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Diacylhydrazine Insecticide
The diacylhydrazines, also known as bisacylhydrazines (BAHs) or dibenzoylhydrazines are appropriately substituted derivatives of dibenzoyl hydrazine. They do not immediately kill the insect, but produces premature unsuccessful moulting, which then causes the death of the insect. BAHs thus belong to the class of insect growth regulators. The insecticidal activity of RH-5849 was discovered serendipitously in 1984 at Rohm and Haas, who later commercialised tebufenozide methoxyfenozide, and halofenozide. Later other companies commercialised chromafenozide and fufenozide. The EPA removed halofenozide from the market in 2012 on the request of the manufacturer. BAHs were estimated to account for ca 1% of the 18.4-billion-dollar 2018 global pesticide market. BAHs are used against lepidoptera, with some applications against coleopteran and dipteran pests. Many plants produce chemicals ( phytoecdysteroids) which use this mode of action to kill insects. BAHs act by agonising the ecdyson ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Agriculture Organization Of The United Nations
The Food and Agriculture Organization of the United Nations; . (FAO) is a specialized agency of the United Nations that leads international efforts to defeat hunger and improve nutrition and food security. Its Latin motto, , translates to "let there be bread". It was founded on 16 October 1945. The FAO comprises 195 members, including 194 countries and the European Union. Its headquarters is in Rome, Italy, and it maintains regional and field offices worldwide, operating in over 130 countries. It helps governments and development agencies coordinate their activities to improve and develop agriculture, forestry, fisheries, and land and water resources. It also conducts research, provides technical assistance to projects, operates educational and training programs, and collects agricultural output, production, and development data. The FAO is governed by a biennial conference representing each member country and the European Union, which elects a 49-member executive counci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insect Growth Regulator
An insect growth regulator (IGR) is a chemical insecticide that kills insects indirectly by disrupting their life cycles. The term was initially proposed to describe the effects of juvenile hormone analogs. Although the term "insect growth disruptor" more accurately describes the actions of IGRs, it did not become widely used. IGRs encompass chemical classes with three modes of action ( mechanisms of action): juvenile hormone analogs, chitin synthesis inhibitors, and ecdysone receptor agonists. Juvenile Hormone analogs Juvenile hormone analogs are also known as juvenile hormone mimics, juvenoids, or JH signaling activators. Juvenile hormone (JH) controls many important processes in insects including metamorphosis. After the structure determination of the JHs in the 1960s, the search for more stable and useable analogs started. Zoecon introduced methoprene in 1975, and later hydroprene and kinoprene. Later again other companies introduced the more stable fenoxycarb and pyripro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tebufenozide
Tebufenozide is an insecticide that acts as a molting hormone. It is an agonist of the ecdysone receptor that causes premature molting in larvae. It is primarily used against caterpillar pests. It belongs to the class of diacylhydrazines. Because it has high selectivity for the targeted pests and low toxicity otherwise, the company that discovered tebufenozide, Rohm and Haas, was given a Presidential Green Chemistry Award for its development. Its environmental half-life varies according to where it is released and under what conditions, but can be said to be on the order of months. It is used as an insect growth regulator, to control leaf-eating insects that cause damage or death in trees. Tebufenozide is the active ingredient in" Bayer's MIMIC formulation, which controls forest defoliator pests such as gypsy moths, tent caterpillars, budworms, tussock moths and cabbage looper. These are all pests of the order Lepidoptera. It has been used against the sugarcane borer, alth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lepidoptera
Lepidoptera ( ) or lepidopterans is an order (biology), order of winged insects which includes butterflies and moths. About 180,000 species of the Lepidoptera have been described, representing 10% of the total described species of living organisms, making it the second largest insect order (behind Coleoptera) with 126 family (biology), families and 46 Taxonomic rank, superfamilies, and one of the most widespread and widely recognizable insect orders in the world. Lepidopteran species are characterized by more than three derived features. The most apparent is the presence of scale (anatomy), scales that cover the torso, bodies, large triangular Insect wing, wings, and a proboscis for siphoning nectars. The scales are modified, flattened "hairs", and give butterflies and moths their wide variety of colors and patterns. Almost all species have some form of membranous wings, except for a few that have reduced wings or are wingless. Mating and the laying of eggs is normally performe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beetle
Beetles are insects that form the Taxonomic rank, order Coleoptera (), in the superorder Holometabola. Their front pair of wings are hardened into wing-cases, elytra, distinguishing them from most other insects. The Coleoptera, with about 400,000 described species, is the largest of all orders, constituting almost 40% of described arthropods and 25% of all known animal species; new species are discovered frequently, with estimates suggesting that there are between 0.9 and 2.1 million total species. However, the number of beetle species is challenged by the number of species in Fly, dipterans (flies) and hymenopterans (wasps). Found in almost every habitat except the sea and the polar regions, they interact with their ecosystems in several ways: beetles often feed on plants and fungi, break down animal and plant debris, and eat other invertebrates. Some species are serious agricultural pests, such as the Colorado potato beetle, while others such as Coccinellidae (ladybirds or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytoecdysteroid
Phytoecdysteroids are plant-derived ecdysteroids. Phytoecdysteroids are a class of chemicals that plants synthesize for defense against phytophagous (plant eating) insects. These compounds are mimics of hormones used by arthropods in the molting process known as ecdysis. It is presumed that these chemicals act as endocrine disruptors for insects, so that when insects eat the plants with these chemicals they may prematurely molt, lose weight, or suffer other metabolic damage and die. Chemically, phytoecdysteroids are classed as triterpenoids, the group of compounds that includes triterpene saponins, phytosterols, and phytoecdysteroids. Plants, but not animals, synthesize phytoecdysteroids from mevalonic acid in the mevalonate pathway of the plant cell using acetyl-CoA as a precursor. Some ecdysteroids, including ecdysone and 20-hydroxyecdysone (20E), are produced by both plants and arthopods. Besides those, over 250 ecdysteroid analog (chemistry), analogs have been identified ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mode Of Action
In pharmacology and biochemistry, mode of action (MoA) describes a functional or anatomical change, resulting from the exposure of a living organism to a substance. In comparison, a mechanism of action (MOA) describes such changes at the molecular level. A mode of action is important in classifying chemicals, as it represents an intermediate level of complexity in between molecular mechanisms and physiological outcomes, especially when the exact molecular target has not yet been elucidated or is subject to debate. A mechanism of action of a chemical could be "binding to DNA" while its broader mode of action would be "transcriptional regulation". However, there is no clear consensus and the term mode of action is also often used, especially in the study of pesticides, to describe molecular mechanisms such as action on specific nuclear receptors or enzymes. Despite this, there are classification attempts, such as the HRAC's classification Classification is the activity of assign ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plant Defense Against Herbivory
Plant defense against herbivory or host-plant resistance is a range of adaptations Evolution, evolved by plants which improve their fitness (biology), survival and reproduction by reducing the impact of herbivores. Many plants produce secondary metabolites, known as Heterotelergones, allelochemicals, that influence the behavior, growth, or survival of herbivores. These chemical defenses can act as repellents or toxins to herbivores or reduce plant digestibility. Another defensive strategy of plants is changing their attractiveness. Plant perception (physiology), Plants can sense being touched, and they can respond with strategies to defend against herbivores. Plants alter their appearance by changing their size or quality in a way that prevents overconsumption by large herbivores, reducing the rate at which they are consumed. Other defensive strategies used by plants include escaping or avoiding herbivores at any time in any placefor example, by growing in a location where plants ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agonist
An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an Receptor antagonist, antagonist blocks the action of the agonist, while an inverse agonist causes an action opposite to that of the agonist. Etymology The word originates from the Ancient Greek, Greek word (''agōnistēs''), "contestant; champion; rival" < (''agōn''), "contest, combat; exertion, struggle" < (''agō''), "I lead, lead towards, conduct; drive." Types of agonists Receptor (biochemistry), Receptors can be activated by either endogenous agonists (such as hormones and neurotransmitters) or exogenous agonists (such as medication, drugs), resulting in a biological response. A physiological agonism an ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ecdysone Receptor
The ecdysone receptor is a nuclear receptor found in arthropods, where it controls development and contributes to other processes such as reproduction. The receptor is a non-covalent heterodimer of two proteins, the EcR protein and ultraspiracle protein (USP). It binds to and is activated by ecdysteroids. Insect ecdysone receptors are currently better characterized than those from other arthropods, and mimics of ecdysteroids are used commercially as caterpillar-selective insecticides. Function Pulses of 20-hydroxyecdysone occur during insect development, whereupon this hormone binds to the ecdysone receptor, a ligand-activated transcription factor found in the nuclei of insect cells. This in turn leads to the activation of many other genes, as evidenced by puffing of polytene chromosomes at over a hundred sites. Ultimately the activation cascade causes physiological changes that result in ecdysis (moulting). The temporal expression of ecdysone receptor within neural st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pesticide Poisoning
A pesticide poisoning occurs when pesticides, chemicals intended to control a pest, affect non-target organisms such as humans, wildlife, plants, or bees. There are three types of pesticide poisoning. The first of the three is a single and short-term very high level of exposure which can be experienced by individuals who die by suicide, as well as pesticide formulators. The second type of poisoning is long-term high-level exposure, which can occur in pesticide formulators and manufacturers. The third type of poisoning is a long-term low-level exposure, which individuals are exposed to from sources such as pesticide residues in food as well as contact with pesticide residues in the air, water, soil, sediment, food materials, plants and animals. In developing countries, such as Sri Lanka, pesticide poisonings from short-term very high level of exposure (acute poisoning) is the most worrisome type of poisoning. However, in developed countries, such as Canada, it is the complete o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Environmental Impact Of Pesticides
The environmental effects of pesticides describe the broad series of consequences of using pesticides. The unintended consequences of pesticides is one of the main drivers of the negative impact of modern industrial agriculture on the environment. Pesticides, because they are toxic chemicals meant to kill pest species, can affect non-target species, such as plants, animals and humans. Over 98% of sprayed insecticides and 95% of herbicides reach a destination other than their target species, because they are sprayed or spread across entire agricultural fields. Other agrochemicals, such as fertilizers, can also have negative effects on the environment. The negative effects of pesticides are not just in the area of application. Runoff and pesticide drift can carry pesticides into distant aquatic environments or other fields, grazing areas, human settlements and undeveloped areas. Other problems emerge from poor production, transport, storage and disposal practices.Tashkent (1998 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
