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Automated Pipetting System
An automated pipetting system is generally a device which performs programmed transfers of liquid between preselected groups of containers. The word ''"pipetting"'' is referring to the laboratory manual tool called pipette, which is commonly used in molecular biology, analytical chemistry, and medical tests, to transport a measured volume of liquid. Moreover, its performances are regulated by the International Standard International Organization for Standardization, ISO8655-1:2002. Automated pipetting systems are also commonly known as Liquid handling robot, Liquid Handling Robots; nevertheless the latter definition is preferred whenever add-on modules are present (e.g. Shaker (laboratory), laboratory shaker), while the former typically focuses on liquid transfer property. One of main advantages of these devices is the ability to enhance the reproducibility and the throughput of laboratory experiments. Components The vast majority of automated pipetting systems have the follow ...
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Automated Pipetting System Using Manual Pipettes
Automation describes a wide range of technologies that reduce human intervention in processes, namely by predetermining decision criteria, subprocess relationships, and related actions, as well as embodying those predeterminations in machines. Automation has been achieved by various means including mechanical, hydraulic, pneumatic, electrical, electronic devices, and computers, usually in combination. Complicated systems, such as modern factories, airplanes, and ships typically use combinations of all of these techniques. The benefit of automation includes labor savings, reducing waste, savings in electricity costs, savings in material costs, and improvements to quality, accuracy, and precision. Automation includes the use of various equipment and control systems such as machinery, processes in factories, boilers, and heat-treating ovens, switching on telephone networks, steering, and stabilization of ships, aircraft, and other applications and vehicles with reduced human ...
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Personal Computer
A personal computer (PC) is a multi-purpose microcomputer whose size, capabilities, and price make it feasible for individual use. Personal computers are intended to be operated directly by an end user, rather than by a computer expert or technician. Unlike large, costly minicomputers and mainframes, time-sharing by many people at the same time is not used with personal computers. Primarily in the late 1970s and 1980s, the term home computer was also used. Institutional or corporate computer owners in the 1960s had to write their own programs to do any useful work with the machines. While personal computer users may develop their own applications, usually these systems run commercial software, free-of-charge software (" freeware"), which is most often proprietary, or free and open-source software, which is provided in "ready-to-run", or binary, form. Software for personal computers is typically developed and distributed independently from the hardware or operating system ma ...
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Coefficient Of Variation
In probability theory and statistics, the coefficient of variation (CV), also known as relative standard deviation (RSD), is a standardized measure of dispersion of a probability distribution or frequency distribution. It is often expressed as a percentage, and is defined as the ratio of the standard deviation \sigma to the mean \mu (or its absolute value, The CV or RSD is widely used in analytical chemistry to express the precision and repeatability of an assay. It is also commonly used in fields such as engineering or physics when doing quality assurance studies and ANOVA gauge R&R, by economists and investors in economic models, and in neuroscience. Definition The coefficient of variation (CV) is defined as the ratio of the standard deviation \ \sigma to the mean \ \mu , c_ = \frac. It shows the extent of variability in relation to the mean of the population. The coefficient of variation should be computed only for data measured on scales that have a meaningfu ...
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Repeatability
Repeatability or test–retest reliability is the closeness of the agreement between the results of successive measurements of the same measure, when carried out under the same conditions of measurement. In other words, the measurements are taken by a single person or instrument on the same item, under the same conditions, and in a short period of time. A less-than-perfect test–retest reliability causes test–retest variability. Such variability can be caused by, for example, intra-individual variability and inter-observer variability. A measurement may be said to be ''repeatable'' when this variation is smaller than a pre-determined acceptance criterion. Test–retest variability is practically used, for example, in medical monitoring of conditions. In these situations, there is often a predetermined "critical difference", and for differences in monitored values that are smaller than this critical difference, the possibility of variability as a sole cause of the differen ...
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Accuracy
Accuracy and precision are two measures of '' observational error''. ''Accuracy'' is how close a given set of measurements (observations or readings) are to their '' true value'', while ''precision'' is how close the measurements are to each other. In other words, ''precision'' is a description of ''random errors'', a measure of statistical variability. ''Accuracy'' has two definitions: # More commonly, it is a description of only ''systematic errors'', a measure of statistical bias of a given measure of central tendency; low accuracy causes a difference between a result and a true value; ISO calls this ''trueness''. # Alternatively, ISO defines accuracy as describing a combination of both types of observational error (random and systematic), so high accuracy requires both high precision and high trueness. In the first, more common definition of "accuracy" above, the concept is independent of "precision", so a particular set of data can be said to be accurate, precise, both, ...
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Cross Contamination
Contamination is the presence of a constituent, impurity, or some other undesirable element that spoils, corrupts, infects, makes unfit, or makes inferior a material, physical body, natural environment, workplace, etc. Types of contamination Within the sciences, the word "contamination" can take on a variety of subtle differences in meaning, whether the contaminant is a solid or a liquid, as well as the variance of environment the contaminant is found to be in. A contaminant may even be more abstract, as in the case of an unwanted energy source that may interfere with a process. The following represent examples of different types of contamination based on these and other variances. Chemical contamination In chemistry, the term "contamination" usually describes a single constituent, but in specialized fields the term can also mean chemical mixtures, even up to the level of cellular materials. All chemicals contain some level of impurity. Contamination may be recognized or not an ...
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Polypropylene
Polypropylene (PP), also known as polypropene, is a thermoplastic polymer used in a wide variety of applications. It is produced via chain-growth polymerization from the monomer propylene. Polypropylene belongs to the group of polyolefins and is partially crystalline and non-polar. Its properties are similar to polyethylene, but it is slightly harder and more heat-resistant. It is a white, mechanically rugged material and has a high chemical resistance. Bio-PP is the bio-based counterpart of polypropylene (PP). Polypropylene is the second-most widely produced commodity plastic (after polyethylene). In 2019, the global market for polypropylene was worth $126.03 billion. Revenues are expected to exceed US$145 billion by 2019. The sales of this material are forecast to grow at a rate of 5.8% per year until 2021. History Phillips Petroleum chemists J. Paul Hogan and Robert Banks first demonstrated the polymerization of propylene in 1951. The stereoselective polymerization ...
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Plastic
Plastics are a wide range of synthetic or semi-synthetic materials that use polymers as a main ingredient. Their plasticity makes it possible for plastics to be moulded, extruded or pressed into solid objects of various shapes. This adaptability, plus a wide range of other properties, such as being lightweight, durable, flexible, and inexpensive to produce, has led to its widespread use. Plastics typically are made through human industrial systems. Most modern plastics are derived from fossil fuel-based chemicals like natural gas or petroleum; however, recent industrial methods use variants made from renewable materials, such as corn or cotton derivatives. 9.2 billion tonnes of plastic are estimated to have been made between 1950 and 2017. More than half this plastic has been produced since 2004. In 2020, 400 million tonnes of plastic were produced. If global trends on plastic demand continue, it is estimated that by 2050 annual global plastic production will reach over 1,1 ...
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Injection Molding
Injection moulding (U.S. spelling: injection molding) is a manufacturing process for producing parts by injecting molten material into a mould, or mold. Injection moulding can be performed with a host of materials mainly including metals (for which the process is called die-casting), glasses, elastomers, confections, and most commonly thermoplastic and thermosetting polymers. Material for the part is fed into a heated barrel, mixed (using a helical screw), and injected into a mould cavity, where it cools and hardens to the configuration of the cavity. After a product is designed, usually by an industrial designer or an engineer, moulds are made by a mould-maker (or toolmaker) from metal, usually either steel or aluminium, and precision-machined to form the features of the desired part. Injection moulding is widely used for manufacturing a variety of parts, from the smallest components to entire body panels of cars. Advances in 3D printing technology, using photopolymers th ...
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Air Displacement Pipette
Piston-driven air displacement pipettes are a type of micropipette, which are tools to handle volumes of liquid in the microliter scale. They are more commonly used in biology and biochemistry, and less commonly in chemistry; the equipment is susceptible to damage from many organic solvents. Operation These pipettes operate by piston-driven air displacement. A vacuum is generated by the vertical travel of a metallic or ceramic piston within an airtight sleeve. The upward movement of the piston, driven by the depression of the plunger, creates a vacuum in the space left vacant by the piston. To fill the vacuum, air from the tip rises, which is then replaced by the liquid that is drawn up into the tip and thus available for transport and dispensing elsewhere. Sterile technique prevents liquid from coming into contact with the pipette itself. Instead, the liquid is drawn into and dispensed from a disposable pipette tip that is discarded after transferring fluid and a new pipette ti ...
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Suction
Suction is the colloquial term to describe the air pressure differential between areas. Removing air from a space results in a pressure differential. Suction pressure is therefore limited by external air pressure. Even a perfect vacuum cannot suck with more pressure than is available in the surrounding environment. Suctions can form on the sea, for example, when a ship founders. When the pressure in one part of a physical system is reduced relative to another, the fluid in the higher pressure region will exert a force relative to the region of lowered pressure, referred to as pressure-gradient force. Pressure reduction may be static, as in a piston and cylinder arrangement, or dynamic, as in the case of a vacuum cleaner when air flow results in a reduced pressure region. When animals breathe, the diaphragm and muscles around the rib cage cause a change of volume in the lungs. The increased volume of the chest cavity decreases the pressure inside, creating an imbalance wit ...
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Gilson Pipette Tip
Gilson may refer to: Places *Gilson, Warwickshire, a hamlet in Warwickshire, England *Gilson, Illinois, a village in the United States *Gilson Butte in Utah, a United States rocket launching site Other uses *Gilson (name) *Gilson (footballer, born 1973), Macedonian football defensive midfielder *Gilson (footballer, born 1991), Santomean football defender *Gilson (basketball) (born 1956), Brazilian basketball players *Gilson, a common type of pipette * Gilson College, a Seventh-day Adventist School on the outskirts of Melbourne, Australia *Gilson Brothers Co. Gilson Brothers Co. was a Wisconsin-based manufacturer of outdoor power equipment and recreational equipment. It operated independently between its inception in 1911 until acquisition by Lawn-Boy in 1988. The company was probably most well known ...
, a manufacturer of outdoor power equipment {{disambiguation, geo, hndis ...
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