4-HO-NALT
4-Hydroxy-''N''-allyltryptamine (4-HO-NALT) is a tryptamine derivative developed by modification of norpsilocin (4-HO-NMT). It produces a head-twitch response in mice consistent with psychedelic-like activity, as do the corresponding ethyl, propyl, isopropyl and benzyl derivatives (4-HO-NET, 4-HO-NPT, 4-HO-NiPT and 4-HO-NBnT), but the bulkier t-butyl and cyclohexyl derivatives are inactive. See also * 4-AcO-DALT * 4-HO-MALT * 5-HO-DiPT * 5-MeO-T-NBOMe * N-t-Butyltryptamine, NTBT References

Allylamines 4-Hydroxytryptamines N-Monoalkyltryptamines Psychedelic tryptamines Secondary amines {{psychoactive-stub ...
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Norpsilocin
Norpsilocin, also known as 4-hydroxy-''N''-methyltryptamine (4-HO-NMT), is a tryptamine alkaloid recently discovered in 2017 in the psychedelic mushroom ''Psilocybe cubensis''. It is hypothesized to be a dephosphorylated metabolite of baeocystin. Norpsilocin was found to be a near full agonist of the 5-HT2A receptor and was found to be more potent than psilocin. It also has affinity for other serotonin receptors. Moreover, it has been found to cross the blood–brain barrier in animals and to have good metabolic stability similarly to psilocin. Norpsilocin has shown psilocin-related peripheral effects in animals, including decreased spinal reflexes such as knee jerk response (opposite effect to psilocin), antiserotonergic activity (14% of that of psilocin), and pressor activity (70% of that of psilocin). Surprisingly however, in spite of its serotonin 5-HT2A receptor agonism and psilocin-like effects, norpsilocin failed to induce the head-twitch response, a behavioral proxy ...
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