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Donald Jeffries
Professor Donald Jeffries (29 August 1941 – 7 December 2011) was a British virologist and academic. He was a leading expert on the Human Immunodeficiency Virus (HIV) that causes AIDS. Education Jeffries was educated at the William Ellis Grammar School in Highgate, North London, and then did medical training at the Royal Free Hospital School, from where he qualified in 1966. Career Jeffries began his career at St Mary's Hospital Medical School in Paddington as senior registrar in microbiology. He remained at St Mary’s until 1990, by when he had become a reader in virology and the director of clinical studies. Whilst at St Mary’s Jeffries led a team which developed the antiretroviral drug Saquinavir, the first protease inhibitor used for HIV treatment, in collaboration with the pharmaceutical company Roche. In 1990 Jeffries moved to St Bartholomew’s Hospital Medical College, where he was appointed University of London Professor of Virology. At St Bartholomew’s Jeffries ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virology
Virology is the Scientific method, scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host (biology), host cell (biology), cells for reproduction, their interaction with host organism physiology and immunity, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy. The identification of the causative agent of tobacco mosaic disease (TMV) as a novel pathogen by Martinus Beijerinck (1898) is now acknowledged as being the history of virology, official beginning of the field of virology as a discipline distinct from bacteriology. He realized the source was neither a bacterial nor a fungal infection, but something completely different. Beijerinck used the word "virus" to describe the mysterious agent in his 'contagium vivum fluidum' ('contagious living fluid'). Rosalind Franklin proposed the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barts And The London School Of Medicine And Dentistry
Barts and The London School of Medicine and Dentistry, commonly known as Barts or BL, is a medical school, medical and dental school in London, England. The school is part of Queen Mary University of London, a constituent college of the federal University of London, and the United Hospitals. It was formed in 1995 by the merger of the London Hospital Medical College (the first school to be granted an official charter for medical teaching in 1785) and the Medical College of St Bartholomew's Hospital (established in 1843, with medical teaching dating back to the founding of the hospital in 1123). It is widely considered to be one of the top medical schools in the world. The school has multiple sites, having a presence at the site of both of the former colleges at and near their respective hospitals, St Bartholomew's Hospital (in Smithfield, London, Smithfield in the City of London and nearby in Charterhouse Square), and the Royal London Hospital in Whitechapel with an additional si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Virologists
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories and Crown Dependencies. * British national identity, the characteristics of British people and culture * British English, the English language as spoken and written in United Kingdom of Great Britain and Northern Ireland and, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *People or things associated with: ** Great Britain, an island ** British Isles, an island group ** United Kingdom, a sovereign state ** British Empire, a historical global colonial empire ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) * British Raj, colonial India under the British Empire * British Hong Kong, colonial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2011 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1941 Births
The Correlates of War project estimates this to be the deadliest year in human history in terms of conflict deaths, placing the death toll at 3.49 million. However, the Uppsala Conflict Data Program estimates that the subsequent year, 1942, was the deadliest such year. Death toll estimates for both 1941 and 1942 range from 2.28 to 7.71 million each. Events Below, the events of World War II have the "WWII" prefix. January * January–August – 10,072 men, women and children with mental and physical disabilities are asphyxiated with carbon monoxide in a gas chamber, at Hadamar Euthanasia Centre in Germany, in the first phase of mass killings under the Aktion T4 program here. * January 1 – Thailand's Prime Minister Plaek Phibunsongkhram decrees January 1 as the official start of the Thai solar calendar new year (thus the previous year that began April 1 had only 9 months). * January 3 – A decree (''Normalschrifterlass'') promulgated in Germany by Martin Bormann ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of The British Empire
The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two of which make the recipient either a Orders, decorations, and medals of the United Kingdom#Modern honours, knight if male or a dame (title), dame if female. There is also the related British Empire Medal, whose recipients are affiliated with the order, but are not members of it. The order was established on 4 June 1917 by King George V, who created the order to recognise 'such persons, male or female, as may have rendered or shall hereafter render important services to Our Empire'. Equal recognition was to be given for services rendered in the UK and overseas. Today, the majority of recipients are UK citizens, though a number of Commonwealth realms outside the UK continue to make appointments to the order. Honorary awards may be made to cit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Association Of British Insurers
The Association of British Insurers, or ABI, is a trade association made up of insurance companies in the United Kingdom. History The ABI began in 1985 after several specialised insurance industry trade associations joined to form one trade association for the UK insurance industry (excluding Lloyd's of London), including the British Insurance Association, the Life Offices’ Association, the Fire Offices Committee, the Accident Offices Association, the Industrial Life Offices Association and the Accident Offices Association (Overseas). The UK insurance industry is the largest in Europe and the third largest in the world. In 2014, there was a "shock" announcement that Legal & General was leaving as one of ABI's around 300 corporate members, due to the ABI's "decision to transfer its investment business to the Investment Management Association." ABI, says the ''Insurance Journal'', warned about modern building materials like external cladding posing a fire risk before the Grenf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal College Of Pathologists
The Royal College of Pathologists (RCPath) is a professional membership organisation. Its main function is the overseeing of postgraduate training, and its Fellowship Examination (FRCPath) is recognised as the standard assessment of fitness to practise in this branch of medicine. Constitution The Royal College of Pathologists is a professional membership organisation, to maintain the standards and reputation of British pathology, through training, assessments, examinations and professional development. It is a registered charity and is not a trade union. Its 13,000 members work in hospital laboratories, universities and industry worldwide. History The College of Pathologists was founded in 1962, to optimise postgraduate training in the relatively young science of pathology, with its high importance in the diagnostic process, and the increasing range of specialist studies within it. The college received its royal charter in 1970 and its Patron is King Charles III. Training and e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hoffmann-La Roche
F. Hoffmann-La Roche AG, commonly known as Roche (), is a Swiss multinational holding healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth-largest pharmaceutical company in the world by revenue and the leading provider of cancer treatments globally. In 2023, the company’s seat in Forbes Global 2000 was 76. The company owns the American biotechnology company Genentech, which is a wholly owned independent subsidiary, and the Japanese biotechnology company Chugai Pharmaceuticals, as well as the United States–based companies Ventana and Foundation Medicine. Roche's revenues during fiscal year 2020, were 58.32 billion Swiss francs. Descendants of the founding Hoffmann and Oeri families own slightly over half of the bearer shares with voting rights (a pool of family shareholders 45%, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HIV/AIDS
The HIV, human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a Preventive healthcare, preventable disease. It can be managed with treatment and become a manageable chronic health condition. While there is no cure or vaccine for HIV, Management of HIV/AIDS, antiretroviral treatment can slow the course of the disease, and if used before significant disease progression, can extend the life expectancy of someone living with HIV to a nearly standard level. An HIV-positive person on treatment can expect to live a normal life, and die with the virus, not of it. Effective #Treatment, treatment for HIV-positive people (people living with HIV) involves a life-long regimen of medicine to suppress the virus, making the viral load undetectable. Treatment is recommended as soon as the diagnosis is made. An HIV-positive person who has an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saquinavir
Saquinavir, sold under the brand name Invirase among others, is an antiretroviral medication used together with other medications to treat or prevent HIV/AIDS. Typically it is used with ritonavir or lopinavir/ritonavir to increase its effect. It is taken by mouth. Common side effects include nausea, vomiting, diarrhea, and feeling tired. More serious side effects include problems with QT prolongation, heart block, high blood lipids, and liver problems. It appears to be safe in pregnancy. It is in the protease inhibitor class and works by blocking the HIV protease. Saquinavir was patented in 1988 and first sold in 1995. Medical uses Saquinavir is used together with other medications to treat or prevent HIV/AIDS. Typically it is used with ritonavir or lopinavir/ritonavir to increase its effect. Side effects The most frequent adverse events with saquinavir in either formulation are mild gastrointestinal symptoms, including diarrhoea, nausea, loose stools and abdominal dis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
St Mary's Hospital Medical School
St Mary's Hospital Medical School was the youngest of the constituent medical schools of Imperial College School of Medicine, founded in 1854 as part of the new hospital in Paddington. During its existence in the 1980s and 1990s, it was the most popular medical school in the country, with an application to place ratio of 27:1 in 1996. St Mary's continued comparatively unmoved by the other nomadic medical schools in the area, until its merger with Imperial College in 1988, and the foundation of Imperial College School of Medicine in 1997 by the merger with Charing Cross and Westminster Medical School. ''Doctors to Be'' '' Doctors to Be'', a biographical documentary series first broadcast on BBC Two by BBC Television, followed 10 medical students who enrolled at St Mary's Hospital Medical School in the 1985 intake. It started with admission interviews in November 1984, then followed their lives as medical students for five or six years, and ended with their first experiences of w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
