Bordetella Hinzii
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Bordetella Hinzii
''Bordetella hinzii'' is a Gram-negative, oxidase+ and catalase-positive, short rod-shaped bacterium from the genus ''Bordetella'' isolated from a patient who suffered from cystic fibrosis and from the trachea and lungs of a laboratory mouse The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory animal sources for these mice are usually of the species ''Mus musculus''. They .... References External linksType strain of ''Bordetella hinzii'' at Bac''Dive'' - the Bacterial Diversity Metadatabase Burkholderiales Bacteria described in 1995 {{Betaproteobacteria-stub ...
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Gram-negative
Gram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. Their defining characteristic is that their cell envelope consists of a thin peptidoglycan cell wall sandwiched between an inner ( cytoplasmic) membrane and an outer membrane. These bacteria are found in all environments that support life on Earth. Within this category, notable species include the model organism '' Escherichia coli'', along with various pathogenic bacteria, such as '' Pseudomonas aeruginosa'', '' Chlamydia trachomatis'', and '' Yersinia pestis''. They pose significant challenges in the medical field due to their outer membrane, which acts as a protective barrier against numerous antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and the antimicrobial enzyme lysozyme produced by animals as part of their innate immune system. Furthe ...
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Oxidase
In biochemistry, an oxidase is an oxidoreductase (any enzyme that catalyzes a redox reaction) that uses dioxygen (O2) as the electron acceptor. In reactions involving donation of a hydrogen atom, oxygen is reduced to water (H2O) or hydrogen peroxide (H2O2). Some oxidation reactions, such as those involving monoamine oxidase or xanthine oxidase, typically do not involve free molecular oxygen. The oxidases are a subclass of the oxidoreductases. The use of dioxygen is the only unifying feature; in the EC classification, these enzymes are scattered in many categories. Examples An important example is EC 7.1.1.9 cytochrome c oxidase, the key enzyme that allows the body to employ oxygen in the generation of energy and the final component of the electron transfer chain. Other examples are: * EC 1.1.3.4 Glucose oxidase * EC 1.4.3.4 Monoamine oxidase * EC 1.14.-.- Cytochrome P450 oxidase * EC 1.6.3.1 NADPH oxidase * EC 1.17.3.2 Xanthine oxidase * EC 1.1.3.8 L-gulonolactone oxidase * EC 1. ...
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Catalase
Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals) which catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a very important enzyme in protecting the cell from oxidative damage by reactive oxygen species (ROS). Catalase has one of the highest turnover numbers of all enzymes; one catalase molecule can convert millions of hydrogen peroxide molecules to water and oxygen each second. Catalase is a tetramer of four polypeptide chains, each over 500 amino acids long. It contains four iron-containing heme groups that allow the enzyme to react with hydrogen peroxide. The optimum pH for human catalase is approximately 7, and has a fairly broad maximum: the rate of reaction does not change appreciably between pH 6.8 and 7.5. The pH optimum for other catalases varies between 4 and 11 depending on the species. The optimum temperature also varies by species. Structure Human catalase for ...
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Rod-shaped
Bacterial cellular morphologies are the shapes that are characteristic of various types of bacteria and often key to their identification. Their direct examination under a light microscope enables the classification of these bacteria (and archaea). Generally, the basic morphologies are spheres (coccus) and round-ended cylinders or rod shaped (bacillus). But, there are also other morphologies such as helically twisted cylinders (example '' Spirochetes''), cylinders curved in one plane (selenomonads) and unusual morphologies (the square, flat box-shaped cells of the Archaean genus '' Haloquadratum)''. Other arrangements include pairs, tetrads, clusters, chains and palisades. Types Coccus A coccus (plural ''cocci'', from the Latin ''coccinus'' (scarlet) and derived from the Greek ''kokkos'' (berry)), is any microorganism (usually bacteria) whose overall shape is spherical or nearly spherical. Coccus refers to the shape of the bacteria and can contain multiple genera, such as s ...
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Bacterium
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit the air, soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in mutualistic, commensal and ...
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Bordetella
''Bordetella'' () is a genus of small (0.2 – 0.7 μm), Gram-negative, coccobacilli bacteria of the phylum Pseudomonadota. ''Bordetella'' species, with the exception of ''Bordetella petrii, B. petrii'', are obligate aerobes, as well as highly Fastidious organism, fastidious, or difficult to culture. All species can infect humans. The first three species to be described (''Bordetella pertussis, B. pertussis'', ''Bordetella parapertussis, B. parapertussis'', ''Bordetella bronchiseptica, B. bronchiseptica'') are sometimes referred to as the 'classical species'. Two of these (''B. pertussis'' and ''B. bronchiseptica'') are also Motility, motile. There are about 16 different species of ''Bordetella'' likely descending from ancestors who lived in soil and/or water environments. ''B. pertussis'' and occasionally ''B. parapertussis'' cause pertussis (whooping cough) in humans, and some ''B. parapertussis'' strains only colonize sheep. It has also been known to cause bronchitis in c ...
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Cystic Fibrosis
Cystic fibrosis (CF) is a genetic disorder inherited in an autosomal recessive manner that impairs the normal clearance of Sputum, mucus from the lungs, which facilitates the colonization and infection of the lungs by bacteria, notably ''Staphylococcus aureus''. CF is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. The hallmark feature of CF is the accumulation of thick mucus in different organs. Long-term issues include Shortness of breath, difficulty breathing and coughing up mucus as a result of frequent pneumonia, lung infections. Other signs and symptoms may include Sinusitis, sinus infections, failure to thrive, poor growth, Steatorrhea, fatty stool, Nail clubbing, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies (alleles) ...
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Laboratory Mouse
The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory animal sources for these mice are usually of the species ''Mus musculus''. They are the most commonly used mammalian research model and are used for research in genetics, physiology, psychology, medicine and other scientific disciplines. Mice belong to the Euarchontoglires clade, which includes humans. This close relationship, the associated high homology with humans, their ease of maintenance and handling, and their high reproduction rate, make mice particularly suitable models for human-oriented research. The laboratory mouse genome has been sequenced and many mouse genes have human homologues. Lab mice are sold at pet stores for snake food and can also be kept as pets. Other mouse species sometimes used in laboratory research include two American species, the white-footed mouse (''Peromyscus leucopus'') and ...
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Journal Of Clinical Microbiology
The ''Journal of Clinical Microbiology'' is a monthly medical journal published by the American Society for Microbiology. The journal was established in 1975. The editor-in-chief is Alexander J. McAdam (Boston Children's Hospital). It is a delayed open access journal. Full text content is available free after a six-month embargo. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2023 impact factor of 6.1 See also * Clinical medicine * Clinical research Clinical research is a branch of medical research that involves people and aims to determine the effectiveness (efficacy) and safety of medications, devices, diagnostic products, and treatment regimens intended for improving human health. The ... * Medical microbiology References External links * {{Official website, http://jcm.asm.org/ American Society for Microbiology Delayed open access journals Microbiology journals Monthly journal ...
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Burkholderiales
The Burkholderiales are an order of ''Betaproteobacteria'' in the phylum ''Pseudomonadota''.George M. Garrity: '' Bergey's Manual of Systematic Bacteriology''. 2. Auflage. Springer, New York, 2005, Vol. 2: ''The Proteobacteria Part C: The Alpha-, Beta-, Delta-, and Epsilonproteabacteria'' Like all ''Pseudomonadota'', they are Gram-negative. They include several pathogenic bacteria, including species of '' Burkholderia'', ''Bordetella'', and '' Ralstonia''. They also include '' Oxalobacter'' and related genera, which are unusual in using oxalic acid Oxalic acid is an organic acid with the systematic name ethanedioic acid and chemical formula , also written as or or . It is the simplest dicarboxylic acid. It is a white crystalline solid that forms a colorless solution in water. Its name i ... as their source of carbon. Other well-studied genera include '' Alcaligenes'', ''Cupriavidus'', ''Achromobacter'', ''Comamonas'', ''Delftia'', ''Massilia (bacterium), Massilia'', ''Dugan ...
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