Jerry Avorn
''Jerry Avorn (born February 13, 1948) is a professor of medicine at Harvard Medical School and Chief Emeritus of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women’s Hospital. He founded one of the largest programs using health care utilization data to track medication use and outcomes, and invented the practice of "academic detailing" in which pharmacists, nurses, and physicians educate doctors about cost-effective prescribing practices using the same tactics that drug companies employ to market their products. He received a B.A. from Columbia University in 1969 and M.D. from Harvard Medical School in 1974. Early life and education Avorn was born in 1948, in New York City and grew up in Rockaway, Queens. While attending Columbia University during the opposition to the Vietnam War and American civil rights movement, he was a campus activist against the Vietnam War with his investigative journalism for the ''Columbia Daily Spectator''. In the summer ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts is a teaching hospital of Harvard Medical School and one of the founding members of Beth Israel Lahey Health. It was formed out of the 1996 merger of Beth Israel Hospital (founded in 1916 by the Jewish community) and New England Deaconess Hospital (founded in 1896 by Methodist deaconesses). Among independent teaching hospitals, Beth Israel Deaconess Medical Center has ranked in the top three recipients of biomedical research funding from the National Institutes of Health. Research funding totals nearly $200 million annually. BIDMC researchers run more than 850 active sponsored projects and 200 clinical trials. The Harvard-Thorndike General Clinical Research Center, the oldest clinical research laboratory in the United States, has been located on this site since 1973. Overview BIDMC is one of the largest hospitals in New England, is affiliated with Joslin Diabetes Center and is a research partner of Dana-Fa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1948 Births
Events January * January 1 ** The General Agreement on Tariffs and Trade (GATT) is inaugurated. ** The current Constitutions of Constitution of Italy, Italy and of Constitution of New Jersey, New Jersey (both later subject to amendment) go into effect. ** The railways of Britain are nationalized, to form British Railways. * January 4 – British rule in Burma, Burma gains its independence from the United Kingdom, becoming an independent republic, named the 'Post-independence Burma (1948–1962), Union of Burma', with Sao Shwe Thaik as its first President and U Nu its first Prime Minister. * January 5 – In the United States: ** Warner Brothers shows the first color newsreel (''Tournament of Roses Parade'' and the ''Rose Bowl Game''). ** The first Kinsey Reports, Kinsey Report, ''Sexual Behavior in the Human Male'', is published. * January 7 – Mantell UFO incident: Kentucky Air National Guard pilot Thomas Mantell crashes while in pursuit of an unidentified fl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rofecoxib
Rofecoxib is a COX-2-selective nonsteroidal anti-inflammatory drug (NSAID). It was marketed by Merck & Co. to treat osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, acute pain conditions, migraine, and dysmenorrhea. Rofecoxib was approved in the US by the US Food and Drug Administration (FDA) in May 1999, and was marketed under the brand names Vioxx, Ceoxx, and Ceeoxx. Rofecoxib was available by prescription in both tablets and as an oral suspension. Rofecoxib gained widespread use among physicians treating patients with arthritis and other conditions causing chronic or acute pain. Worldwide, over 80 million people were prescribed rofecoxib at some time. In September 2004, Merck voluntarily withdrew rofecoxib from the market because of concerns about increased risk of heart attack and stroke associated with long-term, high-dosage use. Merck withdrew the drug after disclosures that it withheld information about rofecoxib's risks from doctors and patients for ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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COX-2 Inhibitor
Cyclooxygenase-2 inhibitors (COX-2 inhibitors), also known as coxibs, are a type of nonsteroidal anti-inflammatory drug (NSAID) that directly target cyclooxygenase-2 (COX-2), an enzyme responsible for inflammation and pain. Targeting selectivity for COX-2 reduces the risk of peptic ulceration and is the main feature of celecoxib, rofecoxib, and other members of this drug class. After several COX-2–inhibiting drugs were approved for marketing, data from clinical trials revealed that COX-2 inhibitors caused a significant increase in heart attacks and strokes, with some drugs in the class having worse risks than others. Rofecoxib (sold under the brand name Vioxx) was taken off the market in 2004 because of these concerns, while celecoxib (sold under the brand name Celebrex) and traditional NSAIDs received boxed warnings on their labels. Many COX-2–specific inhibitors have been removed from the US market. As of December 2011, only Celebrex (celecoxib) is still available for purc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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International Society For Pharmacoepidemiology
The International Society for Pharmacoepidemiology (ISPE) is a society focused on the practice of pharmacoepidemiology. The society was launched officially by Stanley A. Edlavitch, David E. Lilienfeld, and Hugh A. Tilson in 1989 during the Fifth International Conference on Pharmacoepidemiology (ICPE) in Minneapolis. ISPE is the only international acting society dealing with the topics of pharmacoepidemiology in the context of pharmacovigilance or drug safety; the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) addresses outcomes research epidemiology. The society has organized yearly conferences since its foundation. The society's office is located in Bethesda, Maryland, and its executive secretary is James Vrac. A number of the major figures in drug safety and pharmacovigilance have served as its Presidents, and its Officers and Trustees have been drawn from the leadership of the pharmacoepidemiology community. Members of the Society come from 53 natio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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The Daily Show
''The Daily Show'' is an American late-night talk show, late-night talk and news satire television program. It airs each Monday through Thursday on Comedy Central in the United States, with extended episodes released shortly after on Paramount+. ''The Daily Show'' draws its comedy and satire from recent news stories, political figures, and media organizations. It often uses self-referential humor. The half-hour-long show premiered on July 22, 1996, and was first hosted by Craig Kilborn until December 17, 1998. Jon Stewart then took over as the host from January 11, 1999, until August 6, 2015, making the show more strongly focused on political satire and news satire, in contrast with the pop culture focus during Kilborn's tenure. Stewart was succeeded by Trevor Noah, whose tenure began on September 28, 2015, and ended in December 2022. Under the different hosts, the show has been formally known as ''The Daily Show with Craig Kilborn'' from 1996 to 1998, ''The Daily Show with Jon ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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The Wall Street Journal
''The Wall Street Journal'' (''WSJ''), also referred to simply as the ''Journal,'' is an American newspaper based in New York City. The newspaper provides extensive coverage of news, especially business and finance. It operates on a subscription model, requiring readers to pay for access to most of its articles and content. The ''Journal'' is published six days a week by Dow Jones & Company, a division of News Corp. As of 2023, ''The'' ''Wall Street Journal'' is the List of newspapers in the United States, largest newspaper in the United States by print circulation, with 609,650 print subscribers. It has 3.17 million digital subscribers, the second-most in the nation after ''The New York Times''. The newspaper is one of the United States' Newspaper of record, newspapers of record. The first issue of the newspaper was published on July 8, 1889. The Editorial board at The Wall Street Journal, editorial page of the ''Journal'' is typically center-right in its positio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nova Scotia
Nova Scotia is a Provinces and territories of Canada, province of Canada, located on its east coast. It is one of the three Maritime Canada, Maritime provinces and Population of Canada by province and territory, most populous province in Atlantic Canada, with an estimated population of over 1 million as of 2024; it is also the second-most densely populated province in Canada, and second-smallest province by area. The province comprises the Nova Scotia peninsula and Cape Breton Island, as well as 3,800 other coastal islands. The province is connected to the rest of Canada by the Isthmus of Chignecto, on which the province's land border with New Brunswick is located. Nova Scotia's Capital city, capital and largest municipality is Halifax, Nova Scotia, Halifax, which is home to over 45% of the province's population as of the 2021 Canadian census, 2021 census. Halifax is the List of census metropolitan areas and agglomerations in Canada, twelfth-largest census metropolitan area in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Israel
Israel, officially the State of Israel, is a country in West Asia. It Borders of Israel, shares borders with Lebanon to the north, Syria to the north-east, Jordan to the east, Egypt to the south-west, and the Mediterranean Sea to the west. Israeli-occupied territories, It occupies the Occupied Palestinian territories, Palestinian territories of the West Bank in the east and the Gaza Strip in the south-west. Israel also has a small coastline on the Red Sea at its southernmost point, and part of the Dead Sea lies along its eastern border. Status of Jerusalem, Its proclaimed capital is Jerusalem, while Tel Aviv is the country's Gush Dan, largest urban area and Economy of Israel, economic center. Israel is located in a region known as the Land of Israel, synonymous with the Palestine (region), Palestine region, the Holy Land, and Canaan. In antiquity, it was home to the Canaanite civilisation followed by the History of ancient Israel and Judah, kingdoms of Israel and Judah. Situate ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Australia
Australia, officially the Commonwealth of Australia, is a country comprising mainland Australia, the mainland of the Australia (continent), Australian continent, the island of Tasmania and list of islands of Australia, numerous smaller islands. It has a total area of , making it the list of countries and dependencies by area, sixth-largest country in the world and the largest in Oceania. Australia is the world's flattest and driest inhabited continent. It is a megadiverse countries, megadiverse country, and its size gives it a wide variety of landscapes and Climate of Australia, climates including deserts of Australia, deserts in the Outback, interior and forests of Australia, tropical rainforests along the Eastern states of Australia, coast. The ancestors of Aboriginal Australians began arriving from south-east Asia 50,000 to 65,000 years ago, during the Last Glacial Period, last glacial period. By the time of British settlement, Aboriginal Australians spoke 250 distinct l ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Kentucky
Kentucky (, ), officially the Commonwealth of Kentucky, is a landlocked U.S. state, state in the Southeastern United States, Southeastern region of the United States. It borders Illinois, Indiana, and Ohio to the north, West Virginia to the northeast, Virginia to the east, Tennessee to the south, and Missouri to the west. Its northern border is defined by the Ohio River. Its capital is Frankfort, Kentucky, Frankfort and its List of cities in Kentucky, most populous city is Louisville, Kentucky, Louisville. As of 2024, the state's population was approximately 4.6 million. Previously part of Colony of Virginia, colonial Virginia, Kentucky was admitted into the Union as the fifteenth state on June 1, 1792. It is known as the "Bluegrass State" in reference to Kentucky bluegrass, a species of grass introduced by European settlers which has long supported the state's thoroughbred horse industry. The fertile soil in the central and western parts of the state led to the development ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |