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Clinic For Special Children
The Clinic for Special Children (CSC) is a primary pediatric and adult care and genetic research clinic located in Gordonville, Pennsylvania. The facility specializes in genetic problems of the plain sects, such as the Amish and Old Order Mennonites. It was founded in 1989. The most common genetic disorders treated by the Clinic are glutaric acidemia type I (GA1), which is common in the Amish population and maple syrup urine disease (MSUD), which has a high prevalence in the Old Order Mennonites. Establishment The Clinic for Special Children was founded by the Plain community with Dr. D. Holmes Morton and his wife, Caroline in 1989. The original clinic building was raised by the Plain community in Strasburg, Pennsylvania and completed in 1990. In 2024, the organization moved to a new facility in Gordonville, Pennsylvania after a successful $13.3 million capital campaign. In addition to patient care facilities, the Clinic also houses its own laboratory, providing rapid bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health Care
Health care, or healthcare, is the improvement or maintenance of health via the preventive healthcare, prevention, diagnosis, therapy, treatment, wikt:amelioration, amelioration or cure of disease, illness, injury, and other disability, physical and mental impairments in people. Health care is delivered by health professionals and allied health professions, allied health fields. Medicine, dentistry, pharmacy, midwifery, nursing, optometry, audiology, psychology, occupational therapy, physical therapy, athletic training, and other health professions all constitute health care. The term includes work done in providing primary care, wikt:secondary care, secondary care, tertiary care, and public health. Access to health care may vary across countries, communities, and individuals, influenced by social and economic conditions and health policy, health policies. Providing health care services means "the timely use of personal health services to achieve the best possible health outcom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Washington Post
''The Washington Post'', locally known as ''The'' ''Post'' and, informally, ''WaPo'' or ''WP'', is an American daily newspaper published in Washington, D.C., the national capital. It is the most widely circulated newspaper in the Washington metropolitan area and has a national audience. As of 2023, the ''Post'' had 130,000 print subscribers and 2.5 million digital subscribers, both of which were the List of newspapers in the United States, third-largest among U.S. newspapers after ''The New York Times'' and ''The Wall Street Journal''. The ''Post'' was founded in 1877. In its early years, it went through several owners and struggled both financially and editorially. In 1933, financier Eugene Meyer (financier), Eugene Meyer purchased it out of bankruptcy and revived its health and reputation; this work was continued by his successors Katharine Graham, Katharine and Phil Graham, Meyer's daughter and son-in-law, respectively, who bought out several rival publications. The ''Post ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Genetics
Molecular genetics is a branch of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the structure and/or function of genes in an organism's genome using genetic screens. The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, cellular biology, molecular biology, biochemistry, and biotechnology. It integrates these disciplines to explore things like genetic inheritance, gene regulation and expression, and the molecular mechanism behind various life processes. A key goal of molecular genetics is to identify and study genetic mutations. Researchers search for mutations in a gene or induce mutations in a gene to link a gene sequence to a specific phenotype. Therefore molecular genetics is a powerful methodology for linking mutations to genetic conditions that may aid th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemical Genetics
Molecular biology is a branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observations of so-called classical biology, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strasburg, Pennsylvania
Strasburg is a borough in Lancaster County, Pennsylvania, United States. It developed as a linear village stretching approximately along the Great Conestoga Road, later known as the Strasburg Road.Susan M. Zacher, NRHP Nomination Form Strasburg/ref> The population was 3,117 at the 2020 census. The town was named after the then German city of Strasbourg, (today part of France) the native home of an early settler. The town is often called "Train Town USA" because of the many railroad attractions in and around town, including the Strasburg Rail Road and the Railroad Museum of Pennsylvania. Much of the movie ''Witness'' was filmed on a farm nearby. Much of the borough was listed as a historic district by the National Register of Historic Places in 1983. History The Old Conestoga Road was in use by 1714, and by 1750 a tavern and some log houses were built near the current site of Strasburg. The community grew as regional trade with Philadelphia grew. By 1759, there were 3 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barn Raising
A barn raising, also historically called a raising bee or rearing in the U.K., is an action in which a barn for a resident of a community is built or rebuilt collectively by its members. Barn raising was particularly common in 18th- and 19th-century rural North America. A barn was a necessary structure for any farmer, for example for storage of cereals and hay and keeping of animals. Yet a barn was also a large and costly structure, the assembly of which required more labor than a typical family could provide. Barn raising addressed the need by enlisting members of the community, unpaid, to assist in the building of their neighbors' barns. Because each member could ask others for help, reciprocation could eventually reasonably be presumed for each participant if the need were to arise. The tradition of "barn raising" continues, more or less unchanged, in some Amish and Old Order Mennonite communities, particularly in Ohio, Indiana, Pennsylvania, and some rural parts of Canada. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maple Syrup Urine Disease
Maple syrup urine disease (MSUD) is a rare, inherited metabolic disorder that affects the body's ability to metabolize amino acids due to a deficiency in the activity of the branched-chain alpha-ketoacid dehydrogenase (BCKAD) complex. It particularly affects the metabolism of amino acids leucine, isoleucine, and valine. With MSUD, the body is not able to properly break down these amino acids, therefore leading to the amino acids to build up in urine and become toxic. The condition gets its name from the distinctive sweet odor of affected infants' urine and earwax due to the buildup of these amino acids. Classification Maple syrup urine disease can be classified by its pattern of signs and symptoms or by its genetic cause. The most common and severe form of this disease is the classic type, which appears soon after birth, and as long as it remains untreated, gives rise to progressive and unremitting symptoms. Variant forms of the disorder may become apparent only later in infa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gordonville, Pennsylvania
Gordonville is an unincorporated community and census-designated place (CDP) in Leacock Township, Lancaster County, Pennsylvania, United States. The population was 508 as of the 2010 census. Though the village is little known outside its immediate area, the surrounding countryside has been portrayed in many books and magazine articles. The Old Order Amish constitute a significant cultural presence in the area of the village. Wendell Berry mentioned the town in one of his collections of essays. Geography The village is in eastern Lancaster County in the southwestern corner of Leacock Township, approximately east of the county seat of Lancaster, southwest of the village of Intercourse, less than one mile (1.1 km) north of Paradise, and about southeast of Bird-in-Hand. Gordonville is bordered to the southwest and south by Soudersburg. According to the U.S. Census Bureau, the Gordonville CDP has an area of , all land. The community drains south to Pequea Creek, a so ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Old Order Mennonites
Old Order Mennonites ( Pennsylvania German: ) form a branch of the Mennonite tradition. Old Order are those Mennonite groups of Swiss German and south German heritage who practice a lifestyle without some elements of modern technology, still drive a horse and buggy rather than cars, wear very conservative and modest dress, and have retained the old forms of worship, baptism and communion. All Old Order Mennonites reject certain technologies (e.g., radio, television, Internet), but the extent of this rejection depends on the individual group. Old Order groups generally place great emphasis on a disciplined community instead of the individual's personal faith beliefs. The Pennsylvania German language is spoken vigorously among all horse-and-buggy groups except the Virginia Old Order Mennonites, who lost their original language before becoming Old Order. There is no overall church or conference to unite all the different groups of Old Order Mennonites. In 2008–2009, a minorit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amish
The Amish (, also or ; ; ), formally the Old Order Amish, are a group of traditionalist Anabaptism, Anabaptist Christianity, Christian Christian denomination, church fellowships with Swiss people, Swiss and Alsace, Alsatian origins. As they maintain Nonconformity to the world#Anabaptism, a degree of separation from surrounding populations, and hold their faith in common, the Amish have been described by certain scholars as an ethnoreligious group, combining features of an ethnicity and a Christian denomination. The Amish are closely related to Old Order Mennonites and Conservative Mennonites, denominations that are also a part of Anabaptist Christianity. The Amish are known for simple living, plain dress, Christian pacifism#Anabaptist churches, Christian pacifism, and slowness to adopt many conveniences of modern technology, with a view neither to interrupt family time, nor replace face-to-face conversations whenever possible, and a view to maintain self-sufficiency. The Amis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
