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Centrocone
Centrocones are sub-cellular structures involved in the cell division of apicomplexan parasites. Centrocones are a nuclear sub-compartment in parasites of Toxoplasma gondii that work in apposition with the centrosome In cell biology, the centrosome (Latin centrum 'center' + Greek sōma 'body') (archaically cytocentre) is an organelle that serves as the main microtubule organizing center (MTOC) of the animal cell, as well as a regulator of cell-cycle progre ... to coordinate the budding process in mitosis. The centrocone concentrates and organizes various regulatory factors involved in the early stages of mitosis, including the ECR1 and TgCrk5 proteins. The membrane occupation and recognition nexus 1 ( MORN1) protein is also contained in this structure and is linked to human diseases, though not much is yet known about the connection between the centrocone and the MORN1 protein. Centrocones are located in the nuclear envelope and contain spindles that are used in mitosis. Chromo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apicomplexan
The Apicomplexa (also called Apicomplexia; single: apicomplexan) are organisms of a large phylum of mainly parasitic alveolates. Most possess a unique form of organelle structure that comprises a type of non-photosynthetic plastid called an apicoplastwith an apical complex membrane. The organelle's apical shape is an adaptation that the apicomplexan applies in penetrating a host cell. The Apicomplexa are unicellular and spore-forming. Most are obligate endoparasites of animals, except ''Nephromyces'', a symbiont in marine animals, originally classified as a chytrid fungus, and the Chromerida, some of which are photosynthetic partners of corals. Motile structures such as flagella or pseudopods are present only in certain gamete stages. The Apicomplexa are a diverse group that includes organisms such as the coccidia, gregarines, piroplasms, haemogregarines, and plasmodia. Diseases caused by Apicomplexa include: * Babesiosis (''Babesia'') * Malaria (''Plasmodium'') * Cryptospori ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Division
Cell division is the process by which a parent cell (biology), cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which the cell grows and replicates its chromosome(s) before dividing. In eukaryotes, there are two distinct types of cell division: a vegetative division (mitosis), producing daughter cells genetically identical to the parent cell, and a cell division that produces Haploidisation, haploid gametes for sexual reproduction (meiosis), reducing the number of chromosomes from two of each type in the diploid parent cell to one of each type in the daughter cells. Mitosis is a part of the cell cycle, in which, replicated chromosomes are separated into two new Cell nucleus, nuclei. Cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. In general, mitosis (division of the nucleus) is preceded by the S stage of interphase (during which the DNA replication occurs) and is f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxoplasma Gondii
''Toxoplasma gondii'' () is a species of parasitic alveolate that causes toxoplasmosis. Found worldwide, ''T. gondii'' is capable of infecting virtually all warm-blooded animals, but members of the cat family (felidae) are the only known definitive host#Hosts to parasites, definitive hosts in which the parasite may undergo sexual reproduction. In rodents, ''T. gondii'' Behavior-altering parasites and parasitoids, alters behavior in ways that increase the rodents' chances of being Predation, preyed upon by felids. Support for this "manipulation hypothesis" stems from studies showing that ''T. gondii''-infected rats have a decreased aversion to cat urine while infection in mice lowers general anxiety, increases explorative behaviors and increases a loss of aversion to predators in general. Because cats are one of the only hosts within which ''T. gondii'' can sexually reproduce, such behavioral manipulations are thought to be Adaptation, evolutionary adaptation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centrosome
In cell biology, the centrosome (Latin centrum 'center' + Greek sōma 'body') (archaically cytocentre) is an organelle that serves as the main microtubule organizing center (MTOC) of the animal cell, as well as a regulator of cell-cycle progression. The centrosome provides structure for the cell. It is thought to have evolved only in the metazoan lineage of eukaryotic cells. Fungi and plants lack centrosomes and therefore use other structures to organize their microtubules. Although the centrosome has a key role in efficient mitosis in animal cells, it is not essential in certain fly and flatworm species. Centrosomes are composed of two centrioles arranged at right angles to each other, and surrounded by a dense, highly structured mass of protein termed the pericentriolar material (PCM). The PCM contains proteins responsible for microtubule nucleation and anchoring — including γ-tubulin, pericentrin and ninein. In general, each centriole of the centrosome is based on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morn1
MORN1 containing repeat 1, also known as Morn1, is a protein that in humans is encoded by the ''MORN1'' gene. The function of Morn1 is not yet well understood. Orthologs have been found in eukaryotes and bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr .... Gene The MORN1 gene is located on chromosome 1 at locus 1p36.33 and contains 7 MORN repeats. It has 1641 base pairs in 14 exons in the reference sequence mRNA transcript. MORN1 is nearby the SKI gene which encodes the SKI protein, LOC100129534, and RER1 gene on the positive strand of chromosome 1. On the minus strand, the PEX10 gene occurs further upstream of Morn1. Alternative splicing MORN1 contains 19 different GT-AG introns, and 15 different mRNAs; 11 of which are produced by alternative splicing and 4 of whi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
