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Zebrafish Information Network
The Zebrafish Information NetworkZFIN is an online biological database of information about the zebrafish (''Danio rerio''). The zebrafish is a widely used model organism for genetic, genomic, and developmental studies, and ZFIN provides an integrated interface for querying and displaying the large volume of data generated by this research. To facilitate use of the zebrafish as a model of human biology, ZFIN links these data to corresponding information about other model organisms (e.g., mouse) and to human disease databases. Abundant links to external sequence databases (e.g., GenBank) and to genome browsers are included. Gene product, gene expression, and phenotype data are annotated with terms from biomedical ontologies. ZFIN is based at the University of Oregon in the United States, with funding provided by the National Institutes of Health (NIH). Contents ZFIN consists of two principal parts: # a website of community news and announcements, as well as biological resources such ...
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National Institutes Of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Services (HHS). Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its scientific research through the NIH Intramural Research Program (IRP) and provides significant biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical ...
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Xenbase
Xenbase is a Model Organism Database (MOD), providing informatics resources, as well as genomic and biological data on Xenopus frogs.M. Fisher et al. (2023Xenbase: key features and resources of the Xenopus model organism knowledgebase Genetics, Volume 224, Issue 1, May 2023, iyad018, Xenbase has been available since 1999, and covers both X. laevis and X. tropicalis Xenopus varieties. As of 2013 all of its services are running on virtual machines in a private cloud environment, making it one of the first MODs to do so.K. Karimi and P.D. Vize (2014)The Virtual Xenbase: transitioning an online bioinformatics resource to a private cloud Database, doi: 10.1093/database/bau108 Other than hosting genomics data and tools, Xenbase supports the Xenopus research community though profiles for researchers and laboratories, and job and events postings. Xenbase's Software and Hardware Platform Xenbase runs in a cloud environment. Its virtual machines are running in a VMware vSphere environm ...
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Flybase
FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae. For the most extensively studied species and model organism, ''Drosophila melanogaster'', a wide range of data are presented in different formats. Information in FlyBase originates from a variety of sources ranging from large-scale genome projects to the primary research literature. These data types include mutant phenotypes; molecular characterization of mutant alleles; and other deviations, cytological maps, wild-type expression patterns, anatomical images, transgenic constructs and insertions, sequence-level gene models, and molecular classification of gene product functions. Query tools allow navigation of FlyBase through DNA or protein sequence, by gene or mutant name, or through terms from the several ontologies used to capture functional, phenotypic, and anatomical data. The database offers several different query tools in order to provid ...
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Wormbase
WormBase is an online biological database about the biology and genome of the nematode model organism ''Caenorhabditis elegans'' and contains information about other related nematodes. WormBase is used by the ''C. elegans'' research community both as an information resource and as a place to publish and distribute their results. The database is regularly updated with new versions being released every two months. WormBase is one of the organizations participating in the Generic Model Organism Database (GMOD) project. It is also part of the Alliance of Genome Resources. Contents WormBase comprises the following main data sets: *The annotated genomes of ''Caenorhabditis elegans'', ''Caenorhabditis briggsae'', ''Caenorhabditis remanei'', ''Caenorhabditis brenneri'', ''Caenorhabditis angaria'', ''Pristionchus pacificus'', ''Haemonchus contortus'', ''Meloidogyne hapla'', ''Meloidogyne incognita'', ''Brugia malayi'' and ''Onchocerca volvulus''; *Hand-curated annotations describing the ...
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Institute Of Genomics And Integrative Biology
CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB) is a scientific research institute devoted primarily to biological research. It is a part of Council of Scientific and Industrial Research (CSIR), India. The institute was founded in 1977 as the Center for Biochemical Technology with a primary focus on biochemical research, but has since shifted its research focus to integrative biology. Location The Institute has two campuses in Delhi. The North Campus is the older of the two campuses and is in the campus of Delhi University, on Mall Road opposite to Jubilee Hall. The new campus is in South Delhi, on Mathura Road at Sukhdev Vihar. History IGIB was established in 1977 as the Center for Biochemical Technology (CBT). The Functional Genomics Unit was established in 1998 with the focus shifting from chemical to genomics research. The institute was renamed "Institute of Genomics and Integrative Biology" in 2002. Samir K. Brahmachari served as the founder director, ...
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Wiki
A wiki ( ) is a form of hypertext publication on the internet which is collaboratively edited and managed by its audience directly through a web browser. A typical wiki contains multiple pages that can either be edited by the public or limited to use within an organization for maintaining its internal knowledge base. Its name derives from the first user-editable website called " WikiWikiWeb," with "wiki" being a Hawaiian word meaning "quick." Wikis are powered by wiki software, also known as wiki engines. Being a form of content management system, these differ from other web-based systems such as blog software or static site generators in that the content is created without any defined owner or leader. Wikis have little inherent structure, allowing one to emerge according to the needs of the users. Wiki engines usually allow content to be written using a lightweight markup language and sometimes edited with the help of a rich-text editor. There are dozens of differ ...
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Google
Google LLC (, ) is an American multinational corporation and technology company focusing on online advertising, search engine technology, cloud computing, computer software, quantum computing, e-commerce, consumer electronics, and artificial intelligence (AI). It has been referred to as "the most powerful company in the world" by the BBC and is one of the world's List of most valuable brands, most valuable brands. Google's parent company, Alphabet Inc., is one of the five Big Tech companies alongside Amazon (company), Amazon, Apple Inc., Apple, Meta Platforms, Meta, and Microsoft. Google was founded on September 4, 1998, by American computer scientists Larry Page and Sergey Brin. Together, they own about 14% of its publicly listed shares and control 56% of its stockholder voting power through super-voting stock. The company went public company, public via an initial public offering (IPO) in 2004. In 2015, Google was reorganized as a wholly owned subsidiary of Alphabet Inc. Go ...
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BLAST (biotechnology)
In bioinformatics, BLAST (basic local alignment search tool) is an algorithm and program for comparing Primary structure, primary biological sequence information, such as the amino acid, amino-acid sequences of proteins or the nucleotides of DNA sequence, DNA and/or RNA sequences. A BLAST search enables a researcher to compare a subject protein or nucleotide sequence (called a query) with a library or database of sequences, and identify database sequences that resemble the query sequence above a certain threshold. For example, following the discovery of a previously unknown gene in the Mus musculus, mouse, a scientist will typically perform a BLAST search of the human genome to see if humans carry a similar gene; BLAST will identify sequences in the human genome that resemble the mouse gene based on similarity of sequence. Background BLAST is one of the most widely used bioinformatics programs for sequence searching. It addresses a fundamental problem in bioinformatics research ...
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China Zebrafish Resource Center
The China Zebrafish Resource Center (CZRC) is a non-profit organization located in 7 Donghu South Road, Wuhan, Focusing mainly on zebrafish resources. It was established in the Institute of Hydrobiology, Chinese Academy of Sciences, in October 2012, currently headed by the board chairman Meng Anming. Introduction CZRC is a non-profit organization jointly supported by the Ministry of Science and Technology of China, and the Chinese Academy of Sciences. CZRC mainly focuses on collecting existing zebrafish resources and developing new lines and technologies, with the purpose of providing resources, technical and informational support for colleagues in China China, officially the People's Republic of China (PRC), is a country in East Asia. With population of China, a population exceeding 1.4 billion, it is the list of countries by population (United Nations), second-most populous country after ... and overseas. Board of directors Honorary board chairman: Zhu Zuoyan Boar ...
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Biocurator
Biocuration is the field of List of life sciences, life sciences dedicated to organizing biomedical data, information and knowledge into structured formats, such as spreadsheets, Table (information), tables and Resource Description Framework, knowledge graphs. The biocuration of biomedical knowledge is made possible by the cooperative work of biocurators, Programmer, software developers and Bioinformatics, bioinformaticians and is at the base of the work of biological databases. Biocuration as a profession A biocurator is a professional scientist who Curator, curates, collects, annotates, and validates information that is disseminated by Biology, biological and model organism databases. It is a new profession, with the first mentions in the scientific literature dating of 2006 in the context of the work in databases like the Immune Epitope Database and Analysis Resource. Biocurators usually are Doctor of Philosophy, PhD-level with a mix of experiences in wet lab and computational ...
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Relational Database
A relational database (RDB) is a database based on the relational model of data, as proposed by E. F. Codd in 1970. A Relational Database Management System (RDBMS) is a type of database management system that stores data in a structured format using rows and columns. Many relational database systems are equipped with the option of using SQL (Structured Query Language) for querying and updating the database. History The concept of relational database was defined by E. F. Codd at IBM in 1970. Codd introduced the term ''relational'' in his research paper "A Relational Model of Data for Large Shared Data Banks". In this paper and later papers, he defined what he meant by ''relation''. One well-known definition of what constitutes a relational database system is composed of Codd's 12 rules. However, no commercial implementations of the relational model conform to all of Codd's rules, so the term has gradually come to describe a broader class of database systems, which at a ...
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