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DOM-AI
DOM-AI, also known as 4,7-dimethoxy-5-methyl-2-aminoindane, is a putative serotonergic psychedelic of the 2-aminoindane group related to DOM. It is a cyclized phenethylamine and the cyclized 2-aminoindane analogue of DOM. The drug fully substituted for LSD in rodent drug discrimination tests, suggesting that it may have hallucinogenic effects in humans. However, DOM-AI was much less potent than DOM in these tests, with an of 2.18mg/kg, which was approximately 1/15th that of DOM. Nonetheless, DOM-AI is still active in showing psychedelic-like effects in animals, in contrast to its analogues DOM-AT and DOM-CR. DOM-AI was first described in the scientific literature by David E. Nichols and colleagues in 1974. Other cyclized analogues of DOM and related psychedelics besides DOM-AI, DOM-AT, and DOM-CR include DMCPA, TFMBOX, jimscaline, TCB-2 TCB-2 is a hallucinogen discovered in 2006 by Thomas McLean working in the lab of David Nichols at Purdue University. It is a co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DOM-AT
DOM-AT, or DOMAT, also known as 5,8-dimethoxy-6-methyl-2-aminotetralin, is a cyclized phenethylamine and 2-aminotetralin related to the psychedelic substituted amphetamine, amphetamine DOM (drug), DOM. It is specifically the cyclized 2-aminotetralin structural analog, analogue of DOM. The compound has been found to be a more potency (pharmacology), potent agonist of human body, peripheral serotonin receptors than DOM ''in vitro''. This activity was blocked by the serotonin receptor antagonist cinanserin and by the non-hallucinogenic serotonin receptor modulator 2-bromo-LSD (BOL-148). However, DOM-AT was not tested for hallucinogen-type activity in animals or humans in these studies. Subsequently, DOM-AT did not appear to show a typical hallucinogen-like profile in behavioral tests in rats (e.g., the conditioned avoidance response test). In cats, DOM-AT produced a rage reaction, while in rabbits, it produced stimulant, behavioral excitation and hyperthermia. In later research, DOM- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |