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Betaherpesvirinae
''Betaherpesvirinae'' is a subfamily of viruses in the order '' Herpesvirales'' and in the family ''Herpesviridae''. Mammals serve as natural hosts. There are 26 species in this subfamily, divided among 5 genera. Diseases associated with this subfamily include: human cytomegalovirus (HHV-5): congenital CMV infection; HHV-6: ' sixth disease' (also known as ''roseola infantum'' or ''exanthem subitum''); HHV-7: symptoms analogous to the 'sixth disease'. Genera ''Betaherpesvirinae'' consists of the following five genera: * ''Cytomegalovirus'' * '' Muromegalovirus'' * '' Proboscivirus'' * '' Quwivirus'' * '' Roseolovirus'' Structure Viruses in ''Betaherpesvirinae'' are enveloped, with icosahedral, spherical to pleomorphic, and Round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 140-240kb in length. Life cycle Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proboscivirus
''Proboscivirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Betaherpesvirinae''. Elephants serve as natural hosts. EEHV1 causes asymptomatic infection in African elephants but causes fatal haemorrhagic disease in Asian elephants. The name "''Proboscivirus''" comes from the Greek word or "proboscis" meaning "the elephant trunk," for which the virus accordingly uses as a means of contraction and transmission (secretions or openings of the trunk) to enter the elephant's body. Taxonomy ''Proboscivirus'' is located under the listings of the ICTV Updates as Section §2005.049-050V.04. With the creation of ''Proboscivirus'' as a new genus came the creation and categorization of a new species under this genus, by the name of ''Elephantid betaherpesvirus 1'' (Acronym: EEHV1 and Scientific Name: Elephant endotheliotropic herpesvirus Elephant endotheliotropic herpesviruses (EEHV) are herpesviruses that infect elephants. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytomegalovirus
''Cytomegalovirus'' (CMV) (from ''cyto-'' 'cell' via Greek - 'container' + 'big, megalo-' + -''virus'' via Latin 'poison') is a genus of viruses in the order '' Herpesvirales'', in the family '' Herpesviridae'', in the subfamily '' Betaherpesvirinae''. Humans and other primates serve as natural hosts. The 11 species in this genus include '' human betaherpesvirus 5'' (HCMV, human cytomegalovirus, HHV-5), which is the species that infects humans. Diseases associated with HHV-5 include mononucleosis and pneumonia, and congenital CMV in infants can lead to deafness and ambulatory problems. In the medical literature, most mentions of CMV without further specification refer implicitly to human CMV. Human CMV is the most studied of all cytomegaloviruses. MX2/MXB protein was identified as a restriction factor for herpesviruses, which acts at a very early stage of the replication cycle and MX2/MXB restriction of herpesvirus requires GTPase activity. Taxonomy Within the '' Her ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quwivirus
''Quwivirus'' is a genus of viruses in the subfamily ''Betaherpesvirinae'', in the family ''Herpesviridae'', in the order ''Herpesvirales ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans cause ....'' Species The genus consists of the following three species: * '' Quwivirus caviidbeta2'', also called Caviid betaherpesvirus 2 * '' Quwivirus miniopteridbeta1'', also called Miniopterid betaherpesvirus 1 * '' Quwivirus tupaiidbeta1'', also called Tupaiid betaherpesvirus 1 References Betaherpesvirinae Virus genera {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Cytomegalovirus
Human cytomegalovirus (HCMV), also called human herpesvirus 5 (HHV-5), is a species of virus in the genus ''Cytomegalovirus'', which in turn is a member of the viral family known as ''Herpesviridae'' or herpesviruses. It is also commonly called CMV. Within ''Herpesviridae'', HCMV belongs to the '' Betaherpesvirinae'' subfamily, which also includes cytomegaloviruses from other mammals. CMV is a double-stranded DNA virus. Although they may be found throughout the body, HCMV infections are frequently associated with the salivary glands. HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ transplant recipients, or newborn infants. Congenital cytomegalovirus infection can lead to significant morbidity and even death. After infection, HCMV remains latent within the body throughout life and can be reactivated at any time. Eventually, it may cause mucoepidermoid carcinoma and possibly o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Muromegalovirus
''Muromegalovirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Betaherpesvirinae''. Rodents serve as natural hosts. There are three species in this genus. Diseases associated with this genus include: infected peritoneal macrophages, dendritic cells (DC) and hepatocytes, inducing significant pathology in both the spleen and the liver. Murid viruses '' Murid betaherpesvirus 1'' (MuHV-1) and '' Murid betaherpesvirus 2'' (MuHV-2), previously defined as mouse cytomegalovirus ''Cytomegalovirus'' (CMV) (from ''cyto-'' 'cell' via Greek - 'container' + 'big, megalo-' + -''virus'' via Latin 'poison') is a genus of viruses in the order '' Herpesvirales'', in the family '' Herpesviridae'', in the subfamily '' Betaherp ... (MCMV) and rat cytomegalovirus (RCMV), belong to this genus. Species The following 3 species are assigned to the genus in ICTV 2022: * '' Muromegalovirus muridbeta1'' * '' Muromegalovirus muridbeta2'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roseolovirus
''Roseolovirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Betaherpesvirinae''. There are currently six species in this genus. Diseases associated with this genus include: HHV-6: sixth disease (roseola infantum, exanthema subitum); HHV-7: symptoms analog to the 'sixth disease'. Species The genus consists of the following six species: * '' Roseolovirus humanbeta7'' * '' Roseolovirus humanbeta6a'' * '' Roseolovirus humanbeta6b'' * '' Roseolovirus macacinebeta9'' * '' Roseolovirus muridbeta3'' * '' Roseolovirus suidbeta2'' Structure Viruses in ''Roseolovirus'' are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 200kb in length. Life cycle Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host recepto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Herpesvirus 7
Human herpesvirus 7 (HHV-7) is one of nine known members of the ''Herpesviridae'' family that infects humans. HHV-7 is a member of ''Betaherpesvirinae'', a subfamily of the ''Herpesviridae'' that also includes HHV-6 and ''Cytomegalovirus'' (HHV-5 or HCMV). HHV-7 often acts together with HHV-6, and the viruses together are sometimes referred to by their genus, '' Roseolovirus''. HHV-7 was first isolated in 1990 from CD4+ T cells taken from peripheral blood lymphocytes. Signs and symptoms Both HHV-6B and HHV-7, as well as other viruses, can cause a skin condition in infants known as exanthema subitum, although HHV-7 causes the disease less frequently than HHV-6B. HHV-7 infection also leads to or is associated with a number of other symptoms, including acute febrile respiratory disease, fever, rash, vomiting, diarrhea, low lymphocyte counts, and febrile seizures, though most often no symptoms present at all. There are indications that HHV-7 can contribute to the development ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Herpesvirus 6
Human herpesvirus 6 (HHV-6) is the common collective name for human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B). These closely related viruses are two of the nine known herpesviruses that have humans as their primary host. HHV-6A and HHV-6B are double-stranded DNA viruses within the ''Betaherpesvirinae'' subfamily and of the genus '' Roseolovirus''. HHV-6A and HHV-6B infect almost all of the human populations that have been tested. HHV-6A has been described as more neurovirulent, and as such is more frequently found in patients with neuroinflammatory diseases such as multiple sclerosis. HHV-6 (and HHV-7) levels in the brain are also elevated in people with Alzheimer's disease. HHV-6B primary infection is the cause of the common childhood illness exanthema subitum (also known as roseola infantum or sixth disease). It is passed on from child to child. It is uncommon for adults to contract this disease as most people have had it by kindergarten, and once contract ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Cytomegalovirus
Human cytomegalovirus (HCMV), also called human herpesvirus 5 (HHV-5), is a species of virus in the genus ''Cytomegalovirus'', which in turn is a member of the viral family known as ''Herpesviridae'' or herpesviruses. It is also commonly called CMV. Within ''Herpesviridae'', HCMV belongs to the '' Betaherpesvirinae'' subfamily, which also includes cytomegaloviruses from other mammals. CMV is a double-stranded DNA virus. Although they may be found throughout the body, HCMV infections are frequently associated with the salivary glands. HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ transplant recipients, or newborn infants. Congenital cytomegalovirus infection can lead to significant morbidity and even death. After infection, HCMV remains latent within the body throughout life and can be reactivated at any time. Eventually, it may cause mucoepidermoid carcinoma and possibly o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gammaherpesvirinae
''Gammaherpesvirinae'' is a subfamily of viruses in the order ''Herpesvirales'' and in the family ''Herpesviridae''. Viruses in ''Gammaherpesvirinae'' are distinguished by reproducing at a more variable rate than other subfamilies of ''Herpesviridae''. Mammals serve as natural hosts. Viruses associated with disease in this subfamily include Epstein–Barr virus and Kaposi's sarcoma-associated herpesvirus. Taxonomy Herpesviruses represent a group of double-stranded DNA viruses distributed widely within the animal kingdom. The family ''Herpesviridae'', which contains eight viruses that infect humans, is the most extensively studied group within this order and comprises three subfamilies, namely ''Alphaherpesvirinae'', ''Betaherpesvirinae'' and ''Gammaherpesvirinae''. Genera ''Gammaherpesvirinae'' consists of the following seven genera: * '' Bossavirus'' * '' Lymphocryptovirus'' * ''Macavirus'' * '' Manticavirus'' * '' Patagivirus'' * '' Percavirus'' * '' Rhadinovirus'' Str ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Herpesvirales
''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans caused by members of this order include cold sores, genital herpes, chickenpox, shingles, and glandular fever. ''Herpesvirales'' is the sole order in the class ''Herviviricetes'', which is the sole class in the phylum ''Peploviricota''. Virology Morphology All members of the order have a virion structure that consists of a DNA core surrounded by an icosahedral capsid composed of 12 pentavalent and 150 hexavalent capsomeres (T = 16). The capsid has a diameter of ~110 nanometers (nm) and is embedded in a proteinaceous matrix called the tegument, which in its turn is enclosed by a glycoprotein-containing lipid envelope with a diameter of about 200 nm. The DNA genome is linear and double stranded, with sizes in the range 125–290 kbp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
