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DEXA
Dual-energy X-ray absorptiometry (DXA, or DEXA) is a means of measuring bone mineral density (BMD) with spectral imaging. Two X-ray beams, with different energy levels, are aimed at the patient's bones. When soft tissue absorption is subtracted, the bone mineral density (BMD) can be determined from the absorption of each beam by bone. Dual-energy X-ray absorptiometry is the most widely used and most thoroughly studied bone density measurement technology. The DXA scan is typically used to diagnose and follow osteoporosis, as contrasted to the nuclear bone scan, which is sensitive to certain metabolic diseases of bones in which bones are trying to heal from infections, fractures, or tumors. It is also sometimes used to assess body composition. Physics Soft tissue and bone have different attenuation coefficients to X-rays. A single X-ray beam passing through the body is attenuated by both soft tissue and bone, and it is not possible to determine from a single beam how much attenu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Body Composition
In physical fitness, body composition refers to quantifying the different components (or "compartments") of a human body. The selection of compartments varies by model but may include fat, bone, water, and muscle. Two people of the same gender, height, and body weight may have completely different body types as a consequence of having different body compositions. This may be explained by a person having low or high body fat, dense muscles, or big bones. Compartment models Body composition models typically use between 2 and 6 compartments to describe the body. Common models include: * 2 compartment: Fat mass (FM) and fat-free mass (FFM) * 3 compartment: Fat mass (FM), water, and fat-free dry mass * 4 compartment: Fat mass (FM), water, protein, and mineral * 5 compartment: Fat mass (FM), water, protein, bone mineral content, and non-osseous mineral content * 6 compartment: Fat mass (FM), water, protein, bone mineral content, non-osseous mineral content, and glycogen As a rule, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bone
A bone is a rigid organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility. Bones come in a variety of shapes and sizes and have complex internal and external structures. They are lightweight yet strong and hard and serve multiple functions. Bone tissue (osseous tissue), which is also called bone in the uncountable sense of that word, is hard tissue, a type of specialised connective tissue. It has a honeycomb-like matrix internally, which helps to give the bone rigidity. Bone tissue is made up of different types of bone cells. Osteoblasts and osteocytes are involved in the formation and mineralisation of bone; osteoclasts are involved in the resorption of bone tissue. Modified (flattened) osteoblasts become the lining cells that form a protective layer on the bone surface. The mine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osteoporosis
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in Bone fracture, fracture risk. It is the most common reason for a broken bone among the Old age, elderly. Bones that commonly break include the vertebrae in the Vertebral column, spine, the bones of the forearm, the wrist, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor stress or spontaneously. After the broken bone heals, some people may have chronic pain and a decreased ability to carry out normal activities. Osteoporosis may be due to lower-than-normal peak bone mass, maximum bone mass and greater-than-normal bone loss. Bone loss increases after menopause in women due to lower levels of estrogen, and after andropause in older men due to lower levels of testosterone. Osteoporosis may also occur due to a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bone Mineral Density
Bone density, or bone mineral density, is the amount of bone mineral in bone tissue. The concept is of mass of mineral per volume of bone (relating to density in the physics sense), although clinically it is measured by proxy according to optical density per square centimetre of bone surface upon imaging. Bone density measurement is used in clinical medicine as an indirect indicator of osteoporosis and fracture risk. It is measured by a procedure called densitometry, often performed in the radiology or nuclear medicine departments of hospitals or clinics. The measurement is painless and non-invasive and involves low radiation exposure. Measurements are most commonly made over the lumbar spine and over the upper part of the hip. The forearm may be scanned if the hip and lumbar spine are not accessible. There is a statistical association between poor bone density and higher probability of fracture. Fractures of the legs and pelvis due to falls are a significant public health p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osteopenia
Osteopenia, known as "low bone mass" or "low bone density", is a condition in which bone mineral density is low. Because their bones are weaker, people with osteopenia may have a higher risk of fractures, and some people may go on to develop osteoporosis. In 2010, 43 million older adults in the US had osteopenia. Unlike osteoporosis, osteopenia does not usually cause symptoms, and losing bone density in itself does not cause pain. There is no single cause for osteopenia, although there are several risk factors, including modifiable (behavioral, including dietary and use of certain drugs) and non-modifiable (for instance, loss of bone mass with age). For people with risk factors, screening via a DXA scanner may help to detect the development and progression of low bone density. Prevention of low bone density may begin early in life and includes a healthy diet and weight-bearing exercise, as well as avoidance of tobacco and alcohol. The treatment of osteopenia is controversial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bone Density
Bone density, or bone mineral density, is the amount of bone mineral in bone tissue. The concept is of mass of mineral per volume of bone (relating to density in the physics sense), although medicine#Clinical practice, clinically it is measured by proxy according to optical density per square centimetre of bone surface upon medical imaging, imaging. Bone density measurement is used in clinical medicine as an indirect indicator of osteoporosis and fracture risk. It is measured by a procedure called densitometry, often performed in the radiology or nuclear medicine departments of hospitals or clinics. The measurement is painless and non-invasive and involves low radiation exposure. Measurements are most commonly made over the lumbar spine and over the upper part of the hip. The forearm may be scanned if the hip and lumbar spine are not accessible. There is a statistics, statistical association between poor bone density and higher probability of fracture. Fractures of the legs and pel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ABIM Foundation
Choosing Wisely is a United States–based health educational campaign, led by the ABIM Foundation ( American Board of Internal Medicine), about unnecessary health care. The campaign identifies over 500 tests and procedures and encourages doctors and patients to discuss, research, and possibly get second opinions, before proceeding with them. To conduct the campaign, the ABIM Foundation asks medical specialty societies to make five to ten recommendations for preventing overuse of a treatment in their field. The foundation then publicizes this information, and the medical specialty societies disseminate it to their members. The campaign has garnered both praise and criticism, and some of its ideas have spread to other countries. It does not include evaluation of its effects on costs, on discussions or on medical outcomes. Some doctors have said they lack time for the recommended discussions. History In 2002 the ABIM Foundation published ''Medical professionalism in the new mill ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FRAX
FRAX (fracture risk assessment tool) is a diagnostic tool used to evaluate the 10-year probability of bone fracture risk. It was developed by the University of Sheffield. FRAX integrates clinical risk factors and bone mineral density at the femoral neck to calculate the 10-year probability of hip fracture and the 10-year probability of a major osteoporotic fracture (clinical spine, forearm, hip or shoulder fracture). The models used to develop the FRAX diagnostic tool were derived from studying patient populations in North America, Europe, Latin America, Asia and Australia. Components The parameters included in a FRAX assessment are: *Country *Age *Sex *Weight *Height *Previous fracture *Hip fracture in the subject's mother or father *Smoking *Glucocorticoid treatment *Rheumatoid arthritis *Disease strongly associated with osteoporosis *Alcohol intake of three or more standard drinks per day *Bone mineral density (BMD) of the femoral neck *Trabecular bone score (optional) Avail ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucocorticoids
Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. The name "glucocorticoid" is a portmanteau of "glucose", "cortex", and "steroid" and is composed from its role in regulation of glucose metabolism, synthesis in the adrenal cortex, and its steroidal structure (see structure below). Glucocorticoids are part of the feedback mechanism in the immune system, which reduces certain aspects of immune function, such as inflammation. They are therefore used in medicine to treat diseases caused by an overactive immune system, such as allergies, asthma, autoimmune diseases, and sepsis. Glucocorticoids have many diverse effects such as pleiotropy, including potentially harmful side effects. They also interfere with some of the abnormal mechanisms in cancer cells, so they are used in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morbus Fabry DXA 01
''Teenage Mutant Ninja Turtles'' (''TMNT'') is an American media franchise created by comic book artists Kevin Eastman and Peter Laird. It follows Leonardo (Teenage Mutant Ninja Turtles), Leonardo, Donatello (Teenage Mutant Ninja Turtles), Donatello, Raphael (Teenage Mutant Ninja Turtles), Raphael and Michelangelo (Teenage Mutant Ninja Turtles), Michelangelo, four Anthropomorphism, anthropomorphic turtle brothers trained in ''ninjutsu'' who fight evil in New York City. The franchise encompasses printed media, television series, feature films, video games, and merchandise. The franchise began as a comic book, ''Teenage Mutant Ninja Turtles (Mirage Studios), Teenage Mutant Ninja Turtles'', which Eastman and Laird conceived as a parody of elements popular in superhero comics at the time. The first issue was published in 1984 by Eastman and Laird's company Mirage Studios and was a surprise success. In 1987, Eastman and Laird licensed the characters to Playmates Toys, which develo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mass
Mass is an Intrinsic and extrinsic properties, intrinsic property of a physical body, body. It was traditionally believed to be related to the physical quantity, quantity of matter in a body, until the discovery of the atom and particle physics. It was found that different atoms and different elementary particle, elementary particles, theoretically with the same amount of matter, have nonetheless different masses. Mass in modern physics has multiple Mass in special relativity, definitions which are conceptually distinct, but physically equivalent. Mass can be experimentally defined as a measure (mathematics), measure of the body's inertia, meaning the resistance to acceleration (change of velocity) when a net force is applied. The object's mass also determines the Force, strength of its gravitational attraction to other bodies. The SI base unit of mass is the kilogram (kg). In physics, mass is Mass versus weight, not the same as weight, even though mass is often determined by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Z-score
In statistics, the standard score or ''z''-score is the number of standard deviations by which the value of a raw score (i.e., an observed value or data point) is above or below the mean value of what is being observed or measured. Raw scores above the mean have positive standard scores, while those below the mean have negative standard scores. It is calculated by subtracting the population mean from an individual raw score and then dividing the difference by the population standard deviation. This process of converting a raw score into a standard score is called standardizing or normalizing (however, "normalizing" can refer to many types of ratios; see ''Normalization'' for more). Standard scores are most commonly called ''z''-scores; the two terms may be used interchangeably, as they are in this article. Other equivalent terms in use include z-value, z-statistic, normal score, standardized variable and pull in high energy physics. Computing a z-score requires knowledge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
