Drosophila Genetic Reference Panel
''Drosophila'' Genetic Reference Panel (DGRP) is a suite of ''Drosophila melanogaster'' lines derived from an out-crossed population in Raleigh, North Carolina. The founders of these lineages were collected from the Raleigh State Farmer's Market . The suite consists of 205 fully sequenced lines which have been inbred to near homozygosity. The primary goal of the DGRP is to provide a common set of strain for quantitative genetics research in ''Drosophila''. Each researcher who uses the lines from the DGRP will have access to other researchers' data, which will be stored in a publicly available database. This allows for analyses to be performed across studies without having to worry about complications arising from different labs using genomically different lines of fruit flies. Objectives These lines are useful for performing QTL maps, as every line is fully sequenced. This allows for association mapping to be performed, which looks for genomic regions that are correlated to a ph ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the " vinegar fly" or " pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Baylor College Of Medicine
Baylor College of Medicine (BCM) is a medical school and research center in Houston, Texas, within the Texas Medical Center, the world's largest medical center. BCM is composed of four academic components: the School of Medicine, the Graduate School of Biomedical Sciences; the School of Health Professions, and the National School of Tropical Medicine. The school is part owner, alongside Catholic Health Initiatives (CHI), of Baylor St. Luke's Medical Center, the flagship hospital of the CHI St. Luke's Health system. Other affiliated teaching hospitals and research institutes include Harris Health System's Ben Taub Hospital, Texas Children's Hospital, The University of Texas MD Anderson Cancer Center, TIRR Memorial Hermann, the Menninger Clinic, the Michael E. DeBakey VA Medical Center, and the Children's Hospital of San Antonio. On November 18, 2020, Baylor College of Medicine announced a new affiliation with Baylor Scott & White Health. This will result in the development o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Shaker (gene)
The ''shaker (Sh)'' gene, when mutated, causes a variety of atypical behaviors in the fruit fly, ''Drosophila melanogaster''. Under ether anesthesia, the fly’s legs will shake (hence the name); even when the fly is unanaesthetized, it will exhibit aberrant movements. Sh-mutant flies have a shorter lifespan than regular flies; in their larvae, the repetitive firing of action potentials as well as prolonged exposure to neurotransmitters at neuromuscular junctions occurs. In ''Drosophila'', the shaker gene is located on the X chromosome. The closest human homolog is KCNA3. Function The ''Sh'' gene plays a part in the operation of potassium ion channels, which are integral membrane proteins and are essential to the correct functioning of the cell. A working shaker channel is voltage-dependent and has four subunits, which form a pore through which ions flow, carrying type-A potassium current (IA). A mutation in the Sh gene reduces the conductance of charge across the neuron ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rutabaga
Rutabaga (; North American English) or swede (British English and some Commonwealth English) is a root vegetable, a form of ''Brassica napus'' (which also includes rapeseed). Other names include Swedish turnip, neep (Scots), and Turnip (terminology), turnip (Scottish and Canadian English, Hiberno-English, Irish English and Manx English). However, elsewhere the name "turnip" usually refers to the related turnip, white turnip. The species ''Brassica napus'' Triangle of U, originated as a Hybrid (biology), hybrid between the cabbage (''Brassica oleracea'') and the turnip (''Brassica rapa''). Rutabaga roots are eaten as human food in various ways, and the leaves can be eaten as a leaf vegetable. The roots and tops are also used for livestock, either fed directly in the winter or foraged in the field during the other seasons. Scotland, Northern and Western England, Wales, the Isle of Man and Ireland had a tradition of carving the roots into lanterns at Halloween. Etymology Rutab ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sleep Behavior
Sleep is a sedentary state of mind and body. It is characterized by altered consciousness, relatively inhibited sensory activity, reduced muscle activity and reduced interactions with surroundings. It is distinguished from wakefulness by a decreased ability to react to stimuli, but more reactive than a coma or disorders of consciousness, with sleep displaying different, active brain patterns. Sleep occurs in repeating periods, in which the body alternates between two distinct modes: REM sleep and non-REM sleep. Although REM stands for "rapid eye movement", this mode of sleep has many other aspects, including virtual paralysis of the body. Dreams are a succession of images, ideas, emotions, and sensations that usually occur involuntarily in the mind during certain stages of sleep. During sleep, most of the body's systems are in an anabolic state, helping to restore the immune, nervous, skeletal, and muscular systems; these are vital processes that maintain mood, memory, and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Massachusetts
Massachusetts (Massachusett language, Massachusett: ''Muhsachuweesut [Massachusett writing systems, məhswatʃəwiːsət],'' English: , ), officially the Commonwealth of Massachusetts, is the most populous U.S. state, state in the New England region of the Northeastern United States. It borders on the Atlantic Ocean and Gulf of Maine to the east, Connecticut and Rhode Island to the south, New Hampshire and Vermont to the north, and New York (state), New York to the west. The state's capital and List of municipalities in Massachusetts, most populous city, as well as its cultural and financial center, is Boston. Massachusetts is also home to the urban area, urban core of Greater Boston, the largest metropolitan area in New England and a region profoundly influential upon American History of the United States, history, academia, and the Economy of the United States, research economy. Originally dependent on agriculture, fishing, and trade. Massachusetts was transformed into a manuf ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Boston
Boston (), officially the City of Boston, is the capital city, state capital and List of municipalities in Massachusetts, most populous city of the Commonwealth (U.S. state), Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th-List of United States cities by population, most populous city in the country. The city boundaries encompass an area of about and a population of 675,647 2020 U.S. Census, as of 2020. It is the seat of Suffolk County, Massachusetts, Suffolk County (although the county government was disbanded on July 1, 1999). The city is the economic and cultural anchor of a substantially larger metropolitan area known as Greater Boston, a metropolitan statistical area (MSA) home to a census-estimated 4.8 million people in 2016 and ranking as the tenth-largest MSA in the country. A broader combined statistical area (CSA), generally corresponding to the commuting area and includ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genetics Society Of America
The Genetics Society of America (GSA) is a scholarly membership society of more than 5,500 genetics researchers and educators, established in 1931. The Society was formed from the reorganization of the Joint Genetics Sections of the American Society of Zoologists and the Botanical Society of America. An Abridged History of the Genetics Society of America GSA members conduct fundamental and applied research using a wide variety of model organisms to enhance understanding of living systems. Some of the systems of study include '''' (fruit flies), '' [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Texas Medical Center
The Texas Medical Center (TMC) is a medical district and neighborhood in south-central Houston, Texas, United States, immediately south of the Museum District and west of Texas State Highway 288. Over 60 medical institutions, largely concentrated in a triangular area between Brays Bayou, Rice University, and Hermann Park, are members of the Texas Medical Center Corporation—a non-profit umbrella organization—which constitutes the largest medical complex in the world. The TMC has an extremely high density of clinical facilities for patient care, basic science, and translational research. The Texas Medical Center employs over 106,000 people, hosts 10 million patient encounters annually, and has a gross domestic product of US$25 billion. Over the decades, the TMC has expanded south of Brays Bayou towards NRG Park, and the organization has developed ambitious plans for a new "innovation campus" south of the river. The Medical Center / Astrodome area, highly populated with med ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Stephen Richards (biologist)
Stephen, Steven, Steve or Stevie Richards may refer to: Arts and entertainment * Mark Stevens (actor) (a.k.a. Stephen Richards, 1916–1994), American actor * Steve Richards (born 1960), British television and radio presenter and newspaper political columnist * Stephen Richards (musician) (born 1977), American vocalist and guitarist in the rock music group Taproot Sports * Steve Richards (footballer) (born 1961), Scottish footballer * Stephen Richards (canoeist) (born 1965), New Zealand sprint canoer * Stevie Richards (Michael Manna, born 1971), American wrestler * Steven Richards (born 1972), Australian racing driver Others * Stephen Richards (politician) (1820–1894), Canadian lawyer and politician * Stephen Richards (murderer) (1854–1879), American serial killer * Stephen L Richards (1879–1959), American religious leader * Sir Stephen Richards (judge) (born 1950), Welsh jurist, Lord Justice of Appeal * Stephen Richards (business executive) Stephen D. Richards is a New ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Richard Gibbs (biologist)
Richard Alexander Gibbs, , is an Australian geneticist. He is currently the Wofford Cain Chair and Professor of Molecular and Human Genetics at Baylor College of Medicine in Houston, Texas. In 1996, he founded the Human Genome Sequencing Center at BCM, which was one of five worldwide sites selected to complete the final phase of the Human Genome Project The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a .... References External linksRichard A. Gibbs, Ph.D.(Department of Molecular and Human Genetics, Baylor College of Medicine) 1950s births Living people Australian geneticists Companions of the Order of Australia University of Melbourne alumni Australian expatriates in the United States Human Genome Project scientists Members of the National Academy of Medicine {{Au ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |