UppP
UPPP may refer to: * Undecaprenyl-diphosphatase, an enzyme * Uvulopalatopharyngoplasty Uvulopalatopharyngoplasty (abbreviated as UPPP or UP3) is a type of sleep surgery, which are surgical procedures for sleep-related breathing disorders, especially obstructive sleep apnea (OSA). Uvulopalatopharyngoplasty involves removal and/or rem ...

Undecaprenyl-diphosphatase
In enzymology, an undecaprenyl-diphosphatase () is an enzyme that catalyzes the chemical reaction :undecaprenyl diphosphate + H2O \rightleftharpoons undecaprenyl phosphate + phosphate Thus, the two substrates of this enzyme are undecaprenyl diphosphate and H2O, whereas its two products are undecaprenyl phosphate and phosphate. The enzymatic activity is enhanced by divalent cations, particularly Ca2+. In many bacteria, this enzyme is a membrane protein that participates in peptidoglycan biosynthesis. The enzyme has been implicated in conferring resistance to the antibiotic bacitracin. Nomenclature This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is undecaprenyl-diphosphate phosphohydrolase. Other names in common use include Undecaprenyl-pyrophosphate phosphatase (Uppp), UPP phosphatase, BacA, C55-isoprenyl diphosphatase, C55-isoprenyl pyrophosphatas ...
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