Wendell Stanley
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Wendell Meredith Stanley (August 16, 1904June 15, 1971) was an American
biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...
, virologist and
Nobel laureate The Nobel Prizes (, ) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make outstanding contributions in th ...
.


Biography

Stanley was born in Ridgeville, Indiana, and earned a BSc in chemistry at Earlham College in
Richmond, Indiana Richmond () is a city in eastern Wayne County, Indiana, United States. Bordering the state of Ohio, it is the county seat of Wayne County. In the 2020 United States census, 2020 census, the city had a population of 35,720. It is the principal c ...
. He then studied at the
University of Illinois The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public university, public land-grant university, land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United ...
, gaining an MS in science in 1927 followed by a PhD in chemistry two years later. His later accomplishments include writing the book "Chemistry: A Beautiful Thing" and being a
Pulitzer Prize The Pulitzer Prizes () are 23 annual awards given by Columbia University in New York City for achievements in the United States in "journalism, arts and letters". They were established in 1917 by the will of Joseph Pulitzer, who had made his fo ...
nominee.


Research

Although a member of National Research Council, he moved to
Munich Munich is the capital and most populous city of Bavaria, Germany. As of 30 November 2024, its population was 1,604,384, making it the third-largest city in Germany after Berlin and Hamburg. Munich is the largest city in Germany that is no ...
for temporary academic work with Heinrich Wieland before he returned to the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
in 1931. On return he was approved as an assistant at The Rockefeller Institute for Medical Research. He remained with the Institute until 1948, becoming an Associate Member in 1937, and a Member in 1940. In 1948, he became Professor of Biochemistry at the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a Public university, public Land-grant university, land-grant research university in Berkeley, California, United States. Founded in 1868 and named after t ...
and built the Virus Laboratory and a free-standing Department of Biochemistry building, which is now called Stanley Hall. Stanley's work contributed to on lepracidal compounds, diphenyl
stereochemistry Stereochemistry, a subdiscipline of chemistry, studies the spatial arrangement of atoms that form the structure of molecules and their manipulation. The study of stereochemistry focuses on the relationships between stereoisomers, which are defined ...
and the chemistry of the sterols. His research on the
virus A virus is a submicroscopic infectious agent that replicates only inside the living Cell (biology), cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are ...
causing the mosaic disease in
tobacco Tobacco is the common name of several plants in the genus '' Nicotiana'' of the family Solanaceae, and the general term for any product prepared from the cured leaves of these plants. More than 70 species of tobacco are known, but the ...
plants led to the isolation of a nucleoprotein which displayed
tobacco mosaic virus Tobacco mosaic virus (TMV) is a positive-sense single-stranded RNA virus species in the genus '' Tobamovirus'' that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteris ...
activity. Stanley was elected to the
American Philosophical Society The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publicat ...
in 1940 and the United States
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
in 1941. He was awarded a ¼ share in the Nobel Prize in Chemistry for 1946. In 1949, he was elected to the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
. His other notable awards included the Rosenburger Medal, Alder Prize, Scott Award, the Golden Plate Award of the American Academy of Achievement and the AMA Scientific Achievement Award. He was also awarded
honorary degree An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or '' ad hon ...
s by many universities both American and foreign, including
Harvard Harvard University is a private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher lear ...
, Yale, Princeton and the
University of Paris The University of Paris (), known Metonymy, metonymically as the Sorbonne (), was the leading university in Paris, France, from 1150 to 1970, except for 1793–1806 during the French Revolution. Emerging around 1150 as a corporation associated wit ...
. Most of the conclusions Stanley had presented in his Nobel-winning research were soon shown to be incorrect (in particular, that the crystals of mosaic virus he had isolated were pure protein, and assembled by autocatalysis).


Personal life

Stanley married Marian Staples (1905–1984) in 1929 and had three daughters (Marjorie, Dorothy and Janet) and a son (Wendell Meredith Junior). Stanley Hall at UC Berkeley (now Stanley Biosciences and Bioengineering Facility) and Stanley Hall at Earlham College are named in his honor. His daughter, Marjorie, married Robert Albo, physician to the
Golden State Warriors The Golden State Warriors are an American professional basketball team based in San Francisco. The Warriors compete in the National Basketball Association (NBA) as a member of the Pacific Division of the Western Conference. Founded in 1946 i ...
basketball team as well as the
Oakland Raiders The Oakland Raiders were a professional American football team based in Oakland, California, from its founding in 1960 to 1981, and again from 1995 to 2019 before Oakland Raiders relocation to Las Vegas, relocating to the Las Vegas metropolitan ...
football team. He died in
Salamanca Salamanca () is a Municipality of Spain, municipality and city in Spain, capital of the Province of Salamanca, province of the same name, located in the autonomous community of Castile and León. It is located in the Campo Charro comarca, in the ...
, Spain on June 15, 1971.


References


External links

* including the Nobel Lecture on December 12, 1946 ''The Isolation and Properties of Crystalline Tobacco Mosaic Virus''
Wendell Meredith Stanley and the birth of biochemistry
at UC Berkeley
Guide to the Wendell M. Stanley Papers
at The Bancroft Library * {{DEFAULTSORT:Stanley, Wendell Meredith 1904 births 1971 deaths 20th-century American biochemists American Nobel laureates Earlham College alumni Nobel laureates in Chemistry People from Richmond, Indiana University of California, Berkeley faculty University of Illinois Urbana-Champaign alumni American virologists Members of the United States National Academy of Sciences Proceedings of the National Academy of Sciences of the United States of America editors Members of the American Philosophical Society Recipients of Franklin Medal