Shiga Toxin
Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages. The toxins are named after Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by '' Shigella dysenteriae''. Shiga-like toxin (SLT) is a historical term for similar or identical toxins produced by ''Escherichia coli''. The most common sources for Shiga toxin are the bacteria ''S. dysenteriae'' and some serotypes of ''Escherichia coli'' (shigatoxigenic or STEC), which include serotypes O157:H7, and O104:H4. Nomenclature Microbiologists use many terms to describe Shiga toxin and differentiate more than one unique form. Many of these terms are used interchangeably. # Shiga toxin type 1 and type 2 (Stx-1 and 2) are the Shiga toxins produced by some'' E. coli'' strains. Stx-1 is identical to Stx of ''Shigella'' spp. or differs by only one amino acid. Stx-2 shares 55% amino acid homology w ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chlorocebus
''Chlorocebus'' is a genus of medium-sized primates from the family of Old World monkeys. Six species are currently recognized, although some people classify them all as a single species with numerous subspecies. Either way, they make up the entirety of the genus ''Chlorocebus''. Confusingly, the terms "vervet monkey" and "green monkey" are sometimes used to refer to the whole genus ''Chlorocebus'', though they also refer more precisely to species ''vervet monkey, Chlorocebus pygerythrus'' and ''green monkey, Chlorocebus sabaeus'', respectively, neither of which is the type species for ''Chlorocebus''. This article uses the term ''Chlorocebus'' consistently for the genus and the common names only for the species. The native range (biology), range of these monkeys is sub-Saharan Africa from Senegal and Ethiopia south to South Africa. However, in previous centuries, a number of them were taken as pets by early Caribbean settlers and slave traders, and were transported across the At ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Species
A species () is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction. It is the basic unit of Taxonomy (biology), classification and a taxonomic rank of an organism, as well as a unit of biodiversity. Other ways of defining species include their karyotype, DNA sequence, morphology (biology), morphology, behaviour, or ecological niche. In addition, palaeontologists use the concept of the chronospecies since fossil reproduction cannot be examined. The most recent rigorous estimate for the total number of species of eukaryotes is between 8 and 8.7 million. About 14% of these had been described by 2011. All species (except viruses) are given a binomial nomenclature, two-part name, a "binomen". The first part of a binomen is the name of a genus to which the species belongs. The second part is called the specific name (zoology), specific name or the specific ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cell (biology)
The cell is the basic structural and functional unit of all life, forms of life. Every cell consists of cytoplasm enclosed within a Cell membrane, membrane; many cells contain organelles, each with a specific function. The term comes from the Latin word meaning 'small room'. Most cells are only visible under a light microscope, microscope. Cells Abiogenesis, emerged on Earth about 4 billion years ago. All cells are capable of Self-replication, replication, protein synthesis, and cell motility, motility. Cells are broadly categorized into two types: eukaryotic cells, which possess a Cell nucleus, nucleus, and prokaryotic, prokaryotic cells, which lack a nucleus but have a nucleoid region. Prokaryotes are single-celled organisms such as bacteria, whereas eukaryotes can be either single-celled, such as amoebae, or multicellular organism, multicellular, such as some algae, plants, animals, and fungi. Eukaryotic cells contain organelles including Mitochondrion, mitochondria, which ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Receptor (biochemistry)
In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and Signal_transduction, transduce signals that may be integrated into biological systems. These signals are typically chemical messengers which bind to a receptor and produce physiological responses, such as a change in the electrophysiology, electrical activity of a cell. For example, GABA, an inhibitory neurotransmitter, inhibits electrical activity of neurons by binding to GABAA receptor, GABA receptors. There are three main ways the action of the receptor can be classified: relay of signal, amplification, or integration. Relaying sends the signal onward, amplification increases the effect of a single ligand (biochemistry), ligand, and integration allows the signal to be incorporated into another biochemical pathway. Receptor proteins can be classified by their location. Cell surface receptors, also known as transmembrane receptors, include ligand-gated ion channels, G prote ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Type Strain
The International Code of Nomenclature of Prokaryotes (ICNP) or Prokaryotic Code, formerly the International Code of Nomenclature of Bacteria (ICNB) or Bacteriological Code (BC), governs the scientific names for Bacteria and Archaea.P. H. A. Sneath, 2003. A short history of the Bacteriological CodURL It denotes the rules for naming taxa of bacteria, according to their relative rank. As such it is one of the nomenclature codes of biology. Originally the ''International Code of Botanical Nomenclature'' dealt with bacteria, and this kept references to bacteria until these were eliminated at the 1975 International Botanical Congress. An early Code for the nomenclature of bacteria was approved at the 4th International Congress for Microbiology in 1947, but was later discarded. The latest version to be printed in book form is the 1990 Revision, but the book does not represent the current rules. The 2008 and 2022 Revisions have been published in the '' International Journal of Systematic ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Escherichia
''Escherichia'' ( ) is a genus of Gram-negative, non-Endospore, spore-forming, Facultative anaerobic organism, facultatively anaerobic, rod-shaped bacteria from the family Enterobacteriaceae. In those species which are inhabitants of the gastrointestinal tracts of warm-blooded animals, ''Escherichia'' species provide a portion of the microbially derived vitamin K for their host. A number of the species of ''Escherichia'' are pathogenic. The genus is named after Theodor Escherich, the discoverer of ''Escherichia coli''. ''Escherichia'' are facultative aerobes, with both aerobic and anaerobic growth, and an optimum temperature of 37 °C. ''Escherichia'' are usually motile by Flagellum, flagella, produce gas from fermentable carbohydrates, and do not decarboxylate lysine or hydrolyze arginine. Species include ''Escherichia albertii, E. albertii'', ''Escherichia fergusonii, E. fergusonii'', ''Escherichia hermannii, E. hermannii'', ''Escherichia ruysiae, E. ruysiae'', ''Escherichia ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Subgenus
In biology, a subgenus ( subgenera) is a taxonomic rank directly below genus. In the International Code of Zoological Nomenclature, a subgeneric name can be used independently or included in a species name, in parentheses, placed between the generic name and the specific epithet: e.g. the tiger cowry of the Indo-Pacific, ''Cypraea'' (''Cypraea'') ''tigris'' Linnaeus, which belongs to the subgenus ''Cypraea'' of the genus ''Cypraea''. However, it is not mandatory, or even customary, when giving the name of a species, to include the subgeneric name. In the International Code of Nomenclature for algae, fungi, and plants The ''International Code of Nomenclature for algae, fungi, and plants'' (ICN or ICNafp) is the set of rules and recommendations dealing with the formal botanical names that are given to plants, fungi and a few other groups of organisms, all tho ... (ICNafp), the subgenus is one of the possible subdivisions of a genus. There is no limit to the number of divisio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Shigella
''Shigella'' is a genus of bacteria that is Gram negative, facultatively anaerobic, non–spore-forming, nonmotile, rod shaped, and is genetically nested within ''Escherichia''. The genus is named after Kiyoshi Shiga, who discovered it in 1897. ''Shigella'' causes disease in primates, but not in other mammals; it is the causative agent of human shigellosis. It is only naturally found in humans and gorillas. During infection, it typically causes dysentery. ''Shigella'' is a leading cause of bacterial diarrhea worldwide, with 80–165 million annual cases (estimated) and 74,000 to 600,000 deaths. It is one of the top four pathogens that cause moderate-to-severe diarrhea in African and South Asian children. Classification ''Shigella'' species are classified by three serogroups and one serotype: * Serogroup ''A'': '' S. dysenteriae'' (15 serotypes) * Serogroup ''B'': '' S. flexneri'' (9 serotypes) * Serogroup ''C'': '' S. boydii'' (19 serotypes) * Serogroup ''D'': '' S. so ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Phylogenetic
In biology, phylogenetics () is the study of the evolutionary history of life using observable characteristics of organisms (or genes), which is known as phylogenetic inference. It infers the relationship among organisms based on empirical data and observed heritable traits of DNA sequences, protein amino acid sequences, and morphology. The results are a phylogenetic tree—a diagram depicting the hypothetical relationships among the organisms, reflecting their inferred evolutionary history. The tips of a phylogenetic tree represent the observed entities, which can be living taxa or fossils. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the taxa represented on the tree. An unrooted tree diagram (a network) makes no assumption about directionality of character state transformation, and does not show the origin or "root" of the taxa in question. In addition to their use for inferring phylogenetic pa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Transduction (genetics)
Transduction is the process by which foreign DNA is introduced into a cell by a virus or viral vector. An example is the viral transfer of DNA from one bacterium to another and hence an example of horizontal gene transfer. Transduction does not require physical contact between the cell donating the DNA and the cell receiving the DNA (which occurs in conjugation), and it is DNase resistant ( transformation is susceptible to DNase). Transduction is a common tool used by molecular biologists to stably introduce a foreign gene into a host cell's genome (both bacterial and mammalian cells). Discovery (bacterial transduction) Transduction was discovered in ''Salmonella'' by Norton Zinder and Joshua Lederberg at the University of Wisconsin–Madison in 1952. In the lytic and lysogenic cycles Transduction happens through either the lytic cycle or the lysogenic cycle. When bacteriophages (viruses that infect bacteria) that are lytic infect bacterial cells, they harness the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chromosome
A chromosome is a package of DNA containing part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells, the most important of these proteins are the histones. Aided by chaperone proteins, the histones bind to and condense the DNA molecule to maintain its integrity. These eukaryotic chromosomes display a complex three-dimensional structure that has a significant role in transcriptional regulation. Normally, chromosomes are visible under a light microscope only during the metaphase of cell division, where all chromosomes are aligned in the center of the cell in their condensed form. Before this stage occurs, each chromosome is duplicated ( S phase), and the two copies are joined by a centromere—resulting in either an X-shaped structure if the centromere is located equatorially, or a two-armed structure if the centromere is located distally; the jo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |