3-chloropropanol
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3-chloropropanol
Chloropropanols are chlorohydrins related to propanols containing chloride functional group. Eight isomers are possible. Two of these derivatives, 1,3-dichloropropanol (1,3-DCP) and 3-chloropropane-1,2-diol (3-MCPD), are carcinogenic contaminants in processed foods. Several isomers are encountered in industrial chemistry. Monochloropropanols: * 2-Chloro-1-propanol * 3-Chloro-1-propanol * 1-Chloro-2-propanol Dichloropropanols: * 1,2-Dichloropropanol * 1,3-Dichloropropanol 1,3-Dichloropropan-2-ol (1,3-DCP) is an organic compound with the formula HOCH2CHClCH2Cl. It is a colorless liquid. It is an intermediate in the production of epichlorohydrin. 1,3-DCP is a believed to be a carcinogen and mutagen. The Internati ... (1,3-DCP) Chloropropanediols: * 3-Chloropropane-1,2-diol (3-MCPD) * 2-Chloropropane-1,3-diol {{chemistry index ...
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Chlorohydrin
In organic chemistry a halohydrin (also a haloalcohol or β-halo alcohol) is a functional group in which a halogen and a hydroxyl are bonded to adjacent carbon atoms, which otherwise bear only hydrogen or hydrocarbyl groups (e.g. 2-chloroethanol, 3-chloropropane-1,2-diol). The term only applies to saturated motifs, as such compounds like 2-chlorophenol would not normally be considered halohydrins. Megatons of some chlorohydrins, e.g. propylene chlorohydrin, are produced annually as precursors to polymers. Halohydrins may be categorized as chlorohydrins, bromohydrins, fluorohydrins or iodohydrins depending on the halogen present. Synthesis From alkenes Halohydrins are usually prepared by treatment of an alkene with a halogen, in the presence of water. The reaction is a form of electrophilic addition, with the halogen acting as electrophile. In that regard, it resembles the halogen addition reaction and proceeds with anti addition, leaving the newly added X and OH groups in ...
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Propanol
There are two isomers of propanol. * 1-Propanol, ''n''-propanol, or propan-1-ol: CH3CH2CH2OH, the most common meaning *2-Propanol, isopropyl alcohol, isopropanol, or propan-2-ol: (CH3)2CHOH See also * Propanal (propionaldehyde) differs in spelling from propanol by a single letter and is a different compound. * Propranolol Propranolol is a medication of the beta blocker class. It is used to treat hypertension, high blood pressure, some types of cardiac dysrhythmia, irregular heart rate, thyrotoxicosis, capillary hemangiomas, akathisia, performance anxiety, and ... is a drug used for reducing blood pressure and hand tremors. {{Authority control Alkanols ...
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1,3-dichloropropanol
1,3-Dichloropropan-2-ol (1,3-DCP) is an organic compound with the formula HOCH2CHClCH2Cl. It is a colorless liquid. It is an intermediate in the production of epichlorohydrin. 1,3-DCP is a believed to be a carcinogen and mutagen. The International Agency for Research on Cancer classifies it as a Group 2B carcinogen ("possibly carcinogenic to humans"). Along with 3-monochloropropane-1,2-diol (3-MCPD), 1,3-DCP is found in some Asian style sauces such as soy sauce and oyster sauce Oyster sauce describes a number of sauces made by cooking oysters. The most common in modern use is a viscous dark brown condiment made from oyster extracts,The Times, 22 January 1981; ''Cook Accidentally on purpose'' sugar, salt and water, thi .... References {{DEFAULTSORT:Dichloropropan-2-ol, 1, 3- Secondary alcohols Organochlorides IARC Group 2B carcinogens ...
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3-MCPD
3-MCPD (3-monochloropropane-1,2-diol or 3-chloropropane-1,2-diol) is an organic chemical compound with the formula HOCH2CH(OH)CH2Cl. It is a colorless liquid. The compound has attracted notoreity as the most common member of chemical food contaminants known as chloropropanols. It is suspected to be carcinogenic in humans. Accidental and intentional production 3-MCPD, together with its isomer 2-MCPD, is thought to be produced when fat-containing foods are treated at high temperatures with hydrochloric acid. Such treatments are sometimes used to accelerate protein hydrolysis, making food more digestable. In such a treatment chloride is thought to react with the glycerol backbone of lipids to produce 3-MCPD and 2-MCPD. Chlorination of glycerol gives the 3-MCPD: : The same compound can be produced by hydrolysis of epichlorohydrin. Occurrence In 2009, 3-MCPD was found in some East Asian and Southeast Asian sauces such as oyster sauce, Hoisin sauce, and soy sauce. Using h ...
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1,2-Dichloropropanol
Onekama ( ) is a village in Manistee County in the U.S. state of Michigan. The population was 399 at the 2020 census. The village is located on the northeast shore of Portage Lake and is surrounded by Onekama Township. The town's name is derived from ''Ona-ga-maa'', an Anishinaabe word which means "singing water". History The predecessor of the village of Onekama was the settlement of Portage at Portage Point, first established in 1845, at the western end of Portage Lake, at the outlet of Portage Creek. In 1871, when landowners around the land-locked lake became exasperated with the practices of the Portage Sawmill, they took the solution into their own hands and dug a channel through the narrow isthmus, opening a waterway that lowered the lake by and brought it to the same level as Lake Michigan. When this action dried out Portage Creek on May 14, 1871, the settlement, which had only the week before been designated as "Onekama" with a post office under that name, moved to th ...
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1,3-Dichloropropanol
1,3-Dichloropropan-2-ol (1,3-DCP) is an organic compound with the formula HOCH2CHClCH2Cl. It is a colorless liquid. It is an intermediate in the production of epichlorohydrin. 1,3-DCP is a believed to be a carcinogen and mutagen. The International Agency for Research on Cancer classifies it as a Group 2B carcinogen ("possibly carcinogenic to humans"). Along with 3-monochloropropane-1,2-diol (3-MCPD), 1,3-DCP is found in some Asian style sauces such as soy sauce and oyster sauce Oyster sauce describes a number of sauces made by cooking oysters. The most common in modern use is a viscous dark brown condiment made from oyster extracts,The Times, 22 January 1981; ''Cook Accidentally on purpose'' sugar, salt and water, thi .... References {{DEFAULTSORT:Dichloropropan-2-ol, 1, 3- Secondary alcohols Organochlorides IARC Group 2B carcinogens ...
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