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Epitestosterone
Epitestosterone, or isotestosterone, also known as 17α-testosterone or as androst-4-en-17α-ol-3-one, is an endogenous steroid and an epimer of the androgen sex hormone testosterone. It is a weak competitive antagonist of the androgen receptor (AR) and a potent 5α-reductase inhibitor. Structurally, epitestosterone differs from testosterone only in the configuration at the hydroxy-bearing carbon, C17. Epitestosterone is believed to form in a similar way to testosterone; a 1993 study found that around 50% of epitestosterone production in human males can be ascribed to the testis, although the exact pathway of its formation is still the subject of research. It has been shown to accumulate in mammary cyst fluid and in the prostate. Epitestosterone levels are typically highest in young males; however, by adulthood, most healthy males exhibit a testosterone to epitestosterone ratio (T/E ratio) of about 1:1. Society and culture Detection of athletic doping It has been shown that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doping (Sport)
In competitive sports, doping is the use of banned athletic performance-enhancing drugs (PEDs) by athletes, as a way of cheating. As stated in the World Anti-Doping Code by WADA, doping is defined as the occurrence of one or more of the anti-doping rule violations outlined in Article 2.1 through Article 2.11 of the Code. The term ''doping'' is widely used by organizations that regulate sporting competitions. The use of drugs to enhance performance is considered unethical and is prohibited by most international sports organizations, including the International Olympic Committee. Furthermore, athletes (or athletic programs) taking explicit measures to evade detection exacerbate the ethical violation with overt deception and cheating. The origins of doping in sports go back to the creation of the sport itself. From ancient usage of substances in chariot racing to more recent controversies in doping in baseball, doping in tennis, doping at the Olympic Games, and doping at the T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mary Decker
Mary Teresa Slaney (formerly Tabb, Married and maiden names, née Decker, born August 4, 1958) is an American retired middle-distance and long-distance runner. During her career, she won gold medals in the 1500 metres, 1500 meters and 3000 metres, 3000 meters at the 1983 World Championships in Athletics, 1983 World Championships and was the world-record holder in the mile run, mile, 5000 metres, 5000 meters and 10,000 metres, 10,000 meters. In total, she set 17 official and unofficial List of world records in athletics, world records, and she was the first woman to break 4:20 for mile run world record progression, the mile. She also set 36 United States records in track and field, U.S. national records at distances ranging from 800 meters to 10,000 meters, and has held the U.S. record in the 2000 meters and 3000 meters since the early 1980s, while her 1500 meters record stood for 32 years and her mile record stood for 38 years. In 2003, she was inducted into the National Track an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2006 Tour De France
The 2006 Tour de France was the 93rd edition of the Tour de France, one of cycling's Grand Tour (cycling), Grand Tours. It took place between the 1st and the 23rd of July. It was won by Óscar Pereiro following the disqualification of Floyd Landis. Due to the United States Anti-Doping Agency announcing on August 24, 2012, that they had disqualified Lance Armstrong, a former teammate of Landis, from all of his results since August 1, 1998, including his seven Tour de France titles from 1999 to 2005, this is also the first Tour to have an overall winner since 1998. By terms of margin of victory the 2006 Tour was the Tour de France records and statistics#Smallest winning margin, 3rd closest of all time. The Tour began with a prologue in Strasbourg, on the French-German border, and ended on Sunday 23 July in Paris. The distance of the course (run counterclockwise around France) was . The race was the third fastest in average speed. Along the way, the cyclists passed through six diffe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Floyd Landis
Floyd Landis (born October 14, 1975) is an American former professional road racing cyclist. At the 2006 Tour de France, he would have been the third non-European winner in the event's history, but was disqualified after testing positive for performance-enhancing drugs. The competition was ultimately won by Óscar Pereiro. Landis was an all-around rider, with special skills in climbing, time-trialing, and descending. He turned professional in 1999 with the Mercury Cycling Team, joined the U.S. Postal Service team in 2002, and moved to the Phonak Hearing Systems team in 2005. In January 2010, a French judge issued a national arrest warrant for Landis on computer hacking charges related to the 2006 Tour de France, stage 17 doping allegations. In 2010 Landis maintained his innocence and mounted a defense. Although his legal team documented inconsistencies in the handling and evaluation of his urine samples, the disqualification was upheld. He was suspended from professional ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Testosterone (medication)
Testosterone is a medication and naturally occurring testosterone, steroid hormone. It is used to treat male hypogonadism, gender dysphoria, and certain types of breast cancer. It may also be used to increase athletic ability in the form of doping in sport, doping. It is unclear if the use of testosterone for andropause, low levels due to aging is beneficial or harmful. Testosterone can be administered through several different routes, including Topical medication, topical gels or transdermal patch, patches, nasal sprays, subdermal implants, or Buccal administration, tablets dissolved inside the mouth. Testosterone therapy has been associated with improvements in Depression (mood), depressive symptoms (especially in Hypogonadism, hypogonadal men), increased exercise capacity and muscle strength in men with Heart failure, chronic heart failure, and Male contraceptive, male contraception effectiveness. Common side effects of testosterone include acne, swelling (medical), swel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1980 Summer Olympics
The 1980 Summer Olympics (), officially known as the Games of the XXII Olympiad () and officially branded as Moscow 1980 (), were an international multi-sport event held from 19 July to 3 August 1980 in Moscow, Soviet Union, in present-day Russia. The games were the first to be staged in an Eastern Bloc country, as well as the first Olympic Games and only Summer Olympics to be held in a Slavic languages, Slavic language-speaking country. They were also the only Summer Olympic Games to be held in a self-proclaimed communist country until the 2008 Summer Olympics held in China. These were the final Olympic Games under the International Olympic Committee, IOC Presidency of Michael Morris, 3rd Baron Killanin before he was succeeded by Juan Antonio Samaranch shortly afterward. Eighty nations were represented at the Moscow Games, the smallest number since 1956 Summer Olympics, 1956. Led by the United States, 66 countries 1980 Summer Olympics boycott, boycotted the games entirely, beca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Australian Senate
The Senate is the upper house of the Bicameralism, bicameral Parliament of Australia, the lower house being the Australian House of Representatives, House of Representatives. The powers, role and composition of the Senate are set out in Chapter I of the Constitution of Australia, federal constitution as well as federal legislation and Constitutional convention (political custom), constitutional convention. There are a total of 76 senators: twelve are elected from each of the six states and territories of Australia, Australian states, regardless of population, and two each representing the Australian Capital Territory (including the Jervis Bay Territory and Norfolk Island) and the Northern Territory (including the Australian Indian Ocean Territories). Senators are popularly elected under the single transferable vote system of proportional representation in state-wide and territory-wide districts. Section 24 of the Constitution of Australia, Section 24 of the Constitution provi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Androstanes
An androgen (from Greek ''andr-'', the stem of the word meaning ) is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes the embryological development of the primary male sex organs, and the development of male secondary sex characteristics at puberty. Androgens are synthesized in the testes, the ovaries, and the adrenal glands. Androgens increase in both males and females during puberty. The major androgen in males is testosterone. Dihydrotestosterone (DHT) and androstenedione are of equal importance in male development. DHT ''in utero'' causes differentiation of the penis, scrotum and prostate. In adulthood, DHT contributes to balding, prostate growth, and sebaceous gland activity. Although androgens are commonly thought of only as male sex hormones, females also have them, but at lower levels: they function in libido and sexual arousal. Andro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ESPN
ESPN (an initialism of their original name, which was the Entertainment and Sports Programming Network) is an American international basic cable sports channel owned by the Walt Disney Company (80% and operational control) and Hearst Communications (20%) through the joint venture ESPN Inc. The company was founded in 1979 by Bill Rasmussen, Scott Rasmussen and Ed Eagan. ESPN broadcasts primarily from studio facilities located in Bristol, Connecticut. The network also operates offices and auxiliary studios in Miami, Orlando, New York City, Las Vegas, Seattle, Charlotte, Washington, D.C., and Los Angeles. James Pitaro has been chairman since March 5, 2018, following the resignation of John Skipper on December 18, 2017. , ESPN is available to approximately 70 million pay television households in the United States—down from its 2011 peak of 100 million households. It operates regional channels in Africa, Australia, Latin America, and the Netherlands. In Ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isotope-ratio Mass Spectrometry
Isotope-ratio mass spectrometry (IRMS) is a specialization of mass spectrometry, in which mass spectrometric methods are used to measure the relative abundance of isotopes in a given sample. This technique has two different applications in the earth and environmental sciences. The analysis of ' stable isotopes' is normally concerned with measuring isotopic variations arising from mass-dependent isotopic fractionation in natural systems. On the other hand, radiogenic isotope analysis involves measuring the abundances of decay-products of natural radioactivity, and is used in most long-lived radiometric dating methods. Introduction The isotope-ratio mass spectrometer (IRMS) allows the precise measurement of mixtures of naturally occurring isotopes. Most instruments used for precise determination of isotope ratios are of the magnetic sector type. This type of analyzer is superior to the quadrupole type in this field of research for two reasons. First, it can be set up for multip ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
