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Spiral Ganglion
The spiral (cochlear) ganglion is a group of neuron cell bodies in the modiolus, the conical central axis of the cochlea. These bipolar neurons innervate the hair cells of the organ of Corti. They project their axons to the ventral and dorsal cochlear nuclei as the cochlear nerve, a branch of the vestibulocochlear nerve (CN VIII). Structure Neurons whose cell bodies lie in the spiral ganglion are strung along the bony core of the cochlea, and send fibers (axons) into the central nervous system (CNS). These bipolar neurons are the first neurons in the auditory system to fire an action potential, and supply all of the brain's auditory input. Their dendrites make synaptic contact with the base of hair cells, and their axons are bundled together to form the auditory portion of eighth cranial nerve. The number of neurons in the spiral ganglion is estimated to be about 35,000–50,000. Two apparent subtypes of spiral ganglion cells exist. Type I spiral ganglion cells com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cochlear Duct
Cochlear, the adjective form of cochlea, may refer to: * Cochlear implant, a sensory aid for the deaf * Cochlear nuclei, the ventral cochlear nucleus and the dorsal (or lateral) cochlear nucleus * Vestibular-cochlear or Vestibulocochlear nerve, the eighth cranial nerve * Cochlear nerve, a division of the eighth cranial nerve * Cochlear aqueduct, or aqueduct of cochlea, a communication between the perilymphatic space and the subarachnoid space * Cochlear artery, a division of the internal auditory artery * Cochlea, part of the Labyrinth (inner ear) * Cochlear duct, also known as the scala media, the endolymph-filled part of the cochlea * Cochlear, an alternate term for the spoon (liturgy) used in the Eastern Orthodox Church in serving the sacramental wine, sometimes with a particle of the sacramental bread * The spoon-like tip of the scape found on the epigyne of some female spiders * Cochlear Limited, manufacturer of Nucleus Cochlear Implant * Cochlear Bone Anchored Solu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synapse
In the nervous system, a synapse is a structure that allows a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or a target effector cell. Synapses can be classified as either chemical or electrical, depending on the mechanism of signal transmission between neurons. In the case of electrical synapses, neurons are coupled bidirectionally with each other through gap junctions and have a connected cytoplasmic milieu. These types of synapses are known to produce synchronous network activity in the brain, but can also result in complicated, chaotic network level dynamics. Therefore, signal directionality cannot always be defined across electrical synapses. Chemical synapses, on the other hand, communicate through neurotransmitters released from the presynaptic neuron into the synaptic cleft. Upon release, these neurotransmitters bind to specific receptors on the postsynaptic membrane, inducing an electrical or chemical response in the target neuron ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vestibulocochlear Nerve
The vestibulocochlear nerve or auditory vestibular nerve, also known as the eighth cranial nerve, cranial nerve VIII, or simply CN VIII, is a cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain. Through olivocochlear fibers, it also transmits motor and modulatory information from the superior olivary complex in the brainstem to the cochlea. Structure The vestibulocochlear nerve consists mostly of bipolar neurons and splits into two large divisions: the cochlear nerve and the vestibular nerve. Cranial nerve 8, the vestibulocochlear nerve, goes to the middle portion of the brainstem called the pons (which then is largely composed of fibers going to the cerebellum). The 8th cranial nerve runs between the base of the pons and medulla oblongata (the lower portion of the brainstem). This junction between the pons, medulla, and cerebellum that contains the 8th nerve is called the cerebellopontine angle. The vestibulocochlea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sensory Ganglia
A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. The axons of dorsal root ganglion neurons are known as afferents. In the peripheral nervous system, afferents refer to the axons that relay sensory information into the central nervous system (i.e. the brain and the spinal cord). Structure The neurons comprising the dorsal root ganglion are of the pseudo-unipolar type, meaning they have a cell body (soma) with two branches that act as a single axon, often referred to as a ''distal process'' and a ''proximal process''. Unlike the majority of neurons found in the central nervous system, an action potential in posterior root ganglion neuron may initiate in the ''distal process'' in the periphery, bypass the cell body, and continue to propagate along the ''proximal proces ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Auditory System
The auditory system is the sensory system for the sense of hearing. It includes both the ear, sensory organs (the ears) and the auditory parts of the sensory system. System overview The outer ear funnels sound vibrations to the eardrum, increasing the sound pressure in the middle frequency range. The Middle ear, middle-ear ossicles further amplify the vibration pressure roughly 20 times. The base of the stapes couples vibrations into the cochlea via the oval window, which vibrates the perilymph liquid (present throughout the inner ear) and causes the round window to bulb out as the oval window bulges in. Vestibular duct, Vestibular and tympanic ducts are filled with perilymph, and the smaller cochlear duct between them is filled with endolymph, a fluid with a very different ion concentration and voltage. Vestibular duct perilymph vibrations bend organ of Corti outer cells (4 lines) causing prestin to be released in cell tips. This causes the cells to be chemically elongated an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of New England, Maine
The University of New England (UNE) is a private university, private research university in Portland, Maine, Portland and Biddeford, Maine, Biddeford, Maine, United States. It traces it historical origins to 1831 when Westbrook College, Westbrook Seminary opened on what is now the UNE Portland Campus. UNE is the largest private university in the state of Maine and the largest educator of healthcare professionals for Maine. It is organized into five colleges that combine to offer more than 70 undergraduate, graduate, online, and professional degrees. The university is Carnegie Classification of Institutions of Higher Education, classified among "R2: Doctoral Universities – High research activity." History In 1939, a boys-only high school and junior college called the College Séraphique was founded in Biddeford by Father Decary and the Franciscan friar of St. Andre's parish. In 1952, the school changed its name to St. Francis College and began granting bachelor's degrees wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ Of Corti
The organ of Corti, or spiral organ, is the receptor organ for hearing and is located in the mammalian cochlea. This highly varied strip of epithelial cells allows for transduction of auditory signals into nerve impulses' action potential. Transduction occurs through vibrations of structures in the inner ear causing displacement of cochlear fluid and movement of hair cells at the organ of Corti to produce electrochemical signals.The Ear Pujol, R., Irving, S., 2013 Italian anatomist Alfonso Giacomo Gaspare Corti (1822–1876) discovered the organ of Corti in 1851. The structure evolved from the basilar p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brainstem
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem. The brainstem is very small, making up around only 2.6 percent of the brain's total weight. It has the critical roles of regulating heart and respiratory system, respiratory function, helping to control heart rate and breathing rate. It also provides the main motor and sensory nerve supply to the face and neck via the cranial nerves. Ten pairs of cranial nerves come from the brainstem. Other roles include the regulation of the central nervous system and the body's sleep cycle. It is also of prime importance in the conveyance of motor and sensory pathways from the rest of the brain to the body, and from the b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vestibular Ganglion
The vestibular ganglion (also Scarpa's ganglion) is a collection of cell bodies belonging to first order sensory neurons of the vestibular nerve. It is located within the internal auditory canal. Anatomy Surrounding structure The superior and inferior divisions of the vestibular nerve meet at the ganglion. Thereon, the fibers of second-order neurons of the vestibular nerve merge with those of the cochlear nerve (whose first-order neurons have already synapsed at the spiral ganglion) to proceed towards the CNS as a single unified vestibulocochlear nerve (cranial nerve VIII). Internal structure The ganglion contains the cell bodies of bipolar neurons whose peripheral processes form synaptic contact with hair cells of the vestibular sensory end organs. These include hair cells of the cristae ampullaris of the semicircular duct, and the maculae of the utricle and saccule. Development As with the entirety of the inner ear organs and associated sensory organs, the vestibu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Auditory Vesicle
Otic vesicle, or auditory vesicle, consists of either of the two sac-like invaginations formed and subsequently closed off during embryonic development. It is part of the neural ectoderm, which will develop into the membranous labyrinth of the inner ear. This labyrinth is a continuous epithelium, giving rise to the vestibular system and auditory components of the inner ear. During the earlier stages of embryogenesis, the otic placode invaginates to produce the otic cup. Thereafter, the otic cup closes off, creating the otic vesicle. Once formed, the otic vesicle will reside next to the neural tube medially, and on the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across vertebrates, although there is much variation in timing and stages. Patterning during morphogenesis into the distinctive inner ear structures is determined by homeobox transcr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ganglion
A ganglion (: ganglia) is a group of neuron cell bodies in the peripheral nervous system. In the somatic nervous system, this includes dorsal root ganglia and trigeminal ganglia among a few others. In the autonomic nervous system, there are both sympathetic and parasympathetic ganglia which contain the cell bodies of postganglionic sympathetic and parasympathetic neurons respectively. A pseudoganglion looks like a ganglion, but only has nerve fibers and has no nerve cell bodies. Structure Ganglia are primarily made up of somata and dendritic structures, which are bundled or connected. Ganglia often interconnect with other ganglia to form a complex system of ganglia known as a plexus. Ganglia provide relay points and intermediary connections between different neurological structures in the body, such as the peripheral and central nervous systems. Among vertebrates there are three major groups of ganglia: * Dorsal root ganglia (also known as the spinal ganglia) contai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rudiment (biology)
Vestigiality is the retention, during the process of evolution, of genetically determined structures or attributes that have lost some or all of the ancestral function in a given species. Assessment of the vestigiality must generally rely on comparison with homologous features in related species. The emergence of vestigiality occurs by normal evolutionary processes, typically by loss of function of a feature that is no longer subject to positive selection pressures when it loses its value in a changing environment. The feature may be selected against more urgently when its function becomes definitively harmful, but if the lack of the feature provides no advantage, and its presence provides no disadvantage, the feature may not be phased out by natural selection and persist across species. Examples of vestigial structures (also called degenerate, atrophied, or rudimentary organs) are the loss of functional wings in island-dwelling birds; the human vomeronasal organ; and the h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
