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Whitehead Institute
Whitehead Institute for Biomedical Research is a non-profit research institute located in Cambridge, Massachusetts, United States that is dedicated to improving human health through basic biomedical research. It was founded as a fiscally independent entity from the Massachusetts Institute of Technology (MIT), where its 18 members all hold faculty appointments in the MIT Department of Biology or the MIT Department of Bioengineering. Two members (Rudolf Jaenisch, 2010, and Robert Weinberg, 1997) are National Medal of Science recipients; ten have been elected to the National Academy of Sciences; and four have been elected to the National Academy of Medicine; six are Howard Hughes Medical Institute Investigators. In September 2019, Ruth Lehmann was announced as the new director of the Whitehead Institute for Biomedical Research, commencing July 2020 and succeeding David Page. History Whitehead Institute was founded in 1982 by industrialist and philanthropist Edwin C. “Jac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TIAA
The Teachers Insurance and Annuity Association of America-College Retirement Equities Fund (TIAA, formerly TIAA-CREF), is a Fortune 100 financial services organization that is the leading provider of financial services in the academic, research, medical, cultural and governmental fields. TIAA serves over 5 million active and retired employees participating at more than 15,000 institutions and has $1 trillion in combined assets under management with holdings in more than 50 countries (). Profile Long organized as a tax-exempt non-profit organization, a 1997 tax bill removed TIAA's tax exemption. It is now organized as a non-profit organization, the TIAA Board of Governors, with taxable subsidiaries; all profits are returned to policyholders. TIAA bought its Manhattan headquarters building, 730 Third Avenue, in 1955. It has major offices in Denver, Colorado; Charlotte, North Carolina; and Dallas, Texas; as well as 70 local offices throughout the U.S. In 2018, TIAA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Weinberg (biologist)
Robert Allan Weinberg (born November 11, 1942) is a biologist, Daniel K. Ludwig Professor for Cancer Research at Massachusetts Institute of Technology (MIT), director of the Ludwig Center of the MIT, and American Cancer Society Research Professor. His research is in the area of oncogenes and the genetic basis of human cancer. Robert Weinberg is also affiliated with the Broad Institute and is a founding member of the Whitehead Institute for Biomedical Research. Weinberg and Eric Lander, a colleague at M.I.T., are co-founders of Verastem, a biopharmaceutical company focused on discovering and developing drugs to treat cancer by targeting cancer stem cells. Career Weinberg earned SB in Biology from Massachusetts Institute of Technology in 1964 and PhD in Biology from the same institute in 1969. He was an instructor in biology at Stillman College in Tuscaloosa, Alabama (1965–1966), and a postdoc in Ernest Winocour's lab at the Weizmann Institute of Science (1969–1970) and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David Bartel
David P. Bartel is an American molecular biologist best known for his work on microRNAs. Bartel is a Professor of Biology at the Massachusetts Institute of Technology, Member of the Whitehead Institute, and investigator of the Howard Hughes Medical Institute (HHMI). Biography Bartel earned his B.A. degree in Biology from Goshen College in 1982 and his Ph.D. degree in Virology from Harvard University in 1993, under the mentorship of Jack W. Szostak. While in the Szostak lab, Bartel isolated the first ribozymes directly from random sequence, using ''in vitro'' evolution (among these, the Class I ligase). After he became independent at the Whitehead Institute, he further evolved this ribozyme to function as a RNA-dependent RNA polymerase to extend primers on external RNA templates, bolstering the "RNA world" theory. Bartel later shifted his research focus towards microRNA biology and in particular on understanding their regulatory functions. MicroRNAs are short pieces of RNA, abou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rubius Therapeutics
Rubén Doblas Gundersen (; born 13 February 1990), better known as elrubiusOMG or simply El Rubius (), is a Spanish-Norwegian YouTuber whose channel primarily consists of gameplays and vlogs. He has the most subscribers in Spain and is among the 50 channels with the most subscribers of the platform in the world. In 2014 he published ''El Libro Troll'' (English: ''The Troll Book''). During 2015 and 2017 he published a total of three comics from his Virtual Hero series. He also participated in an anime series based on the comics. A tweet from his official Twitter account was the most retweeted tweet in the world since 2016. The tweet was often retweeted. In 2016, ''Time'' magazine included him in its list of "next generation leaders" and named him an "online conqueror". In 2018, he obtained the world record of viewers live during an online YouTube broadcast for an tournament of the ''Fortnite'' video game. He is one of the most popular streamers on Twitch, with the third-most ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ironwood Pharmaceuticals
Ironwood Pharmaceuticals, Inc is a publicly traded pharmaceutical company. It was originally called Microbia, Inc. Microbia was founded by postdocs from the lab of Gerald Fink at the Whitehead Institute to commercialize approaches that had been developed in the lab to improve industrial fermentation of fungi, to genetically engineer them to produce secondary metabolites more efficiently or to produce new ones as leads for drug discovery or as products for use in industry, and to identify drug targets in fungi for antifungal drug discovery. In 2002 the company hired John Talley to lead their antifungal drug discovery efforts, which at the time were focused on identifying small molecules that could inhibit fungal invasins, along with Mark Currie who had also worked at Searle division of Monsanto with Talley, and then had gone to Sepracor, and also Richard Bailey, who had run Monsanto's nutritional business. Currie directed the efforts that led to the discovery of linacloti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genzyme
Genzyme was an American biotechnology company based in Cambridge, Massachusetts. Since its acquisition in 2011, Genzyme (also known as Genzyme Transgenics Corp or GTC Biotherapeutics) has been a fully owned subsidiary of Sanofi. In 2010, Genzyme was the world’s third-largest biotechnology company, employing more than 11,000 people around the world. As a subsidiary of Sanofi, Genzyme has a presence in approximately 65 countries, including 17 manufacturing facilities and 9 genetic-testing laboratories. Its products are also sold in 90 countries. In 2007, Genzyme generated $3.8 billion in revenue with more than 25 products on the market. In 2006 and 2007, Genzyme was named one of ''Fortune'' magazine’s “100 Best Companies to Work for”. The company donated $83 million worth of products worldwide; in 2006, it made $11 million in cash donations. In 2005, Genzyme was awarded the National Medal of Technology, the highest level of honor awarded by the president of the United State ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals, Inc. is an American biopharmaceutical company focused on the discovery, development and commercialization of RNA interference (RNAi) therapeutics for genetically defined diseases. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts. In 2016, ''Forbes'' included the company on its "100 Most Innovative Growth Companies" list. History The company is a spin-off from the Max Planck Institute for Biophysical Chemistry. In 2002, Alnylam was founded by scientists Phillip Sharp, Paul Schimmel, David Bartel, Thomas Tuschl, and Phillip Zamore, and by investors Christoph Westphal and John Kennedy Clarke; John Maraganore was the founding CEO. The company was named after Alnilam, a star in Orion’s belt. The spelling was modified to make it unique. In 2003, the firm merged with the German pharmaceutical company, Ribopharma AG. The newly formed company also received $24.6 million in funding from private-equity firms. On February 27, 20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Scientist (magazine)
''The Scientist'' is a professional magazine intended for life scientists. Coverage includes articles on recently published research papers, current research, techniques, important career news, profiles of established and up and coming scientists, publishing, research integrity and best practices, as well as other columns and reports of interest to its readers. The editor-in-chief is Bob Grant. Overview The main purpose of the magazine is to provide print and online coverage of the latest developments in life sciences research, technology, careers, and business. Subject matter covered by the magazine includes: groundbreaking research, industry innovations, careers, financial topics, economics of science, scientific ethics, profiles of scientists, lab tools, scientific publishing, techniques, product spotlight, and guides History ''The Scientist'' was founded by Eugene Garfield in 1986. In 1988, Garfield sold ''The Scientist'', part of the ''Institute for Scientific Infor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Citation Impact
Citation impact is a measure of how many times an academic journal article or book or author is cited by other articles, books or authors. Citation counts are interpreted as measures of the impact or influence of academic work and have given rise to the field of bibliometrics or scientometrics, specializing in the study of patterns of academic impact through citation analysis. The journal impact factor, the two-year average ratio of citations to articles published, is a measure of the importance of journals. It is used by academic institutions in decisions about academic tenure, promotion and hiring, and hence also used by authors in deciding which journal to publish in. Citation-like measures are also used in other fields that do ranking, such as Google's PageRank algorithm, software metrics, college and university rankings, and business performance indicators. Article-level One of the most basic citation metrics is how often an article was cited in other articles, books, or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eric Lander
Eric Steven Lander (born February 3, 1957) is an American mathematician and geneticist who served as the 11th director of the Office of Science and Technology Policy and Science Advisor to the President, serving on the presidential Cabinet. Lander is a professor of biology at the Massachusetts Institute of Technology (MIT), a professor of systems biology at Harvard Medical School, a former member of the Whitehead Institute, and the founding director of the Broad Institute. He is a 1987 MacArthur Fellow and Rhodes Scholar. Lander co-chaired President Barack Obama's Council of Advisors on Science and Technology. Lander announced he would resign from the Biden Administration effective February 18, 2022 after allegations surfaced he had engaged in bullying and abusive conduct directed against his subordinates and other White House staff. Early life and education Lander was born in Brooklyn, New York City, to Jewish parents, the son of Rhoda G. Lander, a social studies t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Broad Institute
The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States. The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it partners with the Massachusetts Institute of Technology, Harvard University, and the five Harvard teaching hospitals. History The Broad Institute evolved from a decade of research collaborations among MIT and Harvard scientists. One cornerstone was the Center for Genome Research of Whitehead Institute at MIT. Founded in 1982, the Whitehead became a major center for genomics and the Human Genome Project. As early as 1995, scientists at the Whitehead started pilot projects in genomic medicine, forming an unofficial collaborative network among young scientists interested in genomic approaches to cancer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It remains the world's largest collaborative biological project. Planning started after the idea was picked up in 1984 by the US government, the project formally launched in 1990, and was declared essentially complete on April 14, 2003, but included only about 85% of the genome. Level "complete genome" was achieved in May 2021, with a remaining only 0.3% bases covered by potential issues. The final gapless assembly was finished in January 2022. Funding came from the United States government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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