Werner Ingold
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Werner Ingold (20 February 1919 – 24 June 1995) was a Swiss chemist and entrepreneur. He was a pioneer in the field of chemical microanalysis, in particular in the development of glass-based, highly resistive pH electrodes. In 1948, he founded the Dr. W. Ingold AG, producing and selling sensors for process analytical applications. He developed the company to a mid-size international business organization and sold it in 1986 to
Ciba Geigy Novartis AG is a Swiss multinational pharmaceutical corporation based in Basel, Switzerland. Novartis is one of the largest pharmaceutical companies in the world and was the eighth largest by revenue in 2024. Novartis manufactures the drugs c ...
. In 1966, Werner Ingold became an Active Life Member of The New York Academy of Sciences.


Early life and education

Werner Ingold was born on 20 February 1919 in Lüterkofen, in the rural area of
Solothurn Solothurn ( ; ; ; ; ) is a town, a municipality, and the capital of the canton of Solothurn in Switzerland. It is located in the north-west of Switzerland on the banks of the Aare and on the foot of the Weissenstein Jura mountains. The town is ...
, Switzerland. He was the youngest of three sons of Hans and Ida Ingold (née Santschi) to grow up on his father's farm. Werner attended primary and district school in the neighboring village of
Hessigkofen Hessigkofen is a former Municipalities of Switzerland, municipality in the Bucheggberg (district), district of Bucheggberg, in the canton of Solothurn, Switzerland. On 1 January 2014 the former municipalities of Hessigkofen, Tscheppach, Brügglen, ...
and grammar school at
Kantonsschule Solothurn The Kantonsschule Solothurn is a Gymnasium (school), gymnasium in the municipality of Solothurn, Switzerland. With approximately 1,800 students (stand: 2007) it is among the biggest schools in Switzerland. The current principal is Stefan Zumbrunn ...
.


Academic career

Between 1938 and 1942, Werner Ingold studied chemistry at the
Swiss Federal Institute of Technology The Swiss Federal Institutes of Technology are two institutes of higher education in Switzerland (part of the ETH Domain): * Swiss Federal Institute of Technology in Lausanne Swiss most commonly refers to: * the adjectival form of Switzerland *Sw ...
(ETH) in Zurich and obtained his diploma as a chemical engineer under Hans Eduard Fierz with his thesis "On the Constitution of Naphtaline-Yellow". He then earned his doctorate at the Institute of Organic Technology under
Leopold Ružička Leopold Ružička (; born Lavoslav Stjepan Ružička; 13 September 1887 – 26 September 1976) was a Croatian-Swiss scientist and joint winner of the 1939 Nobel Prize in Chemistry "for his work on polymethylenes and higher terpenes" "including ...
in the field of organic microanalysis of triterpene chemistry, completing his PhD in 1945 with the thesis "On Understanding Oleanolacid, Glycyrrhetinacid and Boswellinacid". After his dissertation, he remained at the Institute of Organic Technology at ETH, supported by a scholarship from the Foundation for the Promotion of Young Academics, and continued his research in the field of organic microanalysis. During his post-graduate studies, Werner Ingold applied glass electrodes for the
titration Titration (also known as titrimetry and volumetric analysis) is a common laboratory method of Quantitative research, quantitative Analytical chemistry, chemical analysis to determine the concentration of an identified analyte (a substance to be ...
of organic compounds. Glass electrodes were already known to be suitable for measuring acidity (pH) at that time. (Elaborating on scientific groundwork by Max Cremer (1906), Fritz Haber and Zygmunt Klemensievicz (1909), Dungan Macinnes and Malcom Dole had developed pH-sensitive glass electrodes at the Rockefeller Institute for Medical Research in New York.) However, the tips of these electrodes were very brittle. The inventors estimated the wall thickness of the membrane to be less than 0.001 mm. Furthermore, these electrodes were largely unavailable in Europe during
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
and therefore had to be manufactured in chemical laboratories. During this time, Werner Ingold acquired a profound knowledge on glass and its manufacturing that allowed him to produce more robust pH electrodes that were suitable for laboratory and industrial applications. Werner Ingold was personally dedicated to the development and improvement of glasses for pH measurement until the sale of his company.


Company foundation and development

In 1948, Werner Ingold started to produce glass electrodes for pH measurement, initially as a one-man company operating out of Huttenstrasse 24 in
Zurich Zurich (; ) is the list of cities in Switzerland, largest city in Switzerland and the capital of the canton of Zurich. It is in north-central Switzerland, at the northwestern tip of Lake Zurich. , the municipality had 448,664 inhabitants. The ...
. Before he devoted himself entirely to the commercialization of pH electrodes, he was contacted by the
Imperial Chemical Industries Imperial Chemical Industries (ICI) was a British Chemical industry, chemical company. It was, for much of its history, the largest manufacturer in Britain. Its headquarters were at Millbank in London. ICI was listed on the London Stock Exchange ...
(ICI) Plastics Division to establish a micro-analytical laboratory in
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,
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, UK.W. Ingold, Dechema-Monographien 43, 153/60 (1961): "pH-Messgeber für Drücke bis 25 atü und Temperaturen über 100°C" From 1950 onwards, Ingold advanced the manufacturing scale-up of pH sensors in Zurich. In 1952, the first employees joined the company and in the same year he founded Dr. W. Ingold GmbH in
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, Germany (converted into Dr. W. Ingold KG in 1960). In 1954, he converted the Zurich sole proprietorship into a stock corporation, Dr. W. Ingold AG.Interview in Swiss Chem 6 (1984) No. 8a, 68-76 "Dr. W. Ingold AG, CH-8903 Urdorf-Zurich – pH-Messtechnik 3x10 Jahre Ingold, Qualität feiert Jubiläum" In the early 1950s, the invention of the single-rod measuring cell, a combination of measurement and
reference electrode A reference electrode is an electrode that has a stable and well-known electrode potential. The overall chemical reaction taking place in a cell is made up of two independent half-reactions, which describe chemical changes at the two electrodes. ...
in one construction unit, marked a decisive step towards becoming one of the world's leading companies in the field of pH measurement. Ingold recognized early on the demand for high quality and robust pH electrodes in the biotech industry – e.g. for the production of
penicillin Penicillins (P, PCN or PEN) are a group of beta-lactam antibiotic, β-lactam antibiotics originally obtained from ''Penicillium'' Mold (fungus), moulds, principally ''Penicillium chrysogenum, P. chrysogenum'' and ''Penicillium rubens, P. ru ...
, where all sensors and fittings have to be sterilized at high temperatures and pressures. Therefore, in further development of pH electrodes, much emphasis was given on robustness and responsiveness of the sensors in harsh environments. Subsequently, the brands Argenthal (for high temperature, high pressure applications), EQUITHAL (compensates for temperature differences) and Xerolyt (without pressure compensation) were launched. Robust pH electrodes were also used in the chemical industry, and micro, puncture and surface electrodes were developed and commercialized for food applications. By 1955, the company developed fittings for the introduction of sensors into tank and piping systems, enabling in-line use of sensors for industrial applications. In the 1970s and 1980s, sensors for the measurement of liquefied oxygen and carbon dioxide, as well as ion-selective electrodes (such as, for ammonium and nitrate) were developed on the basis of the glass electrode technology.E. Puhar, A. Einsele, H. Bühler und W. Ingold, "Steam-Sterilisable pCO2-Electrode", Biotech. Bioeng. 22 (1980) 2411-2415. To complete the product range, measurement electronics produced by third-party suppliers were also sold. The production site in Zurich moved several times (in 1956 from Huttenstrasse 24 to Pfluggasse 6 and in 1961 to Scheuchzerstrasse 71). Finally, in 1974, the company built and moved into its own production site in
Urdorf Urdorf is a Municipalities of Switzerland, municipality in the district of Dietikon (district), Dietikon in the Cantons of Switzerland, canton of Zurich (canton), Zürich in Switzerland, located in the Limmat Valley (German: ''Limmattal''). Geogr ...
near Zurich. In 1966, together with Thomas A. Rosse of Instrumentation Laboratory Inc., Werner Ingold founded the joint-venture Ingold Electrode Inc. in Andover, Massachusetts (USA), for the production and distribution of sensors in North America. In 1970, the Ingold Technique sales and service branch was opened in
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, and in 1978, the Ingold Industria e Commercio Ltda. production facility in
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, Brazil. Werner Ingold, as Head of Technology, Chairman of the Board of Directors and the Executive Board, was responsible for product innovation and developing the group's expanding portfolio, Dr. René Baumann, as Head of Sales, Member of the Board of Directors and Member of the Executive Board, was in charge of commercial development and the build-up of the sales network. The Board of Directors was completed by Dr. Hans Huessy. By the mid-1980s, the group of companies employed approximately 200 professionals and supplied customers in 44 countries. In 1986, Ingold sold the company to Mettler Instruments AG, who at that time was owned by
Ciba Geigy Novartis AG is a Swiss multinational pharmaceutical corporation based in Basel, Switzerland. Novartis is one of the largest pharmaceutical companies in the world and was the eighth largest by revenue in 2024. Novartis manufactures the drugs c ...
. Today (2019), PO Ingold is a still prosperous business unit of Mettler-Toledo International.


Personal life and death

Werner Ingold married Irene Ingold (née Martin) in 1962 and had three children. The family moved from Zurich to Uitikon-Waldegg in 1969. After selling Ingold AG, Werner Ingold acquired the hotel Haus Paradies in
Ftan Ftan is a former municipality in the district of Inn in the Swiss canton of Graubünden. On 1 January 2015 the former municipalities of Ardez, Guarda, Tarasp, Ftan and Sent merged into the municipality of Scuol.1919 births 1995 deaths 20th-century Swiss chemists People from Solothurn ETH Zurich alumni Swiss company founders