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Cinchona
''Cinchona'' (pronounced or ) is a genus of flowering plants in the family Rubiaceae containing at least 23 species of trees and shrubs. All are native to the tropical Andean forests of western South America. A few species are reportedly naturalized in Central America, Jamaica, French Polynesia, Sulawesi, Saint Helena in the South Atlantic, and São Tomé and Príncipe off the coast of tropical Africa, and others have been cultivated in India and Java, where they have formed hybrids. ''Cinchona'' has been historically sought after for its medicinal value, as the bark of several species yields quinine and other alkaloids. These were the only effective treatments against malaria during the height of European colonialism, which made them of great economic and political importance. Trees in the genus are also known as fever trees because of their anti-malarial properties. The artificial synthesis of quinine in 1944, an increase in resistant forms of malaria, and the emergence of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to '' Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. It can be taken by mouth or intravenously. Malaria resistance to quinine occurs in certain areas of the world. Quinine is also used as an ingredient in tonic water to impart a bitter taste. Common side effects include headache, ringing in the ears, vision issues, and sweating. More severe side effects include deafness, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy causes harm to the baby, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an alkaloid, a naturally occurring chemical compound. How it works as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clements Markham
Sir Clements Robert Markham (20 July 1830 – 30 January 1916) was an English geographer, explorer and writer. He was secretary of the Royal Geographical Society (RGS) between 1863 and 1888, and later served as the Society's president for a further 12 years. In the latter capacity he was mainly responsible for organising the British National Antarctic Expedition of 1901–1904, and for launching the polar career of Robert Falcon Scott. Markham began his career as a Royal Navy cadet and midshipman, during which time he went to the Arctic with in one of the many searches for Franklin's lost expedition. Later, Markham served as a geographer to the India Office, and was responsible for the collection of cinchona plants from their native Peruvian forests, and their transplantation in India. By this means, the Indian government acquired a home source from which quinine could be extracted. Markham also served as geographer to Sir Robert Napier's Abyssinian expeditionary fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jesuit's Bark
Jesuit's bark, also known as cinchona bark, Peruvian bark or China bark, is a former remedy for malaria, as the bark contains quinine used to treat the disease. The bark of several species of the genus ''Cinchona'', family Rubiaceae indigenous to the western Andes of South America, was discovered as a folk medicine treatment for malaria by Jesuit missionaries in Peru during the 17th century. History The western history of cinchona bark dates back more than 350 years. Circa 1650, the physician Sebastiano Bado declared that this bark had proved more precious to mankind than all the gold and silver that the Spaniards had obtained from South America. In the 18th century, the Italian professor of medicine Bernardino Ramazzini said that the introduction of Peruvian bark would be of the same importance to medicine that the discovery of gunpowder was to the art of war, an opinion endorsed by contemporary writers on the history of medicine. The value of Jesuit's bark, and the controve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the '' Plasmodium'' group. It is spread exclusively through bites of infected '' Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a class of basic BASIC (Beginners' All-purpose Symbolic Instruction Code) is a family of general-purpose, high-level programming languages designed for ease of use. The original version was created by John G. Kemeny and Thomas E. Kurtz at Dartmouth College ..., natural product, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms includi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tree
In botany, a tree is a perennial plant with an elongated stem, or trunk, usually supporting branches and leaves. In some usages, the definition of a tree may be narrower, including only woody plants with secondary growth, plants that are usable as lumber or plants above a specified height. In wider definitions, the taller palms, tree ferns, bananas, and bamboos are also trees. Trees are not a taxonomic group but include a variety of plant species that have independently evolved a trunk and branches as a way to tower above other plants to compete for sunlight. The majority of tree species are angiosperms or hardwoods; of the rest, many are gymnosperms or softwoods. Trees tend to be long-lived, some reaching several thousand years old. Trees have been in existence for 370 million years. It is estimated that there are some three trillion mature trees in the world. A tree typically has many secondary branches supported clear of the ground by the trunk. This trunk typi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luis Jerónimo De Cabrera, 4th Count Of Chinchón
Luis Jerónimo Fernández de Cabrera Bobadilla Cerda y Mendoza, 4th Count of Chinchón, also known as Luis Xerónimo Fernandes de Cabrera Bobadilla y Mendoza, (1589 in Madrid – October 28, 1647 in Madrid) was a Spanish nobleman, Comendador of Criptana, Alcaide of the Alcázar de Segovia, Treasurer of Aragón, and captain general and Viceroy of Peru, from January 14, 1629, to December 18, 1639. His wife, Ana de Osorio (1599–1625), is credited as being one of the first Europeans to be treated with quinine, and as the person who introduced that medicine into Europe. Birth Fernández de Cabrera Bobadilla was born in Madrid in 1589 (or perhaps 1590), into a family close to the Spanish throne. His parents were Diego Fernández de Cabrera, third Count of Chinchón and Inés Pacheco, the daughter of the marquis of Villena and 3rd Duke of Escalona, Diego López Pacheco, and Luisa Bernarda de Cabrera Bobadilla, third marquesa of Moya. Don Luis's parents were first cousins. He was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of National Trees ...
This is a list of national trees, most official, but some unofficial. National trees See also * National emblem * Floral emblem * List of U.S. State and territory trees References {{DEFAULTSORT:List Of National Trees N Trees In botany, a tree is a perennial plant with an elongated stem, or trunk, usually supporting branches and leaves. In some usages, the definition of a tree may be narrower, including only woody plants with secondary growth, plants that are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinine Total Synthesis
The total synthesis of quinine, a naturally-occurring antimalarial drug, was developed over a 150-year period. The development of synthetic quinine is considered a milestone in organic chemistry although it has never been produced industrially as a substitute for natural occurring quinine. The subject has also been attended with some controversy: Gilbert Stork published the first stereoselective total synthesis of quinine in 2001, meanwhile shedding doubt on the earlier claim by Robert Burns Woodward and William Doering in 1944, claiming that the final steps required to convert their last synthetic intermediate, quinotoxine, into quinine would not have worked had Woodward and Doering attempted to perform the experiment. A 2001 editorial published in ''Chemical & Engineering News'' sided with Stork, but the controversy was eventually laid to rest once and for all when Williams and coworkers successfully repeated Woodward's proposed conversion of quinotoxine to quinine in 2007. Ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leaf
A leaf (plural, : leaves) is any of the principal appendages of a vascular plant plant stem, stem, usually borne laterally aboveground and specialized for photosynthesis. Leaves are collectively called foliage, as in "autumn foliage", while the leaves, stem, flower, and fruit collectively form the shoot system. In most leaves, the primary photosynthesis, photosynthetic tissue is the palisade mesophyll and is located on the upper side of the blade or lamina of the leaf but in some species, including the mature foliage of ''Eucalyptus'', palisade mesophyll is present on both sides and the leaves are said to be isobilateral. Most leaves are flattened and have distinct upper (Glossary of botanical terms#adaxial, adaxial) and lower (Glossary of botanical terms#abaxial, abaxial) surfaces that differ in color, hairiness, the number of stomata (pores that intake and output gases), the amount and structure of epicuticular wax and other features. Leaves are mostly green in color due ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evergreen
In botany, an evergreen is a plant which has foliage that remains green and functional through more than one growing season. This also pertains to plants that retain their foliage only in warm climates, and contrasts with deciduous plants, which completely lose their foliage during the winter or dry season. Evergreen species There are many different kinds of evergreen plants, both trees and shrubs. Evergreens include: *Most species of conifers (e.g., pine, hemlock, blue spruce, and red cedar), but not all (e.g., larch) * Live oak, holly, and "ancient" gymnosperms such as cycads *Most angiosperms from frost-free climates, and rainforest trees *All Eucalypts * Clubmosses and relatives *Bamboos The Latin binomial term , meaning "always green", refers to the evergreen nature of the plant, for instance :'' Cupressus sempervirens'' (a cypress) :'' Lonicera sempervirens'' (a honeysuckle) :'' Sequoia sempervirens'' (a sequoia) Leaf longevity in evergreen plants varies from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shrub
A shrub (often also called a bush) is a small-to-medium-sized perennial woody plant. Unlike herbaceous plants, shrubs have persistent woody stems above the ground. Shrubs can be either deciduous or evergreen. They are distinguished from trees by their multiple stems and shorter height, less than tall. Small shrubs, less than 2 m (6.6 ft) tall are sometimes termed as subshrubs. Many botanical groups have species that are shrubs, and others that are trees and herbaceous plants instead. Some definitions state that a shrub is less than and a tree is over 6 m. Others use as the cut-off point for classification. Many species of tree may not reach this mature height because of hostile less than ideal growing conditions, and resemble a shrub-sized plant. However, such species have the potential to grow taller under the ideal growing conditions for that plant. In terms of longevity, most shrubs fit in a class between perennials and trees; some may only last about fiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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