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Brian David Dynlacht
Brian David Dynlacht (born September 3, 1965 in Brooklyn, New York), is an American biochemist and professor in the department of pathology of New York University Grossman School of Medicine at NYU Langone Health. Before moving his lab to New York University, he was an associate professor in the department of molecular and cellular biology at Harvard University. In 2002, while researching at the Harvard University, Dynlacht reported the discovery of CP110, which is now thought to be at the center of a molecular switch governing the centriole to ciliary transition in mammalian cells. His lab identified the first centriolar deubiquitinating enzyme, USP33, whose expression regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110, and thus regulates the centrosome duplication. Early life and education Brian David Dynlacht is the middle child of three children born to Sigmund (Zdzislaw) Dynlacht of Warsaw, Poland and Janice Deutsch of Brooklyn, New York. D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brooklyn, New York
Brooklyn () is a borough of New York City, coextensive with Kings County, in the U.S. state of New York. Kings County is the most populous county in the State of New York, and the second-most densely populated county in the United States, behind New York County (Manhattan). Brooklyn is also New York City's most populous borough,2010 Gazetteer for New York State United States Census Bureau. Retrieved September 18, 2016. with 2,736,074 residents in 2020. Named after the Dutch village of Breukelen, Brooklyn is located on the western portion of Long Island and shares a border with the borough of Queens. It has several bridge and tunnel connections to the borough of |
TFIID
Transcription factor II D (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells. It consists of RNA polymerase II, a subset of general transcription factors, and regulatory proteins known as SRB proteins. Before the start of transcription, the transcription Factor II D (TFIID) complex binds to the core promoter DNA of the gene through specific recognition of promoter sequence motifs, including the TATA box, Initiator, Downstream Promoter, Motif Ten, or Downstream Regulatory elements. Functions * Coordinates the activities of more than 70 polypeptides required for initiation of transcription by RNA polymerase II * Binds to the core promoter to position the polymerase properly * Serves as the scaffold for assembly of the remainder of the transcription complex * Acts as a chann ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Pathologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the " United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Biochemists
The 1st century was the century spanning AD 1 (Roman numerals, I) through AD 100 (Roman numerals, C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or History by period, historical period. The 1st century also saw the Christianity in the 1st century, appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius (AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and inst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American People Of Polish-Jewish Descent
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1965 Births
Events January–February * January 14 – The Prime Minister of Northern Ireland and the Taoiseach of the Republic of Ireland meet for the first time in 43 years. * January 20 ** Lyndon B. Johnson is Second inauguration of Lyndon B. Johnson, sworn in for a full term as President of the United States. ** Indonesian President Sukarno announces the withdrawal of the Indonesian government from the United Nations. * January 30 – The Death and state funeral of Winston Churchill, state funeral of Sir Winston Churchill takes place in London with the largest assembly of dignitaries in the world until the 2005 funeral of Pope John Paul II. * February 4 – Trofim Lysenko is removed from his post as director of the Institute of Genetics at the Russian Academy of Sciences, Academy of Sciences in the Soviet Union. Lysenkoism, Lysenkoist theories are now treated as pseudoscience. * February 12 ** The African and Malagasy Republic, Malagasy Common Organization ('; OCA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nathan H
Nathan or Natan may refer to: People *Nathan (given name), including a list of people and characters with this name *Nathan (surname) * Nathan (prophet), a person in the Hebrew Bible * Nathan (son of David), biblical figure, son of King David and Bathsheba *Nathan of Gaza, a charismatic figure who spread the word of Eli the Prophet * Starboy Nathan, a British singer who used the stage name "Nathan" from 2006 to 2011 *Nathan (footballer, born 1994), full name ''Nathan Athaydes Campos Ferreira'', Brazilian winger *Nathan (footballer, born 1995), full name ''Nathan Raphael Pelae Cardoso'', Brazilian centre back * Nathan (footballer, born 1996), full name ''Nathan Allan de Souza'', Brazilian midfielder *Nathan (footballer, born May 1999), full name ''Nathan Crepaldi da Cruz'', Brazilian forward * Nathan (footballer, born August 1999), full name ''Nathan Palafoz de Sousa'', Brazilian forward Other uses *Nathan, Queensland, a suburb of Brisbane in Australia *Nathan (band), an alt-c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Presidential Early Career Award For Scientists And Engineers
The Presidential Early Career Award for Scientists and Engineers (PECASE) is the highest honor bestowed by the United States government on outstanding scientists and engineers in the early stages of their independent research careers. The White House, following recommendations from participating agencies, confers the awards annually. To be eligible for a Presidential Award, an individual must be a US citizen, national or permanent resident. Some of the winning scientists and engineers receive up to a five-year research grant. History In February 1996, the National Science and Technology Council (NSTC), was commissioned by President Bill Clinton to create an award program that would honor and support the achievements of young professionals at the outset of their independent research careers in the fields of science and technology. The stated aim of the award is to help maintain the leadership position of the United States in science. Originally, 60 recipients received the PEC ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isaac Perlmutter
Isaac "Ike" Perlmutter ( he, יצחק "אייק" פרלמוטר; born December 1, 1942) is an Israeli-American billionairehttps://www.forbes.com/profile/isaac-perlmutter businessman and financier. He is the chairman and former CEO of Marvel Entertainment. He was also the owner of Remington Products and Marvel Toys. Early life Isaac Perlmutter was born to a Jewish family in then the British Mandate of Palestine (present-day Israel). He grew up in the State of Israel, serving in the Israeli military (IDF) during the Six-Day War of 1967. He emigrated to America, arriving in New York City with only $250, and he earned a living standing outside Jewish cemeteries in Brooklyn, leveraging his Hebrew skills to lead funeral services for tips. Spelling of wife's name -- Laurie -- at variance with other cites. Subscriber-check on name needed. Later he sold toys and beauty products on the streets of New York City, which eventually evolved into selling surplus stock and end-of-line items ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retinoblastoma Protein
The retinoblastoma protein (protein name abbreviated pRb; gene name abbreviated ''Rb'', ''RB'' or ''RB1'') is a proto-oncogenic tumor suppressor protein that is dysfunctional in several major cancers. One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. When the cell is ready to divide, pRb is phosphorylated, inactivating it, and the cell cycle is allowed to progress. It is also a recruiter of several chromatin remodeling enzymes such as methylases and acetylases. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomavirus, bind and inactivate pRb, this can lead to cancer. The ''RB'' gene may have been responsible for the evolution of multicellularity in several lineages of life including animals. Name and genetics In humans, the pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, '' in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
