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CYB210010
CYB210010, also known as 2C-T-TFM or 2C-T-36 and as 2,5-dimethoxy-4-(trifluoromethylsulfanyl)phenethylamine, is a lesser-known psychedelic drug of the phenethylamine family related to compounds such as 2C-T and 2C-T-21. Alexander Shulgin attempted to synthesise this compound in the 1990s, and mentions it in his book PiHKAL under the entry for 2C-T-21, but was unsuccessful in producing a key intermediate and never assigned it a 2C-T number. This compound was ultimately first synthesised by Geoffrey Varty and colleagues at Irish biopharmaceutical company Cybin in 2023. It has a Ki of 0.35nM at the serotonin 5-HT2A receptor, and an of 4.1nM at the serotonin 5-HT2A receptor and 7.3nM at the serotonin 5-HT2C receptor, compared to 88nM at the serotonin 5-HT2B receptor. It is a potent, selective, long acting, and orally active agonist for the serotonin 5-HT2A and 5-HT2C receptors and produces psychedelic-like responding in several different animal species. The interaction ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C (psychedelics)
2C (2C-''x'') is a general name for the family of psychedelic drug, psychedelic substituted phenethylamine, phenethylamines containing Methoxy, methoxy groups on the 2 and 5 carbon, positions of a benzene ring. Most of these compounds also carry lipophilic substituents at the 4 position, usually resulting in more potent and more metabolism, metabolically stable and longer acting compounds. Most of the currently known 2C compounds were first synthesized by Alexander Shulgin in the 1970s and 1980s and published in his book ''PiHKAL'' (''Phenethylamines i Have Known And Loved''). Shulgin also coined the term 2C, being an acronym for the 2 carbon atoms between the benzene ring and the amino group. 2C-B is the most popular of the 2C drugs. Use The 2C drugs are oral administration, orally active, are used at oral doses of 6 to 150mg depending on the drug, and have duration of action, durations of 3 to 48hours depending on the drug. However, many have doses in the range of 10 to 60mg an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CYB005
CYB005, or CYB-005, also known as deuterated phenethylamine derivative, is a serotonin receptor agonist and serotonergic psychedelic which is under development for use at non-hallucinogenic doses in the treatment of psychiatric disorders and neuroinflammation. Pharmacology CYB005 acts as a serotonin receptor agonist and is a serotonergic psychedelic. In addition, CYB005 may also inhibit serotonin and dopamine Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. It is an amine synthesized ... reuptake. Chemistry It is a substituted phenethylamine, phenethylamine chemical derivative, derivative and a deuteration, deuterated chemical compound, compound. The exact chemical structure of CYB005 does not yet seem to have been disclosed. However, it appears to be closely related to CYB210010, which itself is non-deutera ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
