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David Charles (physician)
David Charles is an American neurologist, professor and vice-chair of neurology, and the medical director of Telehealth at Vanderbilt University Medical Center. Education David Charles attended Vanderbilt University School of Medicine, graduating in 1990. After completing his neurology residency at Vanderbilt University Medical Center, he joined the faculty of the Department of Neurology at Vanderbilt University in 1994. In 1995, he obtained his fellowship in Movement Disorders and Clinical Neurophysiology. In 1996, he completed the Health Care Management Program from the Owen Graduate School of Management. In January and May 1997, he completed Harvard Macy Institute's Program for Physician Educators, and in 1998, he studied deep brain stimulation, and its use as a treatment of Parkinson's disease as a Fulbright Senior Scholar at the Universitaire de Grenoble in Grenoble, France. Professional activities Charles is president of the Clinical Neurological Society of America, co-cha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Decatur, Alabama
Decatur () is the largest city and county seat of Morgan County, Alabama, Morgan County (with a portion also in Limestone County, Alabama, Limestone County) in the U.S. state of Alabama. Nicknamed "The River City," it is located in North Alabama, northern Alabama on the banks of Wheeler Lake along the Tennessee River. The population was 57,938 at the 2020 United States census, 2020 census. Decatur is the core city of the two-county large Decatur metropolitan area, Alabama, Decatur metropolitan area, with an estimated population of 157,425 in 2022. Combined with the Huntsville Metropolitan Area, the two create the Huntsville-Decatur Combined Statistical Area, of which Decatur is the second-largest city. Like many southern cities in the early 19th century, Decatur's early success was based upon its location along a river. Railroad routes and boating traffic pushed the city to the front of North Alabama's economic atmosphere. The city rapidly grew into a large economic center with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Movement Disorders
Movement disorders are clinical syndromes with either an excess of movement or a paucity of voluntary and involuntary movements, unrelated to weakness or spasticity. Movement disorders present with extrapyramidal symptoms and are caused by basal ganglia disease. Movement disorders are conventionally divided into two major categories- '' hyperkinetic'' and '' hypokinetic''. Hyperkinetic movement disorders refer to dyskinesia, or excessive, often repetitive, involuntary movements that intrude upon the normal flow of motor activity. Hypokinetic movement disorders fall into one of four subcategories: akinesia (lack of movement), hypokinesia (reduced amplitude of movements), bradykinesia (slow movement), and rigidity. In primary movement disorders, the abnormal movement is the primary manifestation of the disorder. In secondary movement disorders, the abnormal movement is a manifestation of another systemic or neurological disorder. Treatment depends upon the underlying disorder. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vanderbilt University Faculty
Vanderbilt may refer to: People *Vanderbilt (surname) *Vanderbilt family Places In the United States: * Vanderbilt, California, a former gold-mining town * Vanderbilt, Michigan, a village * Vanderbilt, Nevada, a ghost town * Vanderbilt Mansion National Historic Site, Hyde Park, NY * Vanderbilt, Texas, a census-designated place * Vanderbilt, Pennsylvania, a borough * Vanderbilt Avenue, three New York City streets *Vanderbilt University, a private research university in Nashville, Tennessee, USA ** Vanderbilt Commodores, the athletics program of Vanderbilt University * Vanderbilt Museum, in Centerport, New York, built with a bequest from William Kissam Vanderbilt II Other uses *One Vanderbilt, a skyscraper in New York City *Vanderbilt Club, a bidding system in the game of contract bridge, devised by Harold S. Vanderbilt *Vanderbilt Cup, in American auto racing *George Vanderbilt Sumatran Expedition *Vanderbilt Mortgage and Finance, specializes in mortgages for manufactured homes * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School Alumni
Harvard University is a private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of colonial-era Massachusetts Bay Colony. While never formally affiliated with any denomination, Harvard trained Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston elite. Following the American Civil War, under Harvard president Charles William Eliot's long tenure from 1869 to 1909, Harvard developed multiple professional schools, which transforme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vanderbilt University School Of Medicine Alumni
Vanderbilt may refer to: People *Vanderbilt (surname) *Vanderbilt family Places In the United States: * Vanderbilt, California, a former gold-mining town *Vanderbilt, Michigan, a village * Vanderbilt, Nevada, a ghost town * Vanderbilt Mansion National Historic Site, Hyde Park, NY * Vanderbilt, Texas, a census-designated place * Vanderbilt, Pennsylvania, a borough *Vanderbilt Avenue, three New York City streets *Vanderbilt University, a private research university in Nashville, Tennessee, USA ** Vanderbilt Commodores, the athletics program of Vanderbilt University * Vanderbilt Museum, in Centerport, New York, built with a bequest from William Kissam Vanderbilt II Other uses *One Vanderbilt, a skyscraper in New York City *Vanderbilt Club, a bidding system in the game of contract bridge, devised by Harold S. Vanderbilt *Vanderbilt Cup, in American auto racing *George Vanderbilt Sumatran Expedition *Vanderbilt Mortgage and Finance, specializes in mortgages for manufactured homes *Va ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physicians From Alabama
A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases, and their treatment, which is the science of medicine, and a decent competence in its applied practice, which is the art or craft of the profession. Both the role of the physician and the meaning of the word itself vary ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Decatur, Alabama
The term "the people" refers to the public or common mass of people of a polity. As such it is a concept of human rights law, international law as well as constitutional law, particularly used for claims of popular sovereignty. In contrast, a people is any plurality of persons considered as a whole. Used in politics and law, the term "a people" refers to the collective or community of an ethnic group or nation. Concepts Legal Chapter One, Article One of the Charter of the United Nations states that "peoples" have the right to self-determination. Though the mere status as peoples and the right to self-determination, as for example in the case of Indigenous peoples (''peoples'', as in all groups of indigenous people, not merely all indigenous persons as in ''indigenous people''), does not automatically provide for independent sovereignty and therefore secession. Indeed, judge Ivor Jennings identified the inherent problems in the right of "peoples" to self-determination, as i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deep Brain Stimulation
Deep brain stimulation (DBS) is a type of neurostimulation therapy in which an implantable pulse generator is stereotactic surgery, surgically implanted subcutaneous tissue, below the skin of the chest and connected by Lead (electronics), leads to the brain to deliver controlled electrical charge, electrical impulses. These charges therapeutically disrupt and promote dysfunctional nervous system circuits bidirectionally in both ante- and retrograde signaling, retrograde directions. Though first developed for Parkinsonian tremor, the technology has since been adapted to a wide variety of chronic neurologic disorders. The usage of electrical stimulation to treat neurologic disorders dates back thousands of years to ancient Greece and Early Dynastic Period (Egypt), dynastic Egypt. The distinguishing feature of DBS, however, is that by taking advantage of the portability of lithium-ion battery technology, it is able to be used long term without the patient having to be Electrical wir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Botulinum Toxin
Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium ''Clostridium botulinum'' and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Botulinum toxin is an acetylcholine release inhibitor and a neuromuscular blocking agent. The seven main types of botulinum toxin are named types A to G (A, B, C1, C2, D, E, F and G). New types are occasionally found. Types A and B are capable of causing disease in humans, and are also used commercially and medically. Types C–G are less common; types E and F can cause disease in humans, while the other types cause disease in other animals. Botulinum toxins are among the most potent toxins known to science. Intoxication can occur naturally as a result of eithe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spasticity
Spasticity () is a feature of altered skeletal muscle performance with a combination of paralysis, increased tendon reflex activity, and hypertonia. It is also colloquially referred to as an unusual "tightness", stiffness, or "pull" of muscles. Clinically, spasticity results from the loss of inhibition of motor neurons, causing excessive velocity-dependent muscle contraction. This ultimately leads to hyperreflexia, an exaggerated deep tendon reflex. Spasticity is often treated with the drug baclofen, which acts as an agonist at GABA receptors, which are inhibitory. Spastic cerebral palsy is the most common form of cerebral palsy, which is a group of permanent movement problems that do not get worse over time. GABA's inhibitory actions contribute to baclofen's efficacy as an anti-spasticity agent. Pathophysiology Spasticity is usually caused by damage to nerve pathways within the brain or spinal cord that control muscle movement. This can cause an imbalance in the inhibitory ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tremor
A tremor is an involuntary, somewhat rhythmic muscle contraction and relaxation involving neural oscillations, oscillations or twitching movements of one or more body parts. It is the most common of all involuntary movements and can affect the hands, arms, eyes, face, head, vocal folds, trunk, and legs. Most tremors occur in the hands. In some people, a tremor is a symptom of another neurological disorder. Types Tremor is most commonly classified by clinical features and cause or origin. Some of the better-known forms of tremor, with their symptoms, include the following: * Cerebellar tremor (also known as intention tremor) is a slow, broad tremor of the extremities that occurs at the end of a purposeful movement, such as trying to press a button or touching a finger to the tip of one's nose. In classic cerebellar tremor, a lesion on one side of the brain produces a tremor in that same side of the body that worsens with directed movement. Cerebellar damage can also produce a "win ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cervical Dystonia
Spasmodic torticollis is an extremely painful chronic neurological movement disorder causing the neck to involuntarily turn to the left, right, upwards, and/or downwards. The condition is also referred to as "cervical dystonia". Both agonist and antagonist muscles contract simultaneously during dystonic movement. Causes of the disorder are predominantly idiopathic. A small number of patients develop the disorder as a result of another disorder or disease. Most patients first experience symptoms midlife. The most common treatment for spasmodic torticollis is the use of botulinum toxin type A. Signs and symptoms Initial symptoms of spasmodic torticollis are usually mild. Some feel an invisible tremor of their head for a few months at onset. Then the head may turn, pull or tilt in jerky movements, or sustain a prolonged position involuntarily. Over time, the involuntary spasm of the neck muscles will increase in frequency and strength until it reaches a plateau. Symptoms can also wor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
