Escaline (3,5-methoxy-4-ethoxyphenethylamine) is a
psychedelic drug and
entheogen
Entheogens are psychoactive substances that induce alterations in perception, mood, consciousness, cognition, or behavior for the purposes of engendering spiritual development or otherwiseRätsch, Christian, ''The Encyclopedia of Psychoac ...
of the
phenethylamine class of compounds. Escaline was first synthesized and reported in the scientific literature by Benington, et al., in 1954, but was later re-examined in the laboratory of
David E. Nichols, who prepared a series of
mescaline analogues that included escaline,
proscaline
Proscaline (4-propoxy-3,5-DMPEA) is a psychedelic and hallucinogenic drug. It has structural properties similar to the drugs mescaline, isoproscaline, and escaline. In '' PiHKAL'', Alexander Shulgin reports that a dose of 30–60 mg produ ...
, and
isoproscaline. The effects of this and related
mescaline analogues in humans were first described by
Alexander Shulgin. In his book ''
PiHKAL (Phenethylamines i Have Known And Loved)'', Shulgin lists the dosage range as 40 to 60 mg, consumed orally. The duration of action was stated to be 8–12 hours.
Escaline is the
phenethylamine analog of
3C-E and the 4-ethoxy analog of
mescaline.
Legal status
Escaline is illegal in Sweden as of 26 January 2016.
Escaline is a Schedule I controlled substance (DEA #7930) in the United States as it is a positional isomer of TMA (3,4,5-trimethoxyamphetamine).
References
See also
*
Functional analog (chemistry) In chemistry and pharmacology, functional analogs are chemical compounds that have similar physical, chemical, biochemical, or pharmacological properties. Functional analogs are not necessarily structural analogs with a similar chemical structure. ...
Psychedelic phenethylamines
Designer drugs
Phenol ethers
Mescalines
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