Taspine
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Taspine is an
alkaloid Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large varie ...
which acts as a potent
acetylcholinesterase inhibitor Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, thereby increasing both the level an ...
and cicatrizant. It is found in various plants including '' Magnolia x soulangeana'' and ''
Croton lechleri ''Croton lechleri'' is a species of flowering plant in the spurge family, Euphorbiaceae, that is native to northwestern South America. It is commonly known as ''sangre de grado'' (Peruvian Spanish), ''sangre de drago'' (Ecuadorian Spanish) or ' ...
''. The first total synthesis was reported by T. Ross Kelly and Roger L. Xie in 1998.


References

Acetylcholinesterase inhibitors Alkaloids found in Euphorbiaceae Phenethylamine alkaloids Lactones Dimethylamino compounds Heterocyclic compounds with 4 rings Phenol ethers Methoxy compounds Total synthesis {{Alkaloid-stub