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Bio-MEMS
Bio-MEMS is an abbreviation for biomedical (or biological) microelectromechanical systems. Bio-MEMS have considerable overlap, and is sometimes considered synonymous, with lab-on-a-chip (LOC) and micro total analysis systems (μTAS). Bio-MEMS is typically more focused on mechanical parts and microfabrication technologies made suitable for biological applications. On the other hand, lab-on-a-chip is concerned with miniaturization and integration of laboratory processes and experiments into single (often microfluidic) chips. In this definition, lab-on-a-chip devices do not strictly have biological applications, although most do or are amenable to be adapted for biological purposes. Similarly, micro total analysis systems may not have biological applications in mind, and are usually dedicated to chemical analysis. A broad definition for bio-MEMS can be used to refer to the science and technology of operating at the microscale for biological and biomedical applications, which may or m ...
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Microelectromechanical Systems
Microelectromechanical systems (MEMS), also written as micro-electro-mechanical systems (or microelectronic and microelectromechanical systems) and the related micromechatronics and microsystems constitute the technology of microscopic devices, particularly those with moving parts. They merge at the nanoscale into nanoelectromechanical systems (NEMS) and nanotechnology. MEMS are also referred to as micromachines in Japan and microsystem technology (MST) in Europe. MEMS are made up of components between 1 and 100 micrometers in size (i.e., 0.001 to 0.1 mm), and MEMS devices generally range in size from 20 micrometres to a millimetre (i.e., 0.02 to 1.0 mm), although components arranged in arrays (e.g., digital micromirror devices) can be more than 1000 mm2. They usually consist of a central unit that processes data (an integrated circuit chip such as microprocessor) and several components that interact with the surroundings (such as microsensors). Because of the ...
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Total Analysis System
Total Analysis System (TAS) describes a device that automates and includes all necessary steps for chemical analysis of a sample e.g. sampling, sample transport, filtration, dilution, chemical reactions, separation and detection. µTAS A new trend today is creating Micro Total Analysis Systems - µTAS. Such a system shall shrink a whole laboratory to chip-size lab-on-a-chip. Because of its very small size, such a system can be placed close to a sampling site. It also can be very cost effective thinking of chip technologies, sample sizes and analysis time. It also reduces the exposure of the toxic chemical on the lab personnel which is an added advantage than the conventional techniques. Another advantage of this technology is that the point-of-use diagnostic kits which do not require skilled technicians during the epidemical events and thus help to save millions of lives. See also * Microelectromechanical systems *Microfluidics *Bio-MEMS *Lab-on-a-Chip A lab-on-a-chip ...
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in gen ...
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Fertility Monitor
Fertility testing is the process by which fertility is assessed, both generally and also to find the "fertile window" in the menstrual cycle. General health affects fertility, and STI testing is an important related field. Women Healthy women are fertile from puberty until menopause, although fertility is typically much reduced towards the extremes of this period. The onset of puberty is typically identified by menarche and the presence of secondary sexual characteristics such as breast development, the appearance of pubic hair and changes to body fat distribution. The end of fertility typically comes somewhat before menopause, as fertility declines to a point where establishing a viable pregnancy is very unlikely. Ovulation testing Various methods of predicting the timing of ovulation exist, some of which may be performed at home or in a clinical setting. Knowing the timing of ovulation can help a woman to determine the days of the menstrual cycle that are most likely to re ...
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Clearblue
Clearblue is a brand of Swiss Precision Diagnostics that offers consumer home diagnostic products such as pregnancy tests, ovulation tests and fertility monitors. Product history Clearblue was introduced in 1985 with the launch of the first Clearblue Home Pregnancy Test system, which at the time was owned by Unilever. It was the world’s first “rapid home test” that gave pregnancy test results in 30 minutes and allowed a woman to take a test before going to the doctor. The test was a three-step process using a dipstick and small tray. In 1988, Clearblue launched the first one-step pregnancy test with the invention of lateral flow technology. This one-step test gave a result in 3 minutes, subsequently reduced to a 1-minute result when Clearblue introduced the world’s first one-minute home pregnancy test in 1996. In 2003, Clearblue released the first digital pregnancy test to show the result in words ‘Pregnant’ or ‘Not Pregnant’ on a digital screen. In 2008, ...
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Unipath
Unipath Ltd was a pharmaceutical company, subsidiary to Unilever and then Alere, specialising mainly in medical diagnostic kits related to women's reproductive health. It subsequently diversified its product range to include more specialised test kits, primarily for the clinical market, in areas other than women's reproductive healthcare. Based in Bedford, United Kingdom, the company had between 500 and 600 employees globally. Unipath's main assets were folded into Swiss Precision Diagnostics. History Unipath was formed in 1984 by the Unilever group. In 1985 they released and started to manufacture the first in their line of home pregnancy test kits marketed under the Clearblue brand. The name is related to the fact that the test produced a blue marker line as a positive (pregnant) result and that it is 'clear' and simple to use. The product was a success, in part due to intensive advertising and held a majority market share in the UK by the end of the year. Unipath released ...
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Cell Adhesion
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released by cells into spaces between them. Cells adhesion occurs from the interactions between cell-adhesion molecules (CAMs), transmembrane proteins located on the cell surface. Cell adhesion links cells in different ways and can be involved in signal transduction for cells to detect and respond to changes in the surroundings. Other cellular processes regulated by cell adhesion include cell migration and tissue development in multicellular organisms. Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. Cell adhesion is also essential for in ...
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Palladium
Palladium is a chemical element with the symbol Pd and atomic number 46. It is a rare and lustrous silvery-white metal discovered in 1803 by the English chemist William Hyde Wollaston. He named it after the asteroid Pallas, which was itself named after the epithet of the Greek goddess Athena, acquired by her when she slew Pallas. Palladium, platinum, rhodium, ruthenium, iridium and osmium form a group of elements referred to as the platinum group metals (PGMs). They have similar chemical properties, but palladium has the lowest melting point and is the least dense of them. More than half the supply of palladium and its congener platinum is used in catalytic converters, which convert as much as 90% of the harmful gases in automobile exhaust ( hydrocarbons, carbon monoxide, and nitrogen dioxide) into nontoxic substances ( nitrogen, carbon dioxide and water vapor). Palladium is also used in electronics, dentistry, medicine, hydrogen purification, chemical applic ...
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Andreas Manz 0185 - MicroTAS 2007
Andreas ( el, Ἀνδρέας) is a name usually given to males in Austria, Greece, Cyprus, Denmark, Armenia, Estonia, Ethiopia, Eritrea, Finland, Flanders, Germany, Norway, Sweden, Switzerland, Romania, the Netherlands, and Indonesia. The name derives from the Greek noun ἀνήρ ''anēr'', with genitive ἀνδρός ''andros'', which means "man". See the article on ''Andrew'' for more information. The Scandinavian name is earliest attested as antreos in a runestone from the 12th century. The name Andrea may be used as a feminine form, but is instead the main masculine form in Italy and the canton of Ticino in Switzerland. Given name Andreas is a common name, and this is not a comprehensive list of articles on people named Andreas. See instead . Surname * Alfred T. Andreas, American publisher and historian * Casper Andreas (born 1972), American actor and film director * Dwayne Andreas, a businessman * Harry Andreas * Lisa Andreas Places *Andreas, Isle of Man, a village a ...
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Venn Diagram For BioMEMS, LOC, And MTAS
Venn is a surname and a given name. It may refer to: Given name * Venn Eyre (died 1777), Archdeacon of Carlisle, Cumbria, England * Venn Pilcher (1879–1961), Anglican bishop, writer, and translator of hymns * Venn Young (1929–1993), New Zealand politician Surname * Albert Venn (1867–1908), American lacrosse player * Anne Venn (1620s–1654), English religious radical and diarist * Blair Venn, Australian actor * Charles Venn (born 1973), British actor * Harry Venn (1844–1908), Australian politician * Henry Venn (Church Missionary Society) the younger (1796-1873), secretary of the Church Missionary Society, grandson of Henry Venn * Henry Venn (Clapham Sect) the elder (1725–1797), English evangelical minister * Horace Venn (1892–1953), English cricketer * John Venn (1834–1923), British logician and the inventor of Venn diagrams, son of Henry Venn the younger * John Venn (academic) (died 1687), English academic administrator * John Venn (politician) (1586–1650), Engl ...
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Single Cell Analysis
In the field of cellular biology, single-cell analysis is the study of genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level. The concept of single-cell analysis originated in the 1970s. Before the discovery of heterogeneity, single-cell analysis mainly referred to the analysis or manipulation of an individual cell in a bulk population of cells at a particular condition using optical or electronic microscope. To date, due to the heterogeneity seen in both eukaryotic and prokaryotic cell populations, analyzing a single cell makes it possible to discover mechanisms not seen when studying a bulk population of cells. Technologies such as fluorescence-activated cell sorting (FACS) allow the precise isolation of selected single cells from complex samples, while high throughput single cell partitioning technologies, enable the simultaneous molecular analysis of hundreds or thousands of single unsorted cells; this is partic ...
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