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Dipropyllysergamide
Lysergic acid dipropylamide (LSDP), also known as ''N'',''N''-dipropyllysergamide (DPL), is a psychedelic drug of the substituted lysergamide, lysergamide family related to lysergic acid diethylamide (LSD). It is the structural analog, analogue of LSD in which the amide functional group, group has two propyl chemical substituent, substitutions instead of two ethyl group, ethyl substituents. The drug has about 10% or less of the potency (pharmacology), potency of LSD as a psychedelic and its dose is greater than 1mg oral administration, orally. It has been reported however that, in contrast to LSD, LSDP produces LSD-like Autonomic nervous system, autonomic effects at much lower doses (<1mg) than those at which its psychedelic effects occur. The drug was initially thought to be non-hallucinogenic after only being tested at sub-milligram doses. LSDP was f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituted Lysergamide
Lysergamides, also known as ergoamides or as lysergic acid amides, are amides of lysergic acid (LA). They are ergolines, with some lysergamides being found naturally in ergot as well as other fungi. Lysergamides are notable in containing embedded phenethylamine and tryptamine moieties within their ergoline ring system. The simplest lysergamides are ergine (lysergic acid amide; LSA) and isoergine (iso-lysergic acid amide; iso-LSA). In terms of pharmacology, the lysergamides include numerous serotonin and dopamine receptor agonists, most notably the psychedelic drug lysergic acid diethylamide (LSD) but also a number of pharmaceutical drugs like ergometrine, methylergometrine, methysergide, and cabergoline. Various analogues of LSD, such as the psychedelics ALD-52 (1A-LSD), ETH-LAD, LSZ, and 1P-LSD and the non-hallucinogenic 2-bromo-LSD (BOL-148), have also been developed. Ergopeptines like ergotamine, dihydroergotamine, and bromocriptine are also lysergamides, but with a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oral Administration
Oral administration is a route of administration whereby a substance is taken through the Human mouth, mouth, swallowed, and then processed via the digestive system. This is a common route of administration for many medications. Oral administration can be easier and less painful than other routes of administration, such as Injection (medicine), injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients able to swallow. Terminology ''Per os'' (; ''P.O.'') is an adverbial phrase meaning literally from Latin "through the mouth" or "by mouth". The expression is used in medicine to describe a treatment that is taken orally (but not ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heffter Research Institute
The Heffter Research Institute is a 501(c)(3) nonprofit organization that promotes research with classic hallucinogens and Psychedelic drug, psychedelics, predominantly psilocybin, to contribute to a greater understanding of the mind and to alleviate suffering. Founded in 1993 as a virtual institute, Heffter primarily funds academic and clinical scientists and made more than $3.1 million in grants between 2011 and 2014. Heffter's recent clinical studies have focused on psilocybin-assisted treatment for end-of-life anxiety and Major depressive disorder, depression in cancer patients, as well as alcohol and nicotine addiction. History Arthur Heffter Arthur Heffter was a German chemist/pharmacologist/physician who first isolated pure Mescaline from the peyote cactus in the late 1890s. He also proved that mescaline was the alkaloid in the cactus that is responsible for its psychoactive properties. This was the first psychedelic compound to be isolated and identified from its natur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethylpropyllysergamide
''N''-Ethyl-''N''-propyllysergamide (EPLA), also known as lysergic acid ethylpropylamide (LEP or LEP-57), is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is the analogue of LSD in which the amide group has one ethyl group and one propyl group instead of two ethyl groups. The drug shows affinity for serotonin receptors and acts as a serotonin 5-HT2A receptor agonist similarly to LSD. EPLA has about one-third of the potency of LSD in producing psychedelic effects in humans. Its exact dosage has not been reported. EPLA was first described in the scientific literature by at least 1959. It was reportedly encountered as a designer drug A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ... by the 1990s. See also * Lysergic acid methylpr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lysergic Acid Diallylamide
''N'',''N''-Diallyllysergamide (DAL, as the tartrate salt), also known as lysergic acid diallylamide, is a psychedelic lysergamide related to lysergic acid diethylamide (LSD). In their book ''TiHKAL'', Alexander and Ann Shulgin describe it as being "an order of magnitude less potent than LSD itself". See also * Substituted lysergamide Lysergamides, also known as ergoamides or as lysergic acid amides, are amides of lysergic acid (LA). They are ergolines, with some lysergamides being found naturally in ergot as well as other fungi. Lysergamides are notable in containing embed ... * Lysergic acid dimethylamide (DAM-57) * Lysergic acid dipropylamide (DPL) * Lysergic acid dibutylamide (LBB-66) References Allylamines Psychedelic lysergamides Serotonin receptor agonists {{Hallucinogen-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lysergic Acid Dibutylamide
LBB-66, also known as lysergic acid dibutylamide or as ''N'',''N''-dibutyllysergamide, is a serotonin receptor modulator of the lysergamide family related to lysergic acid diethylamide (LSD; LSD-25). It is the derivative of LSD in which the ''N'',''N''-diethyl groups have been replaced with ''N'',''N''-dibutyl groups. The drug has about 31% or around one-third of the antiserotonergic activity of LSD in the isolated rat uterus ''in vitro''. In contrast to other assessed lysergamides, it has been said to bind practically irreversibly in this context. Unlike LSD, LBB-66 is said to be devoid of psychedelic effects in humans, with a hallucinogenic potency relative to LSD of 0% stated, but the tested doses not given. LBB-66 was first described in the scientific literature by Albert Hofmann and colleagues by 1955. See also * Substituted lysergamide * Lysergic acid dimethylamide (DAM-57) * Lysergic acid dipropylamide (DPL) * Lysergic acid diallylamide ''N'',''N''-Diallyllysergamide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lysergic Acid Dimethylamide
DAM-57, also known as ''N'',''N''-dimethyllysergamide (DAM) or as lysergic acid dimethylamide, is a derivative of ergine. There has been a single report of observing N,N-dimethyl-D-lysergamide in the illicit drug market. This compound did induce autonomic disturbances at oral levels of some ten times the dosage required for lysergic acid diethylamide (LSD), presumably in the high hundreds of micrograms. There is some disagreement as to whether there were psychic changes observed.; It was first described in the scientific literature by Albert Hofmann and colleagues by 1955. See also * Substituted lysergamide * Lysergic acid methylamide (LAM) * Lysergic acid dipropylamide (DPL) * Lysergic acid diallylamide ''N'',''N''-Diallyllysergamide (DAL, as the tartrate salt), also known as lysergic acid diallylamide, is a psychedelic lysergamide related to lysergic acid diethylamide (LSD). In their book ''TiHKAL'', Alexander and Ann Shulgin describe it as bei ... (DAL) References ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lysergic Acid Methylpropylamide , a luxury fabric
{{Disambig, geo, surname ...
Lampa may refer to: Places * Lampa, Chile, a Chilean town in the Province of Chacabuco, Metropolitan Region of Santiago * Lampa, China, an alternative name for Lampacau, an island in the Pearl River Delta * Lampa (Crete), a town of ancient Crete, Greece * Lampa, Peru ** Lampa Province, Peru * Lampa, Poland Other * Rachael Lampa, Christian pop and rock singer * ''Lampa'' (film) (''Lamp''), a Polish film * LAMPA, an abbreviation for lysergic acid methylpropylamide * Lampa (see), a former bishopric and current titular see of the Roman Catholic Church See also *Lampas Lampas is a type of luxury Textile, fabric created on a draw loom with a background weft (a "ground weave") typically in taffeta with supplementary wefts (the "pattern wefts") laid on top and forming a design, sometimes also with a "Brocade, broca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Hofmann
Albert Hofmann (11 January 1906 – 29 April 2008) was a Swiss chemist known for being the first to synthesize, ingest, and learn of the psychedelic effects of lysergic acid diethylamide (LSD). Hofmann's team also isolated, named and synthesized the principal psychedelic mushroom compounds psilocybin and psilocin. He authored more than 100 scientific articles and numerous books, including ''LSD: Mein Sorgenkind'' (''LSD: My Problem Child''). In 2007, he shared first place with Tim Berners-Lee on a list of the 100 greatest living geniuses published by ''The Daily Telegraph'' newspaper. Early life and education Albert Hofmann was born in Baden, Switzerland, on 11 January 1906. He was the first of four children to factory toolmaker Adolf Hofmann and Elisabeth ( Schenk) and was baptized Protestant. When his father became ill, Hofmann obtained a position as a commercial apprentice in concurrence with his studies. Owing to his father's low income, Albert's godfather paid for his e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autonomic Nervous System
The autonomic nervous system (ANS), sometimes called the visceral nervous system and formerly the vegetative nervous system, is a division of the nervous system that operates viscera, internal organs, smooth muscle and glands. The autonomic nervous system is a control system that acts largely unconsciously and regulates bodily functions, such as the heart rate, its Myocardial contractility, force of contraction, digestion, respiratory rate, pupillary dilation, pupillary response, Micturition, urination, and Animal sexual behaviour, sexual arousal. The fight-or-flight response, also known as the acute stress response, is set into action by the autonomic nervous system. The autonomic nervous system is regulated by integrated reflexes through the brainstem to the spinal cord and organ (anatomy), organs. Autonomic functions include control of respiration, heart rate, cardiac regulation (the cardiac control center), vasomotor activity (the vasomotor center), and certain reflex, reflex ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
