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André Sentenac
Georges André Sentenac (born 4 May 1939) is a French molecular biologist specializing in gene transcription. Married to Pierrette Balse, professor of mathematics at the University of Orsay, they had three children, all scientists, Anne, Marion and Daniel. Biography He was elected correspondent of the French Academy of sciences in 1999 and then a member of the Institute in 2007. Scientific career During his postdoctoral internship in Dr. George Acs' laboratory in New York City, Sentenac addresses the regulation of gene expression by showing that appropriate hormonal treatment forces a young male cockerel to produce certain specific components of the egg. Back in France, to bypass the complexity of higher organisms, he chose to work on the yeast Saccharomyces cerevisiae. In the following years, this yeast will become an essential study model in the molecular genetics of eukaryotic cells. First, he isolated and identified the essential components of the molecular machinery res ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Molecular Biology Organization
The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 2,100 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds courses, workshops and conferences, publishes five scientific journals and supports individual scientists. The organization was founded in 1964 and is a founding member of the Initiative for Science in Europe. the Director of EMBO is Fiona Watt, a stem cell researcher, professor at King's College London and a group leader at the European Molecular Biology Laboratory. __TOC__ Conferences and journals In recent years, EMBO has funded more than 80 meetings with more than 12,000 participants each year. EMBO publishes five peer-reviewed scientific journals: ''The EMBO Journal'', ''EMBO Reports'', '' Molecular Systems Biology'', '' EMBO Molecular Medicine'', and '' Life Science Alliance''. History The European Molecular Biology Organizatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Molecular Biologists
French may refer to: * Something of, from, or related to France ** French language, which originated in France ** French people, a nation and ethnic group ** French cuisine, cooking traditions and practices Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), a 2008 film * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a type of military jacket or tunic * French's, an American brand of mustard condiment * French (catheter scale), a unit of measurement * French Defence, a chess opening * French kiss, a type of kiss See also * France (other) * Franch, a surname * French Revolution (other) * French River (other), several rivers and other places * Frenching (other) * Justice French (other) Justice French may refer to: * C. G. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1939 Births
This year also marks the start of the World War II, Second World War, the largest and deadliest conflict in human history. Events Events related to World War II have a "WWII" prefix. January * January 1 ** Coming into effect in Nazi Germany of: *** The Protection of Young Persons Act (Germany), Protection of Young Persons Act, passed on April 30, 1938, the Working Hours Regulations. *** The small businesses obligation to maintain adequate accounting. *** The Jews name change decree. ** With his traditional call to the New Year in Nazi Germany, Führer and Reich Chancellor Adolf Hitler addresses the members of the National Socialist German Workers' Party (NSDAP). ** The Hewlett-Packard technology and scientific instruments manufacturing company is founded by Bill Hewlett and David Packard, in a garage in Palo Alto, California, considered the birthplace of Silicon Valley. ** Philipp Etter takes over as President of the Swiss Confederation. ** The Third Soviet Five Year P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legion Of Honour
The National Order of the Legion of Honour ( ), formerly the Imperial Order of the Legion of Honour (), is the highest and most prestigious French national order of merit, both military and Civil society, civil. Currently consisting of five classes, it was originally established in 1802 by Napoleon, Napoleon Bonaparte, and it has been retained (with occasional slight alterations) by all later French governments and regimes. The order's motto is ' ("Honour and Fatherland"); its Seat (legal entity), seat is the Palais de la Légion d'Honneur next to the Musée d'Orsay, on the left bank of the Seine in Paris. Since 1 February 2023, the Order's grand chancellor has been retired General François Lecointre, who succeeded fellow retired General Benoît Puga in office. The order is divided into five degrees of increasing distinction: ' (Knight), ' (Officer), ' (Commander (order), Commander), ' (Grand Officer) and ' (Grand Cross). History Consulate During the French Revolution, all ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ordre Des Palmes Académiques
A suite, in Western classical music, is an ordered set of instrumental or orchestral/concert band pieces. It originated in the late 14th century as a pairing of dance tunes; and grew in scope so that by the early 17th century it comprised up to five dances, sometimes with a prelude. The separate movements were often thematically and tonally linked. The term can also be used to refer to similar forms in other musical traditions, such as the Turkish fasıl and the Arab nuubaat. In the Baroque era, the suite was an important musical form, also known as ''Suite de danses'', ''Ordre'' (the term favored by François Couperin), ''Partita'', or ''Ouverture'' (after the theatrical "overture" which often included a series of dances) as with the orchestral suites of Christoph Graupner, Telemann and J.S. Bach. During the 18th century, the suite fell out of favour as a cyclical form, giving way to the symphony, sonata and concerto. It was revived in the later 19th century, but in a d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academia Europaea
The Academia Europaea is a pan-European Academy of humanities, letters, law, and sciences. The Academia was founded in 1988 as a functioning Europe-wide Academy that encompasses all fields of scholarly inquiry. It acts as co-ordinator of European interests in national research agencies. History The concept of a 'European Academy of Sciences' was raised at a meeting in Paris of the European Ministers of Science in 1985. The initiative was taken by the Royal Society (United Kingdom) which resulted in a meeting in London in June 1986 of Arnold Burgen (United Kingdom), Hubert Curien (France), Umberto Colombo (Italy), David Magnusson (Sweden), Eugen Seibold (Germany) and Ruurd van Lieshout (the Netherlands) – who agreed to the need for a new body. The meeting also included Brian Flowers and John Kendrew. Another, larger meeting took place in October 1986 with participants representing some countries in the Council of Europe and was in support for the development of a Eur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CNRS Silver Medal
The CNRS Silver Medal is a scientific award given every year to about fifteen researchers by the French National Centre for Scientific Research (CNRS). It is awarded to a researcher for "the originality, quality and importance of their work, recognised on a national and international level". It is part of the "CNRS Talents" medals, along with the CNRS Gold Medal, CNRS gold medal, which rewards a whole scientific career, the CNRS bronze medal, which rewards young researchers, the Innovation medal, which honours remarkable work in the technological, therapeutic, economic or societal fields, and the CNRS Crystal medal, which rewards research support staff. Notable recipients * Gabriel Peyré (mathematics) (2021) * Marie-Hélène Verlhac (biology) (2021) * Claire Mathieu (computer science) (2019) * Margaret Maruani (sociology) (2014) * Marie-Françoise André (2011) * Anca Muscholl (mathematics) (2010) * Edith Heard (biology) (2008) * Marc Fontecave (2004) * Leanne Pitchford (ph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
5S Ribosomal RNA
The 5S ribosomal RNA (5S rRNA) is an approximately 120 nucleotide-long ribosomal RNA molecule with a mass of 40 kDa. It is a structural and functional component of the large subunit of the ribosome in all domains of life (bacteria, archaea, and eukaryotes), with the exception of mitochondrial ribosomes of fungi and animals. The designation 5S refers to the molecule's sedimentation coefficient in an ultracentrifuge, which is measured in Svedberg units (S). Biosynthesis In prokaryotes, the 5S rRNA gene is typically located in the rRNA operons downstream of the small and the large subunit rRNA, and co-transcribed into a polycistronic precursor. A particularity of eukaryotic nuclear genomes is the occurrence of multiple 5S rRNA gene copies (5S rDNA) clustered in tandem repeats, with copy number varying from species to species. Eukaryotic 5S rRNA is synthesized by RNA polymerase III, whereas other eukaryotic rRNAs are cleaved from a 45S precursor transcribed by RNA polymerase ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription (biology)
Transcription is the process of copying a segment of DNA into RNA for the purpose of gene expression. Some segments of DNA are transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding RNAs (ncRNAs). Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a Complementarity (molecular biology), complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, Antiparallel (biochemistry), antiparallel RNA strand called a primary transcript. In virology, the term transcription is used when referring to mRNA synthesis from a viral RNA molecule. The genome of many Orthornavirae, RNA viruses is composed of Sense (molecular biology), negative-sense RNA which acts as a template for positive sense viral messenger RNA - a necessary step in the synthesis of viral proteins needed for viral replication. This process ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transfer RNA
Transfer ribonucleic acid (tRNA), formerly referred to as soluble ribonucleic acid (sRNA), is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in eukaryotes). In a cell, it provides the physical link between the genetic code in messenger RNA (mRNA) and the amino acid sequence of proteins, carrying the correct sequence of amino acids to be combined by the protein-synthesizing machinery, the ribosome. Each three-nucleotide codon in mRNA is complemented by a three-nucleotide anticodon in tRNA. As such, tRNAs are a necessary component of translation, the biological synthesis of new proteins in accordance with the genetic code. Overview The process of translation starts with the information stored in the nucleotide sequence of DNA. This is first transformed into mRNA, then tRNA specifies which three-nucleotide codon from the genetic code corresponds to which amino acid. Each mRNA codon is recognized by a particular type of tRNA, which docks to it along ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RNA Polymerase
In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that catalyzes the chemical reactions that synthesize RNA from a DNA template. Using the enzyme helicase, RNAP locally opens the double-stranded DNA so that one strand of the exposed nucleotides can be used as a template for the synthesis of RNA, a process called transcription. A transcription factor and its associated transcription mediator complex must be attached to a DNA binding site called a promoter region before RNAP can initiate the DNA unwinding at that position. RNAP not only initiates RNA transcription, it also guides the nucleotides into position, facilitates attachment and elongation, has intrinsic proofreading and replacement capabilities, and termination recognition capability. In eukaryotes, RNAP can build chains as long as 2.4 million nucleotides. RNAP produces RNA that, functionally, is either for protei ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
