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Daniel Von Hoff
Daniel D. Von Hoff is the physician in chief and director of translational research at Translational Genomics Research Institute (TGen), and current Virginia G. Piper Distinguished Chair for Innovative Cancer Research at HonorHealth Clinical Research Institute. He is also a professor of medicine at the Mayo Clinic and medical director of research as well as chief scientific officer at US Oncology. He is most notable for his work in targeted therapies for the treatment of cancer. He led the development of gemcitabine, and has several drugs in development. Education Von Hoff received his bachelor's degree from Carroll College, and his MD from Columbia University College of Physicians and Surgeons in 1973. He did a residency in internal medicine at UC San Francisco, followed by a fellowship in oncology at the National Cancer Institute. Career After his fellowship, Von Hoff joined the faculty at University of Texas Health Science Center, San Antonio (UTHSCSA) as a professor of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DVH Headshot
DVH may refer to *Darent Valley Hospital, an acute district general hospital in Dartford, Kent, England *Desert Valley Hospital *Dose-volume histogram *Dove Holes railway station, Derbyshire, England (National Rail station code) See also *DVHS (other) {{Disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Irinotecan
Irinotecan, sold under the brand name Camptosar among others, is an anti-cancer medication used to treat colon cancer and small cell lung cancer. For colon cancer it is used either alone or with fluorouracil. For small cell lung cancer it is used with cisplatin. It is given intravenously. Common side effects include diarrhea, vomiting, bone marrow suppression, hair loss, shortness of breath, and fever. Other severe side effects include blood clots, colon inflammation, and allergic reactions. Those with two copies of the UGT1A1*28 gene variant are at higher risk for side effects. Use during pregnancy can result in harm to the baby. Irinotecan is a topoisomerase inhibitor—it blocks the topoisomerase I enzyme, resulting in DNA damage and cell death. Irinotecan was approved for medical use in the United States in 1996. It is on the World Health Organization's List of Essential Medicines. It is made from the natural compound camptothecin which is found in the Chinese orn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of The AACR Academy
{{disambiguation ...
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places *Fellows, California, USA *Fellows, Wisconsin, ghost town, USA Other uses * Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton *Fellows (surname) *Mount Fellows, a mountain in Alaska See also *North Fellows Historic District, listed on the National Register of Historic Places in Wapello County, Iowa *Justice Fellows (other) Justice Fellows may refer to: * Grant Fellows (1865–1929), associate justice of the Michigan Supreme Court * Raymond Fellows (1885–1957), associate justice of the Maine Supreme Judicial Court {{disambiguation, tndis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Oncologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AACR Academy
The American Association for Cancer Research elects classes of fellows to recognize influential scientists in the field of cancer research. Six fellows were appointed to Vice President Biden’s Cancer Moonshot Initiative Blue Ribbon Panel. Several are members of the National Academy of Sciences, several have won a Lasker Award, several have won a Nobel Prize, several are HHMI The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization headquartered in Chevy Chase, Maryland with additional facilities in Ashburn, Virginia. It was founded in 1953 by Howard Hughes, an American busin ... Investigators, and several are past presidents of the AACR. References {{Reflist American oncologists Biology awards ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society Of Clinical Oncology
The American Society of Clinical Oncology (ASCO) is a professional organization representing physicians of all oncology sub-specialties who care for people with cancer. Founded in 1964 by Fred Ansfield, Harry Bisel, Herman Freckman, Arnoldus Goudsmit, Robert Talley, William Wilson, and Jane C. Wright, it has nearly 45,000 members worldwide. Physician education ASCO offers educational resources for cancer physicians and other health care professionals of clinical oncology. These include scientific meetings, educational conferences, professional workshops, and special symposia on issues of particular relevance and importance to oncologists and researchers. It also produced the patient information website, Cancer.Net. It publishes numerous journals, books, newsletters, and online and multimedia resources; it publishes the ''Journal of Clinical Oncology'' (JCO), the '' JCO Oncology Practice'' (JCO OP), and the ''JCO Global Oncology'' (JCO GO), '' JCO Clinical Cancer Informati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dana Farber Cancer Institute
Dana may refer to: Businesses and organisations * Dana (company), a Slovenian beverage company * Dana (payment service), in Indonesia * Dana Air, a Nigerian airline * Dana College, formerly in Nebraska, U.S. * Dana Energy, an Iranian oil and gas company * Dana Gas, a natural gas company Sharjah, United Arab Emirates * Dana Incorporated, an American auto parts firm * Dana Foundation, an American private philanthropic foundation * Dana Mall, in Manama, Bahrain * Dana Petroleum, a Scottish oil and gas exploration and production company * Dana Research Centre and Library, in London, England * House of Dana, a perfumery founded in 1932 People * Dana (given name), including a list of people and fictional characters with the given name * Dana (surname), including a list of people with the surname * Dana family, a Boston Brahmin family * James Dwight Dana (1813–1895), scientist, zoological author abbreviation Dana. * Dana Rosemary Scallon (born 1951), known mononymously as Dana, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For Cancer Research
The American Association for Cancer Research (AACR) is the world's oldest and largest professional association related to cancer research. Based in Philadelphia, the AACR focuses on all aspects of cancer research, including Basic research, basic, clinical, and translational research into the etiology (medicine), etiology, Preventive medicine, prevention, diagnosis, and therapy, treatment of cancer. Founded in 1907 by 11 physicians and scientists, the organization now has more than 58,000 members in 142 countries and territories. The mission of the AACR is to prevent and cure cancer through research, education, communication, collaboration, science policy and advocacy, and funding for cancer research. History The AACR was founded on May 7, 1907, in Washington, D.C., as the "Association for Cancer Research" by a group of scientists consisting of four surgeons, five pathologists, and two biochemists. The founding members were Silas P. Beebe, George H. A. Clowes, William Coley, Jame ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is a United States–based international nonprofit with the stated mission of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting science education, scientific education and science outreach for the betterment of all humanity. AAAS was the first permanent organization established to promote science and engineering nationally and to represent the interests of American researchers from across all scientific fields. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science (journal), Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists with the broaden ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American College Of Physicians
The American College of Physicians (ACP) is a Philadelphia-based national organization of internal medicine physicians, who specialize in the diagnosis, treatment, and care of adults. With 161,000 members, ACP is the largest medical-specialty organization and second-largest physician group in the United States.Osmosis "Prep for the Medicine Shelf". Retrieved October 20, 2014 Its flagship journal, the ''Annals of Internal Medicine'', is among the most widely cited peer-reviewed medical journals in the world. History ACP was founded in 1915 to promote the science and practice of medicine. In 1998, it merged with the American Society of Internal Medicine (ASIM). ASIM's focus on the economic, political, and social aspects of medical care both enlarged and complemented its mission. Known as ACP-ASIM from 1998 to 2003, the organization re-adopted "American College of Physicians" as its corporate name from 2003 on.Philadelphia Business Journal "Health Care" Retrieved October 20, 2014 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vismodegib
Vismodegib, sold under the brand name Erivedge, is a medication used for the treatment of basal-cell carcinoma (BCC). The approval of vismodegib on January 30, 2012, represents the first Hedgehog signaling pathway targeting agent to gain U.S. Food and Drug Administration (FDA) approval. The drug is also undergoing clinical trials for metastatic colorectal cancer, small-cell lung cancer, advanced stomach cancer, pancreatic cancer, medulloblastoma and chondrosarcoma . The drug was developed by the biotechnology/pharmaceutical company Genentech. Indication Vismodegib is indicated for people with basal-cell carcinoma (BCC) which has metastasized to other parts of the body, relapsed after surgery, or cannot be treated with surgery or radiation. Mechanism of action The substance acts as a cyclopamine-competitive antagonist of the smoothened receptor (SMO) which is part of the Hedgehog signaling pathway. SMO inhibition causes the transcription factors GLI1 and GLI2 to remain inactiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
