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Fastigial Nucleus
The fastigial nucleus (roof nucleus-1) is located in each cerebellar hemisphere. It is one of the four paired deep cerebellar nuclei of the cerebellum. It is made up of two sections: the rostral fastigial nucleus and the caudal fastigial nucleus. Anatomy The fastigial nuclei is situated atop the roof of the fourth ventricle (thence its name: "''fastigus''" is Latin for "summit"). The fastigial nucleus is a mass of gray matter nearest to the middle line at the anterior end of the superior vermis, immediately over the roof of the fourth ventricle (the peak of which is called the ''fastigium''), from which it is separated by a thin layer of white matter. It is smaller than the dentate nucleus, but somewhat larger than the emboliform nucleus and globose nucleus. Afferents The fastigial nucleus receives afferents from the vestibulocerebellar tract (containing first-order axons from the vestibular nerve as well as second-order axons from the vestibular nuclei), and fro ...
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Cerebellum
The cerebellum (: cerebella or cerebellums; Latin for 'little brain') is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as it or even larger. In humans, the cerebellum plays an important role in motor control and cognition, cognitive functions such as attention and language as well as emotion, emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to motor coordination, coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine motor skill, fine movement, sense of balance, equilibrium, list of human positions, posture, and motor learning in humans. ...
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Vestibulocerebellum
The anatomy of the cerebellum can be viewed at three levels. At the level of gross anatomy, the cerebellum consists of a tightly folded and crumpled layer of cortex, with white matter underneath, several deep nuclei embedded in the white matter, and a fluid-filled ventricle in the middle. At the intermediate level, the cerebellum and its auxiliary structures can be broken down into several hundred or thousand independently functioning modules or compartments known as microzones. At the microscopic level, each module consists of the same small set of neuronal elements, laid out with a highly stereotyped geometry. Gross anatomy The human cerebellum is located at the base of the brain, with the large mass of the cerebrum above it, and the portion of the brainstem called the pons in front of it. It is separated from the overlying cerebrum by a layer of tough dura mater called the cerebellar tentorium; all of its connections with other parts of the brain travel through the pons. An ...
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Saccadic
In vision science, a saccade ( ; ; ) is a quick, simultaneous movement of both eyes between two or more phases of focal points in the same direction. In contrast, in smooth-pursuit movements, the eyes move smoothly instead of in jumps. Controlled cortically by the frontal eye fields (FEF), or subcortically by the superior colliculus, saccades serve as a mechanism for focal points, rapid eye movement, and the fast phase of optokinetic nystagmus. The word appears to have been coined in the 1880s by French ophthalmologist Émile Javal, who used a mirror on one side of a page to observe eye movement in silent reading, and found that it involves a succession of discontinuous individual movements. Function Humans and many organisms do not look at a scene in steadiness; instead, the eyes move around, locating interesting parts of the scene and building up a three-dimensional 'map' corresponding to the scene (as opposed to the graphical map of avians, which often relies upon detect ...
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Vestibular System
The vestibular system, in vertebrates, is a sensory system that creates the sense of balance and spatial orientation for the purpose of coordinating motor coordination, movement with balance. Together with the cochlea, a part of the auditory system, it constitutes the labyrinth of the inner ear in most Mammal, mammals. As movements consist of rotations and translations, the vestibular system comprises two components: the semicircular canals, which indicate Angular acceleration, rotational movements; and the otoliths, which indicate Acceleration, linear accelerations. The vestibular system sends signals primarily to the neural structures that control eye movement; these provide the anatomical basis of the vestibulo-ocular reflex, which is required for clear vision. Signals are also sent to the muscles that keep an animal upright and in general control Neutral spine, posture; these provide the anatomical means required to enable an animal to maintain its desired position in space. ...
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Reticulospinal
The reticular formation is a set of interconnected nuclei in the brainstem that spans from the lower end of the medulla oblongata to the upper end of the midbrain. The neurons of the reticular formation make up a complex set of neural networks in the core of the brainstem. The reticular formation is made up of a diffuse net-like formation of reticular nuclei which is not well-defined. It may be seen as being made up of all the interspersed cells in the brainstem between the more compact and named structures. The reticular formation is functionally divided into the ascending reticular activating system (ARAS), ascending pathways to the cerebral cortex, and the descending reticular system, descending pathways (reticulospinal tracts) to the spinal cord. Due to its extent along the brainstem it may be divided into different areas such as the midbrain reticular formation, the central mesencephalic reticular formation, the pontine reticular formation, the paramedian pontine reticular ...
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Vestibulospinal Tract
The vestibulospinal tract is a nerve tract in the central nervous system. Specifically, it is a component of the extrapyramidal system and is classified as a component of the medial pathway. Like other descending motor pathways, the vestibulospinal fibers of the tract relay information from nuclei to motor neurons. The vestibular nuclei receive information through the vestibulocochlear nerve about changes in the orientation of the head. The nuclei relay motor commands through the vestibulospinal tract. The function of these motor commands is to alter muscle tone, extend, and change the position of the limbs and head with the goal of supporting posture and maintaining balance of the body and head. Classification The vestibulospinal tract is part of the "extrapyramidal system" of the central nervous system. In human anatomy, the extrapyramidal system is a neural network located in the brain that is part of the motor system involved in the coordination of movement. The system is ...
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Inferior Cerebellar Peduncle
The inferior cerebellar peduncle is formed by fibers of the restiform body that join with fibers from the much smaller juxtarestiform body. The inferior cerebellar peduncle is the smallest of the three cerebellar peduncles. The upper part of the posterior district of the medulla oblongata is occupied by the inferior cerebellar peduncle, a thick rope-like strand situated between the lower part of the fourth ventricle and the roots of the glossopharyngeal and vagus nerves. Each cerebellar inferior peduncle connects the spinal cord and medulla oblongata with the cerebellum, and comprises the juxtarestiform body and restiform body. Important fibers running through the inferior cerebellar peduncle include the dorsal spinocerebellar tract and axons from the inferior olivary nucleus, among others. Function The inferior cerebellar peduncle carries many types of input and output fibers that are mainly concerned with integrating proprioceptive sensory input with motor vestibular ...
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Juxtarestiform Body
The juxtarestiform body is the smaller, medial subdivision of each inferior cerebellar peduncle (the other, lateral one being the restiform body). The juxtarestiform body contains mostly cerebellar afferents, but also some cerebellar efferents. Anatomy Afferents * Vestibulocerebellar fibers: include second-order fibers from the vestibular nuclei (project bilaterally) as well as a few first-order fibers from the vestibular ganglion/nerve (project ipsilaterally). The fibers project to the vestibulocerebellum and cerebellar vermis (of the spinocerebellum) as well as to (ipsilateral and contralateral) fastigial and dentate nuclei. Efferents * Cerebellovestibular fibers: arise from Purkinje cells of the flocculonodular lobe of the cerebellum. ** Fastigiovestibular fibers: mainly project to both ipsilateral and contralateral lateral and inferior vestibular nuclei to influence both vestibulospinal tracts. ** Fastigiobulbar fibers: project bilaterally to the (medullary and ...
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Ventral Lateral Nucleus
The ventral lateral nucleus (VL) is a nucleus in the ventral nuclear group of the thalamus. Inputs and outputs It receives neuronal inputs from the basal ganglia which includes the substantia nigra and the globus pallidus (via the thalamic fasciculus). It also has inputs from the cerebellum (via the dentatothalamic tract). It sends neuronal output to the primary motor cortex and premotor cortex. The ventral lateral nucleus in the thalamus forms the motor functional division in the thalamic nuclei along with the ventral anterior nucleus. The ventral lateral nucleus receives motor information from the cerebellum and the globus pallidus. Output from the ventral lateral nucleus then goes to the primary motor cortex. Functions The function of the ventral lateral nucleus is to target efferents including the motor cortex, premotor cortex, and supplementary motor cortex. Therefore, its function helps the coordination and planning of movement. It also plays a role in the learn ...
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Reticular Formation
The reticular formation is a set of interconnected nuclei in the brainstem that spans from the lower end of the medulla oblongata to the upper end of the midbrain. The neurons of the reticular formation make up a complex set of neural networks in the core of the brainstem. The reticular formation is made up of a diffuse net-like formation of reticular nuclei which is not well-defined. It may be seen as being made up of all the interspersed cells in the brainstem between the more compact and named structures. The reticular formation is functionally divided into the ascending reticular activating system (ARAS), ascending pathways to the cerebral cortex, and the descending reticular system, descending pathways ( reticulospinal tracts) to the spinal cord. Due to its extent along the brainstem it may be divided into different areas such as the midbrain reticular formation, the central mesencephalic reticular formation, the pontine reticular formation, the paramedian pontine reticul ...
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Purkinje Cell
Purkinje cells or Purkinje neurons, named for Czech physiologist Jan Evangelista Purkyně who identified them in 1837, are a unique type of prominent, large neuron located in the Cerebellum, cerebellar Cortex (anatomy), cortex of the brain. With their flask-shaped cell bodies, many branching Dendrite, dendrites, and a single long axon, these cells are essential for controlling motor activity. Purkinje cells mainly release GABA (gamma-aminobutyric acid) neurotransmitter, which inhibits some neurons to reduce nerve impulse transmission. Purkinje cells efficiently control and coordinate the body's motor motions through these inhibitory actions. Structure These Cell (biology), cells are some of the largest neurons in the human brain (Betz cells being the largest), with an intricately elaborate dendrite, dendritic arbor, characterized by a large number of dendritic spines. Purkinje cells are found within the Purkinje layer in the cerebellum. Purkinje cells are aligned like domi ...
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Cerebellar Hemisphere
The cerebellum consists of three parts, a median and two lateral, which are continuous with each other, and are substantially the same in structure. The median portion is constricted, and is called the vermis, from its annulated appearance which it owes to the transverse ridges and furrows upon it; the lateral expanded portions are named the hemispheres. Sections *The "intermediate hemisphere" is also known as the " spinocerebellum". *The "lateral hemisphere" is also known as the " pontocerebellum". *The lateral hemisphere is considered the portion of the cerebellum to develop most recently. Additional images File:Cerebellar hemisphere -- animation.gif, Animation. File:Cerebellar hemisphere --- animation.gif, Close up animation. File:Cerebellar hemisphere by Sanjoy Sanyal.webmsd.webm, Dissection video (45 s). Demonstrating the two cerebellar hemispheres. File:Human cerebellum anterior view description.JPG, Human cerebellum anterior view description (Cerebellar hemisphere is #8 ...
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