Taspine is an
alkaloid
Alkaloids are a class of basic
BASIC (Beginners' All-purpose Symbolic Instruction Code) is a family of general-purpose, high-level programming languages designed for ease of use. The original version was created by John G. Kemeny and Th ...
which acts as a potent
acetylcholinesterase inhibitor
Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, thereby increasing both the level and ...
and
cicatrizant
D03A Cicatrizants
D03AA Cod-liver oil ointments
D03AX Other cicatrizants
:D03AX01 Cadexomer iodine
:D03AX02 Dextranomer
:D03AX03 Dexpanthenol
:D03AX04 Calcium pantothenate
:D03AX05 Hyaluronic acid
:D03AX06 Becaplermin
:D03AX09 Crilanomer
...
. It is found in various plants including ''
Magnolia x soulangeana'' and ''
Croton lechleri
''Croton lechleri'' is a species of flowering plant in the spurge family, Euphorbiaceae, that is native to northwestern South America. It is commonly known as ''sangre de grado'' (Peruvian Spanish), ''sangre de drago'' (Ecuadorian Spanish) or ' ...
''.
The first total synthesis was reported by T. Ross Kelly and Roger L. Xie in 1998.
References
Acetylcholinesterase inhibitors
Alkaloids found in Euphorbiaceae
Phenethylamine alkaloids
Lactones
Dimethylamino compounds
{{Alkaloid-stub