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Arbor Vitae (anatomy)
The arbor vitae (Latin for "tree of life") is the cerebellar white matter, so called for its branched, tree-like appearance. In some ways it more resembles a fern and is present in both cerebellar hemispheres. It brings sensory and motor information to and from the cerebellum. The arbor vitae is located deep in the cerebellum. Situated within the arbor vitae are the deep cerebellar nuclei; the dentate, globose, emboliform and the fastigial nuclei. These four different structures lead to the efferent projections of the cerebellum. Additional Images File:Arbor vitae by Sanjoy Sanyal.webm, Dissection video (1 min 14 s). Describing the arbor vitae. File:Midline sagittal view of the brainstem and cerebellum - Arbor vitae.png, Midsagittal section of the brainstem. File:Slide2qq.JPG, Midsagittal section of the brainstem. Arbor vitae labelled at the center. File:Sobo 1909 648.png, Midsagittal section of the brainstem. File:Sobo 1909 657.png, Coronal section of the cerebellum. File:16 ...
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Cerebellum
The cerebellum (: cerebella or cerebellums; Latin for 'little brain') is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as it or even larger. In humans, the cerebellum plays an important role in motor control and cognition, cognitive functions such as attention and language as well as emotion, emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to motor coordination, coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine motor skill, fine movement, sense of balance, equilibrium, list of human positions, posture, and motor learning in humans. ...
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Latin
Latin ( or ) is a classical language belonging to the Italic languages, Italic branch of the Indo-European languages. Latin was originally spoken by the Latins (Italic tribe), Latins in Latium (now known as Lazio), the lower Tiber area around Rome, Italy. Through the expansion of the Roman Republic, it became the dominant language in the Italian Peninsula and subsequently throughout the Roman Empire. It has greatly influenced many languages, Latin influence in English, including English, having contributed List of Latin words with English derivatives, many words to the English lexicon, particularly after the Christianity in Anglo-Saxon England, Christianization of the Anglo-Saxons and the Norman Conquest. Latin Root (linguistics), roots appear frequently in the technical vocabulary used by fields such as theology, List of Latin and Greek words commonly used in systematic names, the sciences, List of medical roots, suffixes and prefixes, medicine, and List of Latin legal terms ...
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Fastigial Nucleus
The fastigial nucleus (roof nucleus-1) is located in each cerebellar hemisphere. It is one of the four paired deep cerebellar nuclei of the cerebellum. It is made up of two sections: the rostral fastigial nucleus and the caudal fastigial nucleus. Anatomy The fastigial nuclei is situated atop the roof of the fourth ventricle (thence its name: "''fastigus''" is Latin for "summit"). The fastigial nucleus is a mass of gray matter nearest to the middle line at the anterior end of the superior vermis, immediately over the roof of the fourth ventricle (the peak of which is called the ''fastigium''), from which it is separated by a thin layer of white matter. It is smaller than the dentate nucleus, but somewhat larger than the emboliform nucleus and globose nucleus. Afferents The fastigial nucleus receives afferents from the vestibulocerebellar tract (containing first-order axons from the vestibular nerve as well as second-order axons from the vestibular nuclei), and fro ...
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Emboliform Nucleus
The emboliform nucleus is a deep cerebellar nucleus that lies immediately to the medial side of the dentate nucleus, partly covering its hilum. It is one of the four pairs of deep cerebellar nuclei, which are from lateral to medial: the dentate, emboliform, globose and fastigial. These nuclei can be seen using Weigert's elastic stain. In lower mammals the emboliform nucleus appears to be continuous with the globose nucleus, and these are known together as the interposed nucleus. ''Emboliform'', from Ancient Greek, means "shaped like a plug or wedge". Structure The emboliform nucleus is a wedge-shaped structure of gray matter found at the medial side of the hilum of the dentate nucleus. Its neurons display a similar structure from those of the dentate nucleus. In some mammals the emboliform nucleus is continuous with the globose nucleus, forming together the interposed nucleus. When present, the interposed nucleus can be divided in an anterior and a posterior inte ...
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Globose Nucleus
The globose nucleus is one of the deep cerebellar nuclei. It is located medial to the emboliform nucleus, and lateral to the fastigial nucleus. The ''globose nucleus'' and emboliform nucleus are known collectively as the interposed nuclei. The globose nucleus is part of a neural circuit giving rise to descending motor tracts involved in motor control of distal musculature of the upper and lower limbs. Anatomy Afferents * Purkinje cells of (the paravermal cortex of) the spinocerebellum * Anterior spinocerebellar tract (via restiform body of inferior cerebellar peduncle) Efferents * Contralateral (magnocellular division of) red nucleus (via the superior cerebellar peduncle). This is the major major efferent projection of the globose nucleus. The red nucleus in turn gives rise to the rubrospinal tract. * Ipsilateral ventral lateral nucleus of thalamus. The VL nucleus in turn projects to the primary motor cortex and premotor cortex (which then give rise to the lateral c ...
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Dentate Nucleus
The dentate nucleus refer to a pair of deep cerebellar nuclei deep within the white matter of the cerebellum of the brain with a dentate – tooth-like or serrated – edge. The dentate forms the largest pathway between the cerebellum and the remainder of the brain.Sultan, F., Hamodeh, S., & Baizer, J. S. (2010). THE HUMAN DENTATE NUCLEUS: A COMPLEX SHAPE UNTANGLED. rticle Neuroscience, 167(4), 965–968. It is the largest and most lateral of the four pairs of deep cerebellar nuclei, the others being the globose and emboliform nuclei, which together are referred to as the interposed nucleus, and the fastigial nucleus. The dentate nucleus is responsible for the planning, initiation and control of voluntary movements. The dorsal region of the dentate nucleus contains output channels involved in motor function, which is the movement of skeletal muscle, while the ventral region contains output channels involved in nonmotor function, such as conscious thought and visuospatial fun ...
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Deep Cerebellar Nuclei
There are four paired deep cerebellar nuclei embedded in the white matter centre of the cerebellum. The nuclei are the fastigial, globose, emboliform, and dentate nuclei. In lower mammals the emboliform nucleus appears to be continuous with the globose nucleus, and these are known together as the interposed nucleus. Inputs These nuclei receive inhibitory (GABAergic) inputs from Purkinje cells in the cerebellar cortex and excitatory (glutamatergic) inputs from mossy fiber and climbing fiber pathways. Most output fibers of the cerebellum originate from these nuclei. One exception is that fibers from the flocculonodular lobe synapse directly on vestibular nuclei without first passing through the deep cerebellar nuclei. The vestibular nuclei in the brainstem are analogous structures to the deep nuclei, since they receive both mossy fiber and Purkinje cell inputs. Eric Kandel (2021). Principles of Neural Science (6th ed.). McGraw-Hill. p. 909-929 Specific nuclei From lateral ...
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Cerebellar Hemisphere
The cerebellum consists of three parts, a median and two lateral, which are continuous with each other, and are substantially the same in structure. The median portion is constricted, and is called the vermis, from its annulated appearance which it owes to the transverse ridges and furrows upon it; the lateral expanded portions are named the hemispheres. Sections *The "intermediate hemisphere" is also known as the " spinocerebellum". *The "lateral hemisphere" is also known as the " pontocerebellum". *The lateral hemisphere is considered the portion of the cerebellum to develop most recently. Additional images File:Cerebellar hemisphere -- animation.gif, Animation. File:Cerebellar hemisphere --- animation.gif, Close up animation. File:Cerebellar hemisphere by Sanjoy Sanyal.webmsd.webm, Dissection video (45 s). Demonstrating the two cerebellar hemispheres. File:Human cerebellum anterior view description.JPG, Human cerebellum anterior view description (Cerebellar hemisphere is #8 ...
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White Matter
White matter refers to areas of the central nervous system that are mainly made up of myelinated axons, also called Nerve tract, tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials, acting as a relay and coordinating communication between different brain regions. White matter is named for its relatively light appearance resulting from the lipid content of myelin. Its white color in prepared specimens is due to its usual preservation in formaldehyde. It appears pinkish-white to the naked eye otherwise, because myelin is composed largely of lipid tissue veined with capillaries. Structure White matter White matter is composed of bundles, which connect various grey matter areas (the locations of nerve cell bodies) of the brain to each other, and carry nerve impulses between neurons. Myelin acts as an insulator, which allows saltatory conduction, electrical signals to jump, rather than cour ...
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Tree Of Life (biology)
The tree of life or universal tree of life is a metaphor, conceptual model, and research tool used to explore the evolution of life and describe the relationships between organisms, both living and extinct, as described in a famous passage in Charles Darwin's ''On the Origin of Species'' (1859). Tree diagrams originated in the Middle Ages, medieval era to represent family tree, genealogical relationships. Phylogenetic tree diagrams in the evolutionary sense date back to the mid-nineteenth century. The term phylogeny for the evolutionary relationships of species through time was coined by Ernst Haeckel, who went further than Charles Darwin, Darwin in proposing Phylogenetics, phylogenic histories of life. In contemporary usage, ''tree of life'' refers to the compilation of comprehensive phylogenetic databases rooted at the last universal common ancestor of life on Earth. Two public databases for the tree of life are ''TimeTree'', for phylogeny and divergence times, and the ''Ope ...
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Superior Colliculus
In neuroanatomy, the superior colliculus () is a structure lying on the tectum, roof of the mammalian midbrain. In non-mammalian vertebrates, the Homology (biology), homologous structure is known as the optic tectum or optic lobe. The adjective form ''tectum, tectal'' is commonly used for both structures. In mammals, the superior colliculus forms a major component of the midbrain. It is a paired structure and together with the paired inferior colliculi forms the corpora quadrigemina. The superior colliculus is a layered structure, with a pattern that is similar in all mammals. The layers can be grouped into the superficial layers (retinal nerve fiber layer, stratum opticum and above) and the deeper remaining layers. Neurons in the superficial layers receive direct input from the retina and respond almost exclusively to visual stimuli. Many neurons in the deeper layers also respond to other modalities, and some respond to stimuli in multiple modalities. The deeper layers also conta ...
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Midbrain
The midbrain or mesencephalon is the uppermost portion of the brainstem connecting the diencephalon and cerebrum with the pons. It consists of the cerebral peduncles, tegmentum, and tectum. It is functionally associated with vision, hearing, motor control, sleep and wakefulness, arousal (alertness), and temperature regulation.Breedlove, Watson, & Rosenzweig. Biological Psychology, 6th Edition, 2010, pp. 45-46 The name ''mesencephalon'' comes from the Greek ''mesos'', "middle", and ''enkephalos'', "brain". Structure The midbrain is the shortest segment of the brainstem, measuring less than 2cm in length. It is situated mostly in the posterior cranial fossa, with its superior part extending above the tentorial notch. The principal regions of the midbrain are the tectum, the cerebral aqueduct, tegmentum, and the cerebral peduncles. Rostral and caudal, Rostrally the midbrain adjoins the diencephalon (thalamus, hypothalamus, etc.), while Rostral and caudal, cau ...
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