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Croton Lechleri
''Croton lechleri'' is a species of flowering plant in the spurge family, Euphorbiaceae, that is native to northwestern South America. It is commonly known as ''sangre de grado'' (Peruvian Spanish), ''sangre de drago'' (Ecuadorian Spanish) or ''sangre de grada'' (Bolivian Spanish).Meza, E.N.(Editor). 1999. They refer to this tree's (and several related species') thick red latex. The latex has medicinal properties, and is used by local peoples as a liquid bandage, applied to seal wounds, as it dries quickly to form a protective skin-like barrier. Its use by native people has led to scientific study and observation of its ''in vitro'' antioxidant activity as well as both mutagenic and antimutagenic behavior. The latex also contains a number of chemicals, including taspine. Oligomeric proanthocyanidins, another kind of chemical contained in the latex, have been investigated for the treatment of HIV-associated diarrhea under the name crofelemer. In January 2013, crofelemer, u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jatropha Dioica
''Jatropha dioica'' is a species of flowering plant in the spurge family, Euphorbiaceae, that is native to an area from Texas in the United States to as far south as Oaxaca in Mexico. Common names include leatherstem and sangre de drago. The specific name refers to the dioecious nature of the plants. Description ''Jatropha dioica'' forms colonies from subterranean rhizomes. The arching, succulent stems reach a height of 20–60 cm and have few branches. They are tough and sufficiently flexible to be tied into overhand knots without breaking. The orange rootstock spreads to a length of around 1 m. Leaves are arranged simply, alternately, or fascicularly and are clustered on short shoots extending from the stems. They are subsessile and have entire margins. The leaves of the nominate variety are linear and measure up to 6 × 1 cm, whereas the leaves of ''J. dioica'' var. ''graminea'' may be 2 to 3-lobed and measure up to 6.5 × 0.5 cm. Male inflorescences are cluste ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amazon Basin
The Amazon basin is the part of South America drained by the Amazon River and its tributary, tributaries. The Amazon drainage basin covers an area of about , or about 35.5 percent of the South American continent. It is located in the countries of Bolivia, Brazil, Colombia, Ecuador, Guyana, Peru, Suriname, and Venezuela, as well as the territory of French Guiana. Most of the basin is covered by the Amazon rainforest, also known as Amazon rainforest, Amazonia. With a area of dense tropical forest, it is the largest rainforest in the world. Geography The Amazon River begins in the Andes, Andes Mountains at the west of the basin with its main tributary the Marañón River and Apurímac River, Apurimac River in Peru. The highest point in the Drainage divide, watershed of the Amazon is the second biggest peak of Yerupajá at . The Amazon River Basin occupies the entire central and eastern area of South America, lying to the east of the Andes mountain range and extending from th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trichophyton
''Trichophyton'' is a genus Genus (; : genera ) is a taxonomic rank above species and below family (taxonomy), family as used in the biological classification of extant taxon, living and fossil organisms as well as Virus classification#ICTV classification, viruses. In bino ... of fungus, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-walled macro- and microconidia. Macroconidia are mostly borne laterally directly on the hyphae or on short pedicels, and are thin- or thick-walled, clavate to fusiform, and range from 4 to 8 by 8 to 50 μm in size. Macroconidia are few or absent in many species. Microconidia are spherical, pyriform to clavate or of irregular shape, and range from 2 to 3 by 2 to 4 μm in size. Species and their habitat preference According to current classificati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemotaxis
Chemotaxis (from ''chemical substance, chemo-'' + ''taxis'') is the movement of an organism or entity in response to a chemical stimulus. Somatic cells, bacteria, and other single-cell organism, single-cell or multicellular organisms direct their movements according to certain chemicals in their environment. This is important for bacteria to find food (e.g., glucose) by swimming toward the highest concentration of food molecules, or to flee from poisons (e.g., phenol). In multicellular organisms, chemotaxis is critical to early development (e.g., movement of sperm towards the egg during fertilization) and development (e.g., migration of neurons or lymphocytes) as well as in normal function and health (e.g., migration of White blood cell, leukocytes during injury or infection). In addition, it has been recognized that mechanisms that allow chemotaxis in animals can be subverted during cancer metastasis, and the aberrant change of the overall property of these networks, which contro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Taspine
Taspine is an alkaloid which acts as a potent acetylcholinesterase inhibitor and cicatrizant. It is found in various plants including '' Magnolia x soulangeana'' and ''Croton lechleri ''Croton lechleri'' is a species of flowering plant in the spurge family, Euphorbiaceae, that is native to northwestern South America. It is commonly known as ''sangre de grado'' (Peruvian Spanish), ''sangre de drago'' (Ecuadorian Spanish) or ' ...''. The first total synthesis was reported by T. Ross Kelly and Roger L. Xie in 1998. References Acetylcholinesterase inhibitors Alkaloids found in Euphorbiaceae Phenethylamine alkaloids Lactones Dimethylamino compounds Heterocyclic compounds with 4 rings Phenol ethers Methoxy compounds Total synthesis {{Alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. It can be taken by mouth or intravenously. Malaria resistance to quinine occurs in certain areas of the world. Quinine is also used as an ingredient in tonic water and other beverages to impart a bitter taste. Common side effects include headache, tinnitus, ringing in the ears, vision issues, and sweating. More severe side effects include deafness, thrombocytopenia, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy carries potential for fetal harm, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an alkaloid, a natural ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jesuit's Bark
Jesuit's bark, also known as cinchona bark, Peruvian bark or China bark, is a former remedy for malaria, as the bark contains quinine, used to treat the disease. The bark of several species of the genus ''Cinchona'', family Rubiaceae indigenous to the western Andes of South America, was introduced to Jesuit missionaries during the 17th century as a traditional treatment for malaria by indigenous people in Peru. History The postcolonial history of cinchona bark dates back more than 350 years. Circa 1650, the physician Sebastiano Bado declared that this bark had proved more precious to mankind than all the gold and silver that the Spaniards had obtained from South America. In the 18th century, the Italian professor of medicine Bernardino Ramazzini said that the introduction of Peruvian bark would be of the same importance to medicine that the discovery of gunpowder was to the art of war, an opinion endorsed by contemporary writers on the history of medicine. The value of Jesuit's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cinchona
''Cinchona'' (pronounced or ) is a genus of flowering plants in the family Rubiaceae containing at least 23 species of trees and shrubs. All are native to the Tropical Andes, tropical Andean forests of western South America. A few species are reportedly naturalization (biology), naturalized in Central America, Jamaica, French Polynesia, Sulawesi, Saint Helena in the South Atlantic, and São Tomé and Príncipe off the coast of tropical Africa, and others have been cultivated in India and Java, where they have formed hybrids. ''Cinchona'' has been historically sought after for its medicinal value, as the bark of several species yields quinine and other alkaloids. These were the only effective treatments against malaria during the height of European colonialism, which made them of great economic and political importance. Trees in the genus are also known as fever trees because of their antimalarial properties. The artificial Quinine total synthesis, synthesis of quinine in 1944, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bernabé Cobo
Bernabé Cobo (born at Lopera in Spain, 1582; died at Lima, Peru, 9 October 1657) was a Spanish Jesuit missionary and writer. He played a part in the early history of quinine by his description of cinchona bark; he brought some to Europe on a visit in 1632. He was a thorough student of nature and man in Spanish America. His long residence (61 years), his position as a priest and, several times, as a missionary, gave him unusual opportunities for obtaining reliable information. The Spanish botanist Cavanilles gave the name of '' Cobaea'' to a genus of plants belonging to the Polemoniaceae of Mexico, '' Cobaea scandens'' being its most striking representative. Life He went to America in 1596, visiting the Antilles and Venezuela and landing at Lima in 1599. Entering the Society of Jesus, 14 October 1601, he was sent by his superiors in 1615 to the mission of Juli, where, and at Potosí, Cochabamba, Oruro, and La Paz, he laboured until 1618. He was rector of the college of Ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Venezuela
Venezuela, officially the Bolivarian Republic of Venezuela, is a country on the northern coast of South America, consisting of a continental landmass and many Federal Dependencies of Venezuela, islands and islets in the Caribbean Sea. It comprises an area of , and its population was estimated at 29 million in 2022. The capital and largest urban agglomeration is the city of Caracas. The continental territory is bordered on the north by the Caribbean Sea and the Atlantic Ocean, on the west by Colombia, Brazil on the south, Trinidad and Tobago to the north-east and on the east by Guyana. Venezuela is a presidential republic consisting of States of Venezuela, 23 states, the Venezuelan Capital District, Capital District and Federal Dependencies of Venezuela, federal dependencies covering Venezuela's offshore islands. Venezuela is among the most urbanized countries in Latin America; the vast majority of Venezuelans live in the cities of the north and in the capital. The territory o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peru
Peru, officially the Republic of Peru, is a country in western South America. It is bordered in the north by Ecuador and Colombia, in the east by Brazil, in the southeast by Bolivia, in the south by Chile, and in the south and west by the Pacific Ocean. Peru is a Megadiverse countries, megadiverse country, with habitats ranging from the arid plains of the Pacific coastal region in the west, to the peaks of the Andes mountains extending from the north to the southeast of the country, to the tropical Amazon basin rainforest in the east with the Amazon River. Peru has Demographics of Peru, a population of over 32 million, and its capital and largest city is Lima. At , Peru is the List of countries and dependencies by area, 19th largest country in the world, and the List of South American countries by area, third largest in South America. Pre-Columbian Peru, Peruvian territory was home to Andean civilizations, several cultures during the ancient and medieval periods, and has one o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ecuador
Ecuador, officially the Republic of Ecuador, is a country in northwestern South America, bordered by Colombia on the north, Peru on the east and south, and the Pacific Ocean on the west. It also includes the Galápagos Province which contains the Galapagos Islands in the Pacific, about west of the mainland. The country's Capital city, capital is Quito and its largest city is Guayaquil. The land that comprises modern-day Ecuador was once home to several groups of Indigenous peoples in Ecuador, indigenous peoples that were gradually incorporated into the Inca Empire during the 15th century. The territory was Spanish colonization of the Americas, colonized by the Spanish Empire during the 16th century, achieving independence in 1820 as part of Gran Colombia, from which it emerged as a sovereign state in 1830. The legacy of both empires is reflected in Ecuador's ethnically diverse population, with most of its million people being mestizos, followed by large minorities of Europe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
