Methylserotonin
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Methylserotonin
Methylserotonin, or methyl-5-hydroxytryptamine (methyl-5-HT), may refer to: * 5-Methoxytryptamine (5-MeO-T; ''O''-methylserotonin; ''O''-Me-5-HT) * 2-Methyl-5-hydroxytryptamine (2-Me-5-HT; 2-methylserotonin) * α-Methylserotonin (α-methyl-5-hydroxytryptamine; α-methyl-5-HT; α-Me-5-HT) * ''N''-Methylserotonin (NMS; ''N''-methyl-5-hydroxytryptamine; ''N''-Me-5-HT) See also * Dimethylserotonin * Trimethylserotonin * Tetramethylserotonin * Methyltryptamine Methyltryptamine (MT) may refer to: * ''N''-Methyltryptamine (NMT; monomethyltryptamine) * α-Methyltryptamine (AMT or αMT; Indopan) * 1-Methyltryptamine (1-Me-T; PAL-637) * 2-Methyltryptamine (2-Me-T) * 5-Methyltryptamine (5-Me-T; PAL-22) See ... {{Chemistry index 5-Hydroxytryptamines Methyl compounds ...
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N-Methylserotonin
''N''-Methylserotonin, also known as norbufotenin or as 5-hydroxy-''N''-methyltryptamine (5-HO-NMT, is a tryptamine alkaloid. Chemically, it is a derivative of serotonin in which a methyl group resides at its alkyl amine. It is also called ''N''ω-methylserotonin (''N''ω-methyl-5-hydroxytryptamine) to distinguish it from tryptamine-derived compounds in which a methyl group is bonded to the nitrogen atom of the indole group. ''N''-Methylserotonin is found in plants, animals, and fungi. These include the plants, ''Actaea racemosa'' (black cohosh) and ''Zanthoxylum piperitum'', the Green and Golden Bell Frog, '' Litoria aurea'', and ''Amanita'' mushrooms. Pharmacology The compound binds to several serotonin receptors, including the 5-HT7 and 5-HT1A receptors, with high affinity ( IC50 ≤ 2 nM) and selectivity, and displays agonist activity. It also shows lower affinity for other serotonin receptors. Besides its direct interaction with the serotonin receptors, ''N''-methylsero ...
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5-Methoxytryptamine
5-Methoxytryptamine (5-MT, 5-MeO-T, or 5-OMe-T), also known as serotonin methyl ether or ''O''-methylserotonin and as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. It has been shown to occur naturally in the body in low levels, especially in the pineal gland. It is formed via ''O''-methylation of serotonin or ''N''-deacetylation of melatonin. 5-MT is a highly potent and non-selective serotonin receptor agonist and shows serotonergic psychedelic-like effects in animals. However, it is inactive in humans, at least orally, likely due to rapid metabolism by monoamine oxidase (MAO). The levels and effects of 5-MT are dramatically potentiated by monoamine oxidase inhibitors (MAOIs) in animals. Biosynthesis 5-MT can be formed by ''O''-methylation of serotonin mediated by hydroxyindole ''O''-methyltransferase (HIOMT) or by ''N''-deacetylation of melatonin. It is also a precursor of 5-MeO-DMT in some species. Pharmacology Ph ...
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Dimethylserotonin
Dimethylserotonin (DMS) may refer to: * Bufotenin (''N'',''N''-dimethylserotonin) * 5-MeO-AMT (α,''O''-dimethylserotonin) * 5-MeO-NMT (''O'',''N''-dimethylserotonin) See also * Methylserotonin * Trimethylserotonin * Tetramethylserotonin * Dimethyltryptamine Dimethyltryptamine (DMT), also known as ''N'',''N''-dimethyltryptamine (''N'',''N''-DMT), is a Psychedelic drug, serotonergic hallucinogen and Investigational New Drug, investigational drug of the substituted tryptamine, tryptamine family tha ... {{Chemistry index 5-Hydroxytryptamines ...
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Trimethylserotonin
Trimethylserotonin (TMS) may refer to: * Bufotenidine (''N'',''N'',''N''-trimethylserotonin) * 5-MeO-DMT 5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine), also known as ''O''-methylbufotenin or mebufotenin (), is a naturally occurring psychedelic of the tryptamine family. It is found in a wide variety of plant species, and is also secreted by ... (''N'',''N'',''O''-trimethylserotonin) * α,''N'',''O''-TMS (α,''N'',''O''-trimethylserotonin) * α,''N'',''N''-TMS (α,''N'',''N''-trimethylserotonin) See also * Methylserotonin * Dimethylserotonin * Tetramethylserotonin * Trimethyltryptamine {{Chemistry index 5-Hydroxytryptamines ...
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Tetramethylserotonin
Tetramethylserotonin (TeMS) may refer to: * Α,N,N,O-TeMS (''N'',''N'',''O'',α-tetramethylserotonin) * 5-Methoxy-2,N,N-trimethyltryptamine (''N'',''N'',α,2-tetramethylserotonin) * 5-Methoxy-7,N,N-trimethyltryptamine (''N'',''N'',α,7-tetramethylserotonin) See also * Methylserotonin * Dimethylserotonin * Trimethylserotonin Trimethylserotonin (TMS) may refer to: * Bufotenidine (''N'',''N'',''N''-trimethylserotonin) * 5-MeO-DMT 5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine), also known as ''O''-methylbufotenin or mebufotenin (), is a naturally occurring psy ... {{Chemistry index 5-Hydroxytryptamines ...
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Methyltryptamine
Methyltryptamine (MT) may refer to: * ''N''-Methyltryptamine (NMT; monomethyltryptamine) * α-Methyltryptamine (AMT or αMT; Indopan) * 1-Methyltryptamine (1-Me-T; PAL-637) * 2-Methyltryptamine (2-Me-T) * 5-Methyltryptamine (5-Me-T; PAL-22) See also * Dimethyltryptamine * Ethyltryptamine * Trimethyltryptamine * Methylethyltryptamine Methylethyltryptamine (MET), also known as ''N''-methyl-''N''-ethyltryptamine (''N'',''N''-MET), is a serotonergic psychedelic of the tryptamine family. It is closely related to dimethyltryptamine (DMT) and to diethyltryptamine (DET). The drug ... * Methylserotonin {{Chemistry index Methyl compounds Tryptamines ...
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2-Methyl-5-hydroxytryptamine
2-Methyl-5-hydroxytryptamine (2-methylserotonin, 2-methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts as a moderately selective full agonist at the 5-HT3 receptor. See also * 5-Carboxamidotryptamine * 5-Methoxytryptamine 5-Methoxytryptamine (5-MT, 5-MeO-T, or 5-OMe-T), also known as serotonin methyl ether or ''O''-methylserotonin and as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. It has been shown to oc ... * α-Methyl-5-hydroxytryptamine References 5-HT3 agonists 2-Alkyltryptamines 5-Hydroxytryptamines Serotonin receptor agonists {{nervous-system-drug-stub ...
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