Zeng Rong () is a Chinese

biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...

researching and developing technology for

proteomics Proteomics is the large-scale study of proteins. Proteins are vital macromolecules of all living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replicatio ...

research. She is currently a professor at the Institute of Biochemistry and Cell Biology at the

Shanghai Institutes for Biological Sciences The Shanghai Institutes for Biological Sciences were research institutes of the Chinese Academy of Sciences in Shanghai Shanghai, Shanghainese: , Standard Chinese pronunciation: is a direct-administered municipality and the most populous u ...

Education

Zeng graduated from the Biology department at

Hunan Normal University Hunan Normal University (HunNU) is a provincial public university in Changsha, Hunan, China. It is affiliated with the Province of Hunan, and co-funded by the Hunan Provincial People's Government and the Ministry of Education. The university ...

in China in 1995, with a Bachelor's degree. She then got her doctoral degree in biochemistry and molecular biology in 2000, at the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences,

Chinese Academy of Sciences The Chinese Academy of Sciences (CAS; ) is the national academy for natural sciences and the highest consultancy for science and technology of the People's Republic of China. It is the world's largest research organization, with 106 research i ...

. She was mentored by a famous protein analyst Xia Qichang.

Career

Zeng has been working at the Institute of Biochemistry and Cell Biology where she got her doctoral degree since 2000 after her graduation. She works as a doctoral supervisor, and she is also the principal investigator of her research group. She was offered to be an editor of the magazine ''

Proteomics Proteomics is the large-scale study of proteins. Proteins are vital macromolecules of all living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replicatio ...

'' in January 2005, and ''Molecular and Cell Proteomics'' in 2006. Zeng was also accepted as a committee member of

HUPO The Human Proteome Organization (HUPO) is an international consortium of national proteomics research associations, government researchers, academic institutions, and industry partners. The organization was launched in February 2001, and it promotes ...

in September 2009. She has received honors and awards including the National Science Fund in 2004 and the Chinese Young Women in Science Fellowship Award in 2005.

Research focus

Zeng's main focus is on proteomics and the dynamic behavior of proteins. She leads a research team at the Institute of Biochemistry and Cell Biology at the Shanghai Institute for Biological Sciences to make progress in methodology development, application of quantitative proteomics, and regulation mechanism of protein dynamic behavior. Her team developed novel methods for proteomics research including multi-dimensional LC-MS/MS that can aid protein profiling, phosphopeptide enrichment, and multiplex quantitation. They applied quantitative proteomics in

cell signaling In biology, cell signaling (cell signalling in British English) is the Biological process, process by which a Cell (biology), cell interacts with itself, other cells, and the environment. Cell signaling is a fundamental property of all Cell (biol ...

and biomarker discovery of diabetes. Their work on proteins in and around cancer cells in human liver achieved better understanding of liver cancer. In order to regulate the mechanisms involved in the dynamic behavior of proteins, Zeng and her team utilized

epigenetic In biology, epigenetics is the study of changes in gene expression that happen without changes to the DNA sequence. The Greek prefix ''epi-'' (ἐπι- "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in ...

, transcriptomic, and

MiRNA Micro ribonucleic acid (microRNA, miRNA, μRNA) are small, single-stranded, non-coding RNA molecules containing 21–23 nucleotides. Found in plants, animals, and even some viruses, miRNAs are involved in RNA silencing and post-transcri ...

data along with proteomic data to find out how biological molecules interact on a systematic level.

Contributions to science

Zeng has published multiple papers in journals including but not limited to ''

Electrophoresis Electrophoresis is the motion of charged dispersed particles or dissolved charged molecules relative to a fluid under the influence of a spatially uniform electric field. As a rule, these are zwitterions with a positive or negative net ch ...

'', ''

Nature Nature is an inherent character or constitution, particularly of the Ecosphere (planetary), ecosphere or the universe as a whole. In this general sense nature refers to the Scientific law, laws, elements and phenomenon, phenomena of the physic ...

'', ''

Science Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which stu ...

'', ''

BMC Genomics ''BMC Genomics'' is an open-access scientific journal covering all areas of genomics and proteomics. The journal was established in 2000 and is published by BioMed Central. Its 2022 impact factor is 4.4. Abstracting and Indexing The journal is ...

'', ''

Journal of Proteome Research The ''Journal of Proteome Research'' is a peer-reviewed scientific journal published since 2002 by the American Chemical Society. Its publication frequency switched from bimonthly to monthly in 2006. The current editor-in-chief is John R. Yates. ...

,'' the ''Journal of Molecular Cell Biology'', and '' Molecular & Cellular Proteomics''. Some selected work listed below: * . The experimental result was used to help vaccine-related application. * . Her studies in the large scale proteome profiling was cited to bring up topics on related potential clinical applications. * . The team's discovery helped developing the idea about the conservation of certain mechanisms from bacteria to human. * . Figures from this paper was referred to as a confirmation to experimental results from similar researches done by other scientists.

References

External links

Official site
{{DEFAULTSORT:Zeng, Rong Chinese women chemists Chinese biochemists Living people 21st-century Chinese women scientists Year of birth missing (living people) Chinese women biologists Women biochemists Hunan Normal University alumni