Einar Lundsgaard
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Einar Lundsgaard
Einar Lundsgaard (12 February 1899 – 18 December 1968) was a Danish professor of physiology at the University of Copenhagen (1934–1967). He was among the first to demonstrate that muscles contractions drew their energy from dephosphorylization of creatine phosphate when glycolysis was inhibited using iodoacetate. Life and work Lundsgaard was born in Copenhagen where his father was a physician who came from the Gundelach family of lawyers and civil servants His father received a gold medal for his work on prostatic hypertrophy from the University of Copenhagen. His mother came from the Salomon family. At school he played guitar as a hobby. In 1917 he completed school and entered medical studies. He completed studies in 1923 and worked at the institute of medical physiology under Valdemar Henriques. He received a doctorate in 1929. His major finding was on muscle contraction when glycolysis was blocked by mono-iodoacetate. He found that energy was drawn from the phosphate bon ...
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University Of Copenhagen
The University of Copenhagen (, KU) is a public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia, after Uppsala University. The University of Copenhagen consists of six different Faculty (division), faculties, with teaching taking place in its four distinct campuses, all situated in Copenhagen. The university operates 36 different departments and 122 separate research centres in Copenhagen, as well as a number of museums and botanical gardens in and outside the Danish capital. The University of Copenhagen also owns and operates multiple research stations around Denmark, with two additional ones located in Greenland. Additionally, University of Copenhagen Faculty of Health and Medical Sciences, The Faculty of Health and Medical Sciences and the public hospitals of the Capital Region of Denmark, Capital and Region Zealand, Zealand Region of Denmark constitute the ...
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Dephosphorylation
In biochemistry, dephosphorylation is the removal of a phosphate () group from an organic compound by hydrolysis. It is a reversible post-translational modification. Dephosphorylation and its counterpart, phosphorylation, activate and deactivate enzymes by detaching or attaching phosphoric esters and anhydrides. A notable occurrence of dephosphorylation is the conversion of Adenosine triphosphate, ATP to Adenosine diphosphate, ADP and inorganic phosphate. Dephosphorylation employs a type of hydrolytic enzyme, or hydrolase, which cleaves ester bonds. The prominent hydrolase subclass used in dephosphorylation is phosphatase, which removes phosphate groups by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl (–OH) group. The reversible phosphorylation-dephosphorylation reaction occurs in every physiological process, making proper function of protein phosphatases necessary for organism viability. Because protein dephosphorylation is a k ...
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Phosphate
Phosphates are the naturally occurring form of the element phosphorus. In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. It most commonly means orthophosphate, a derivative of orthophosphoric acid, phosphoric acid . The phosphate or orthophosphate ion is derived from phosphoric acid by the removal of three protons . Removal of one proton gives the dihydrogen phosphate ion while removal of two protons gives the hydrogen phosphate ion . These names are also used for salts of those anions, such as ammonium dihydrogen phosphate and trisodium phosphate. File:3-phosphoric-acid-3D-balls.png, Phosphoricacid File:2-dihydrogenphosphate-3D-balls.png, Dihydrogenphosphate File:1-hydrogenphosphate-3D-balls.png, Hydrogenphosphate File:0-phosphate-3D-balls.png, Phosphate or orthophosphate In organic chemistry, phosphate or orthophosphate is an organophosphate, an ester of orthophosphoric acid of the form where one ...
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Glycolysis
Glycolysis is the metabolic pathway that converts glucose () into pyruvic acid, pyruvate and, in most organisms, occurs in the liquid part of cells (the cytosol). The Thermodynamic free energy, free energy released in this process is used to form the high-energy molecules adenosine triphosphate (ATP) and NADH, reduced nicotinamide adenine dinucleotide (NADH). Glycolysis is a sequence of ten reactions catalyzed by enzymes. The wide occurrence of glycolysis in other species indicates that it is an ancient metabolic pathway. Indeed, the reactions that make up glycolysis and its parallel pathway, the pentose phosphate pathway, can occur in the Great Oxygenation Event, oxygen-free conditions of the Archean oceans, also in the absence of enzymes, catalyzed by metal ions, meaning this is a plausible prebiotic pathway for abiogenesis. The most common type of glycolysis is the ''Embden–Meyerhof–Parnas (EMP) pathway'', which was discovered by Gustav Embden, Otto Meyerhof, and Jakub Kar ...
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Copenhagen
Copenhagen ( ) is the capital and most populous city of Denmark, with a population of 1.4 million in the Urban area of Copenhagen, urban area. The city is situated on the islands of Zealand and Amager, separated from Malmö, Sweden, by the Øresund strait. The Øresund Bridge connects the two cities by rail and road. Originally a Vikings, Viking fishing village established in the 10th century in the vicinity of what is now Gammel Strand, Copenhagen became the capital of Denmark in the early 15th century. During the 16th century, the city served as the ''de facto'' capital of the Kalmar Union and the seat of the Union's monarchy, which governed most of the modern-day Nordic countries, Nordic region as part of a Danish confederation with Sweden and Norway. The city flourished as the cultural and economic centre of Scandinavia during the Renaissance. By the 17th century, it had become a regional centre of power, serving as the heart of the Danish government and Military history ...
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Solomon Family
Samuel Moss Solomon (c. 1769 – 13 May 1842) was an early Jewish settler in Australia, amongst whose descendants many achieved a degree of notability. The relationship between these descendants is complicated by three factors: the duplication of names, not only within a family line but across lines; the number of intra-family marriages; and marriages to people with the same surname but not closely related. This list is not exhaustive but includes most family members likely to be found in Wikipedia and Australian newspapers. History Samuel Moss Solomon had a business in London manufacturing pencils, though reports of him being an inventor or even a major manufacturer are unsupportable. He married Elizabeth Moses (c. 1772–c. 1814) and had four sons: Moss Samuel, Emanuel, Vaiben and Phillip, and four daughters: Susan, Hannah, Sarah and Esther. After the death of Elizabeth he married Esther Davis (31 December 1774 – 13 July 1875), with whom he had another two children, Isaac and ...
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Valdemar Henriques
Waldemar, Valdemar, Valdimar, or Woldemar is an Old High German Old High German (OHG; ) is the earliest stage of the German language, conventionally identified as the period from around 500/750 to 1050. Rather than representing a single supra-regional form of German, Old High German encompasses the numerous ... given name. It consists of the elements ''wald-'' "power", "brightness" and ''-mar'' "fame". The name is considered the equivalent of the Latvian name Valdemārs, the Estonian name Voldemar, and the Slavic names Vladimir, Volodymyr, Uladzimir or Włodzimierz (given name), Włodzimierz. The Old Norse form ''Valdamarr'' (also ''Valdarr'') occurs in the Guðrúnarkviða II as the name of a king of the Danes. The Old Norse form is also used in Heimskringla, in the story of Harald Hardrada, as the name of a ruler of Holmgard (Veliky Novgorod).Alison Finlay (2004). ''Fagrskinna: A Catalogue of the Kings of Norway''. Brillp. 236 The ''Fagrskinna'' kings' sagas also have '' ...
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