|
Coiled-coil Domain-containing 37 (FLJ40083)
Coiled-coil domain-containing 37, also known as FLJ40083, is a protein that in humans is encoded by the ''CCDC37'' gene (3q21.3). There is no confirmed function of CCDC37. Gene Locus The human gene CCDC37 is found on chromosome 3 at the band 3q21.3. It extends from base pairs 90,403,731 to 90,429,231, making the gene 25,500 base pairs long. It is located on the plus strand and contains 17 exons. Homology Paralogs :There is only one paralog for CCDC37 found in humans, CCDC38. CCDC38 is located on chromosome 12. Orthologs The ortholog space of CCDC37 is fairly broad including mammals, reptiles, birds, amphibians, fish, invertebrates, and fungi. Protein Primary sequence The gene encodes a protein called CCDC37. This protein in 611 amino acids in length and has a molecular weight of 71.1 kilodaltons and an isoelectric point of pI=6.7. Domains CCDC37 contains a DUF4200 region located from amino acid 151 to 269. There is no known function for DUF4200. CCDC37 also contains three ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Python Bivittatus
The Burmese python (''Python bivittatus'') is one of the largest species of snakes. It is native to a large area of Southeast Asia and is listed as Vulnerable on the IUCN Red List. Until 2009, it was considered a subspecies of the Indian python, but is now recognized as a distinct species. It is an invasive species in Florida as a result of the pet trade. Description The Burmese python is a dark-colored non-venomous snake with many brown blotches bordered by black down the back. In the wild, Burmese pythons typically grow to , while specimens of more than are unconfirmed. This species is sexually dimorphic in size; females average only slightly longer, but are considerably heavier and bulkier than the males. For example, length-weight comparisons in captive Burmese pythons for individual females have shown: at length, a specimen weighed , a specimen of just over weighed , a specimen of weighed , and a specimen of weighed . In comparison, length-weight comparisons for males ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oligodendrocyte
Oligodendrocytes (), also known as oligodendroglia, are a type of neuroglia whose main function is to provide the myelin sheath to neuronal axons in the central nervous system (CNS). Myelination gives metabolic support to, and insulates the axons of most vertebrates. A single oligodendrocyte can extend its Cellular extensions, processes to cover up to 40 axons, that can include multiple adjacent axons. The myelin sheath is segmented along the axon's length at gaps known as the nodes of Ranvier. In the peripheral nervous system the myelination of axons is carried out by Schwann cells. Oligodendrocytes are found exclusively in the CNS, which comprises the brain and spinal cord. They are the most widespread cell lineage, including oligodendrocyte progenitor cells, pre-myelinating cells, and mature myelinating oligodendrocytes in the CNS white matter. Non-myelinating oligodendrocytes are found in the grey matter surrounding and lying next to neuronal cell bodies. They are known as neu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rattus Norvegicus
''Rattus'' is a genus of muroid rodents, all typically called rats. However, the term rat can also be applied to rodent species outside of this genus. Species and description The best-known ''Rattus'' species are the black rat (''R. rattus'') and the brown rat (''R. norvegicus''). The group is generally known as the Old World rats or true rats and originated in Asia. Rats are bigger than most Old World mice, which are their relatives, but seldom weigh over in the wild. Taxonomy of ''Rattus'' The genus ''Rattus'' is a member of the giant subfamily Murinae. Several other murine genera are sometimes considered part of ''Rattus'': ''Lenothrix'', '' Anonymomys'', '' Sundamys'', '' Kadarsanomys'', '' Diplothrix'', '' Margaretamys'', '' Lenomys'', '' Komodomys'', '' Palawanomys'', '' Bunomys'', ''Nesoromys'', ''Stenomys'', '' Taeromys'', '' Paruromys'', '' Abditomys'', '' Tryphomys'', '' Limnomys'', '' Tarsomys'', '' Bullimus'', '' Apomys'', '' Millardia'', '' Srilankamys'', '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mouse Brain
A mouse (: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus''). Mice are also popular as pets. In some places, certain kinds of Apodemus, field mice are locally common. They are known to invade homes for food and shelter. Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term ''mouse'' if it is smaller, or ''rat'' if it is larger. The common terms ''rat'' and ''mouse'' are not Taxonomy (biology), taxonomically specific. Typical mice are classified in the genus ''Mus (genus), Mus'', but the term ''mouse'' is not confined to members of ''Mus'' and can also apply to species from other genera such as the deer mouse, deer mouse (''Peromyscus''). Fancy mouse, Domestic mice sold as pets often differ substantially in size f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PEST Sequence
A PEST sequence is a peptide sequence that is rich in proline (P), glutamic acid (E), serine (S) and threonine (T). It is associated with proteins that have a short intracellular half-life, so might act as a signal peptide for protein degradation. This may be mediated via the proteasome or calpain A calpain (; , ) is a protein belonging to the family of calcium-dependent, non-lysosomal cysteine proteases ( proteolytic enzymes) expressed ubiquitously in mammals and many other organisms. Calpains constitute the C2 family of protease clan C .... References Peptide sequences Proteins Post-translational modification {{molecular-cell-biology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coiled Coil
A coiled coil is a structural motif in proteins in which two to seven alpha-helices are coiled together like the strands of a rope. ( Dimers and trimers are the most common types.) They have been found in roughly 5-10% of proteins and have a variety of functions. They are one of the most widespread motifs found in protein-protein interactions. To aid protein study, several tools have been developed to predict coiled-coils in protein structures. Many coiled coil-type proteins are involved in important biological functions, such as the regulation of gene expression — e.g., transcription factors. Notable examples are the oncoproteins c-Fos and c-Jun, as well as the muscle protein tropomyosin. Discovery The possibility of coiled coils for α-keratin was initially somewhat controversial. Linus Pauling and Francis Crick independently came to the conclusion that this was possible at about the same time. In the summer of 1952, Pauling visited the laboratory in England where C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isoelectric Point
The isoelectric point (pI, pH(I), IEP), is the pH at which a molecule carries no net electric charge, electrical charge or is electrically neutral in the statistical mean. The standard nomenclature to represent the isoelectric point is pH(I). However, pI is also used. For concision, brevity, this article uses pI. The net charge on the molecule is affected by pH of its surrounding environment and can become more positively or negatively charged due to the gain or loss, respectively, of protons#In Physics and biochemistry, protons (H+). Surfaces naturally charge to form a double layer (interfacial), double layer. In the common case when the surface charge-determining ions are H+/HO−, the net surface charge is affected by the pH of the liquid in which the solid is submerged. The pI value can affect the solubility of a molecule at a given pH. Such molecules have minimum solubility in water or salt solutions at the pH that corresponds to their pI and often precipitate out of Solutio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ciona Intestinalis
''Ciona intestinalis'' (sometimes known by the common name of vase tunicate) is an ascidian (sea squirt), a tunicate with very soft tunic. Its Latin name literally means "pillar of intestines", referring to the fact that its body is a soft, translucent column-like structure, resembling a mass of intestines sprouting from a rock. It is a globally distributed cosmopolitan species. Since Linnaeus described the species, ''Ciona intestinalis'' has been used as a model invertebrate chordate in developmental biology and genomics. Studies conducted between 2005 and 2010 have shown that there are at least two, possibly four, sister species. More recently it has been shown that one of these species has already been described as '' Ciona robusta''. By anthropogenic means, the species has invaded various parts of the world and is known as an invasive species. Although Linnaeus first categorised this species as a kind of mollusk, Alexander Kovalevsky found a tadpole-like larval stage durin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gallus Gallus
The red junglefowl (''Gallus gallus''), also known as the Indian red junglefowl (and formerly the bankiva or bankiva-fowl), is a species of Tropics, tropical, predominantly Terrestrial animal, terrestrial bird in the fowl and pheasant family, Phasianidae, found across much of Southeast Asia, Southeast and parts of South Asia. The red junglefowl was the primary species to give rise to today's many breeds of domesticated chicken (''G. g. domesticus''); additionally, the related grey junglefowl (''G. sonneratii''), Sri Lankan junglefowl (''G. lafayettii'') and the green junglefowl, Javanese green junglefowl (''G. varius'') have also contributed genetic material to the gene pool of the modern chicken. Molecular evidence, derived from Whole genome sequencing, whole-genome sequencing, has revealed that the chicken was first domestication, domesticated from red junglefowl ca. 8,000 years ago, with this domestication-event involving multiple maternal origins. Since then, the domestic fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pseudopodoces Humilis
The ground tit, Tibetan ground-tit or Hume's ground-tit (''Pseudopodoces humilis'') is a bird of the Tibetan plateau north of the Himalayas. The peculiar appearance confused ornithologists in the past who called it as Hume's groundpecker and still later as Hume's ground jay or Tibetan ground jay assuming it belonged to the family Corvidae that includes the crows and jays. Although morphologically confusing, the species has since been identified using molecular sequence comparisons as being a member of the tit family (Paridae) and is the only species in the genus ''Pseudopodoces''.James ''et al.'' (2003), del Hoyo ''et al.'' (2007) It is found in the Tibetan Plateau of China, India, Nepal & Bhutan. Description ''Pseudopodoces'' is somewhat similar in appearance to the unrelated ground jays (''Podoces''), but much smaller – about the size of a house sparrow (''Passer domesticus'') – and lacks any conspicuous markings. More distinctly however, it resembles a wheatear ('' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chrysemys Picta Bellii
The painted turtle (''Chrysemys picta'') is the most widespread native turtle of North America. It lives in relatively slow-moving fresh waters, from southern Canada to northern Mexico, and from the Atlantic to the Pacific. They have been shown to prefer large wetlands with long periods of inundation and emergent vegetation. This species is one of the few that is specially adapted to tolerate freezing temperatures for extended periods of time due to an antifreeze-like substance in their blood that keeps their cells from freezing. This turtle is a member of the genus ''Chrysemys'', which is part of the pond turtle family Emydidae. Fossils show that the painted turtle existed 15 million years ago. Three regionally based subspecies (the eastern, midland, and western) evolved during the Last glacial period, last ice age. The southern painted turtle (''C. dorsalis'') is alternately considered the only other species in ''Chrysemys'', or another subspecies of ''C. picta'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
