefore sometimes referred to as the glucose effect. However, the term "glucose effect" is actually a misnomer since other carbon sources are known to induce catabolite repression. It was discovered by Frédéric Diénert in 1900. Jacques Monod provides a bibliography of pre-1940 literature. ''Escherichia coli'' Catabolite repression was extensively studied in ''Escherichia coli''. ''E. coli'' grows faster on glucose than on any other carbon source. For example, if ''E. coli'' is placed o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |