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HOT-2
HOT-2 (2,5-dimethoxy-4-(β-ethylthio)-''N''-hydroxyphenethylamine) is a psychedelic phenethylamine of the 2C and HOT-x families. It was presumably first synthesized by Alexander Shulgin and reported in his book ''PiHKAL''. Chemistry HOT-2's full chemical name is 2- ethyl_group">ethyl<_a>Thio-.html" ;"title="ethyl_group.html" ;"title="-(2-ethyl group">ethylThio-">thio)-2,5-dimethoxyphenyl–Nitrogen, N–hydroxyl, hydroxyethanamine. It has structure, structural properties similar to 2C-T-2 and to other drugs in the HOT- series, with the most closely related compounds being HOT-7 and HOT-17. General information The dosage range of HOT-2 is typically 10-18 mg and its duration is approximately 6–10 hours according to Shulgin. HOT-2 produces visuals and moving, flowing lights. It also causes euphoria and increases blood pressure. Legality United Kingdom This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act. See also * Pheneth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HOT-x (psychedelics)
HOT-x, also known as 2,5-dimethoxy-4-(β-alkylthio)-''N''-hydroxyphenethylamines, are a group of psychedelic drugs of the substituted phenethylamine, phenethylamine and 2C (psychedelics), 2C families. They have a hydroxy group (HO) at the amine as well as methoxy groups at the 2 and 5 positions and an alkyl group, alkylthio-, thio (T) group at the 4 position of the phenyl ring. The HOT-x drugs are the ''N''-hydroxyl structural analog, analogues of the corresponding 2C-T-x drugs. They were chemical synthesis, synthesized and tested by Alexander Shulgin and reported in his 1991 book ''PiHKAL'' (''Phenethylamines I Have Known and Loved''). List of HOT-x drugs The HOT-x drugs include the following: * HOT-2 (2,5-dimethoxy-4-(β-ethylthio)-''N''-hydroxyphenethylamine) – the HOT-x analogue of 2C-T-2 * HOT-7 (2,5-dimethoxy-4-(β-propylthio)-''N''-hydroxyphenethylamine) – the HOT-x analogue of 2C-T-7 * HOT-17 (2,5-dimethoxy-4-(β-isobutylthio)-''N''-hydroxyphenethylamine) – the HOT-x ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PiHKAL
''PiHKAL: A Chemical Love Story'' is a book by Alexander Shulgin and Ann Shulgin published in 1991. The subject of the work is Psychoactive drug, psychoactive phenethylamine Derivative (chemistry), chemical derivatives, notably those that act as psychedelic drug, psychedelics and/or empathogen-entactogens. The main title, PiHKAL, is an acronym that stands for "Phenethylamines I Have Known and Loved". The book is arranged into two parts, the first part being a fictionalized autobiography of the couple and the second part describing 179 different psychedelic compounds (most of which Shulgin discovered himself), including detailed synthesis instructions, bioassays, dosages, and other commentary. The second part was made freely available by Shulgin on Erowid while the first part is available only in the printed text. While the reactions described are beyond the ability of people with a basic chemistry education, some tend to emphasize techniques that do not require difficult-to-ob ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HOT-17
HOT-17 (2,5-dimethoxy-4-(β-isobutylthio)-''N''-hydroxyphenethylamine) is a psychedelic phenethylamine of the 2C and HOT-x families. It was synthesized by Alexander Shulgin and reported in his book ''PiHKAL''. Chemistry HOT-17's full chemical name is 2- isobutyl">-(2-isobutyl<_a>Thio-.html" ;"title="isobutyl.html" ;"title="-(2-isobutyl">-(2-isobutylThio-">thio)-2,5-dimethoxyphenyl-Nitrogen, ''N''-hydroxyl, hydroxyethanamine. It has chemical structure, structural properties similar to 2C-T-17 and to other drugs in the HOT- series, with the most closely related compounds being HOT-2 and HOT-7. Use and effects The dosage range of HOT-17 is typically 70-120 mg and its duration is approximately 12–18 hours according to Shulgin. HOT-17 produces time distortion and general psychedelia. It also has little to no body load. See also * Phenethylamine Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a cent ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HOT-7
HOT-7, or 2,5-dimethoxy-4-(β-propylthio)-N-hydroxyphenethylamine, is a psychedelic drug, psychedelic phenethylamine of the 2C's, 2C and HOT-x (psychedelics), HOT-x families. It was presumably first synthesized by Alexander Shulgin and reported in his book, ''PiHKAL''. Chemistry HOT-7's full chemical name is 2-[4-(2-propylThio-, thio)-2,5-dimethoxyphenyl–Nitrogen, N–hydroxyl, hydroxyethanamine. It has structure, structural properties similar to 2C-T-7 and to other drugs in the HOT- series, with the most closely related compounds being HOT-2 and HOT-17. General information The dosage range of HOT-7 is typically 15-25 milligram, mg and its duration is approximately 6–8 hours according to Shulgin. HOT-7 produces closed-eye and open-eye visuals. It also induces a feeling similar to that of being drunk. Legality United Kingdom This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act#Class A drugs, Drugs controlled by the UK Misuse of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychedelic Drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic hallucinogens or serotonergic hallucinogens, the term ''psychedelic'' is sometimes used more broadly to include various other types of hallucinogens as well, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively. Classic psychedelics generally cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, LSD, psilocybin, and DMT. There are a large number of both naturally occurring and synthetic serotonergic psychedelics. Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hydroxyl
In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula and composed of one oxygen atom covalently bonded to one hydrogen atom. In organic chemistry, alcohols and carboxylic acids contain one or more hydroxy groups. Both the negatively charged anion , called hydroxide, and the neutral radical , known as the hydroxyl radical, consist of an unbonded hydroxy group. According to IUPAC definitions, the term ''hydroxyl'' refers to the hydroxyl radical () only, while the functional group is called a ''hydroxy group''. Properties Water, alcohols, carboxylic acids, and many other hydroxy-containing compounds can be readily deprotonated due to a large difference between the electronegativity of oxygen (3.5) and that of hydrogen (2.1). Hydroxy-containing compounds engage in intermolecular hydrogen bonding increasing the electrostatic attraction between molecules and thus to higher boiling and melting points than found for compounds that lack thi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drugs Controlled By The UK Misuse Of Drugs Act
The Misuse of Drugs Act 1971 (c. 38) is an act of the Parliament of the United Kingdom. It represents action in line with treaty commitments under the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances. Offences under the act include: * Possession of a controlled drug unlawfully * Possession of a controlled drug with intent to supply it * Supplying or offering to supply a controlled drug (even where no charge is made for the drug) * Allowing premises you occupy or manage to be used unlawfully for the purpose of producing or supplying controlled drugs The act establishes the Home Secretary as the principal authority in a drug licensing system. Therefore, for example, various opiates are available legally as prescription-only medicines, and cannabis (hemp) may be grown under licence for 'industrial purposes'. The ( SI 2001/3998), created under ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Milligram
The kilogram (also spelled kilogramme) is the base unit of mass in the International System of Units (SI), equal to one thousand grams. It has the unit symbol kg. The word "kilogram" is formed from the combination of the metric prefix kilo- (meaning one thousand) and gram; it is colloquially shortened to "kilo" (plural "kilos"). The kilogram is an SI base unit, defined ultimately in terms of three defining constants of the SI, namely a specific transition frequency of the caesium-133 atom, the speed of light, and the Planck constant. A properly equipped metrology laboratory can calibrate a mass measurement instrument such as a Kibble balance as a primary standard for the kilogram mass. The kilogram was originally defined in 1795 during the French Revolution as the mass of one litre of water (originally at 0 °C, later changed to the temperature of its maximum density, approximately 4 °C). The current definition of a kilogram agrees with this original defini ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C-T-2
2C-T-2, also known as 4-ethylthio-2,5-dimethoxyphenethylamine, is a psychedelic and entactogenic phenethylamine of the 2C family. It was first synthesized in 1981 by Alexander Shulgin, and rated by him as one of the "magical half-dozen" most important psychedelic phenethylamine compounds. The drug has structural and pharmacodynamic properties similar to those of 2C-T-7 ("Blue Mystic"). Dosage In Alexander Shulgin's book ''PiHKAL'', the dosage range is listed as 12 to 25 mg. Pharmacology The mechanism of action that produces 2C-T-2’s hallucinogenic and entheogenic effects is shown to be most likely a result from action as a 5-HT2A, 5-HT2B, and 5-HT2C serotonin receptor agonist, a mechanism of action shared by the hallucinogenic tryptamines and phenethylamines to varying degrees. 2C-T-2 has also shown to be a partial agonist of adrenergic receptors. Dangers A potential risk of neurotoxicity from 2C-T-2 use (and 2C chemical series in general) has been show ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Structure
A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as biological organisms, minerals and chemicals. Abstract structures include data structures in computer science and musical form. Types of structure include a hierarchy (a cascade of one-to-many relationships), a network featuring many-to-many links, or a lattice featuring connections between components that are neighbors in space. Load-bearing Buildings, aircraft, skeletons, anthills, beaver dams, bridges and salt domes are all examples of load-bearing structures. The results of construction are divided into buildings and non-building structures, and make up the infrastructure of a human society. Built structures are broadly divided by their varying design approaches and standards, into categories including building struct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenyl
In organic chemistry, the phenyl group, or phenyl ring, is a cyclic group of atoms with the formula , and is often represented by the symbol Ph (archaically φ) or Ø. The phenyl group is closely related to benzene and can be viewed as a benzene ring, minus a hydrogen atom, which may be replaced by some other element or compound to serve as a functional group. A phenyl group has six carbon atoms bonded together in a hexagonal planar ring, five of which are bonded to individual hydrogen atoms, with the remaining carbon bonded to a substituent. Phenyl groups are commonplace in organic chemistry. Although often depicted with alternating double and single bonds, the phenyl group is chemically aromatic and has equal bond lengths between carbon atoms in the ring. Nomenclature Usually, a "phenyl group" is synonymous with and is represented by the symbol Ph (archaically, Φ), or Ø. Benzene is sometimes denoted as PhH. Phenyl groups are generally attached to other atoms or groups. Fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nitrogen
Nitrogen is a chemical element; it has Symbol (chemistry), symbol N and atomic number 7. Nitrogen is a Nonmetal (chemistry), nonmetal and the lightest member of pnictogen, group 15 of the periodic table, often called the Pnictogen, pnictogens. It is a common element in the universe, estimated at Abundance of the chemical elements, seventh in total abundance in the Milky Way and the Solar System. At standard temperature and pressure, two atoms of the element chemical bond, bond to form N2, a colourless and odourless diatomic molecule, diatomic gas. N2 forms about 78% of Atmosphere of Earth, Earth's atmosphere, making it the most abundant chemical species in air. Because of the volatility of nitrogen compounds, nitrogen is relatively rare in the solid parts of the Earth. It was first discovered and isolated by Scottish physician Daniel Rutherford in 1772 and independently by Carl Wilhelm Scheele and Henry Cavendish at about the same time. The name was suggested by French chemist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
