Fatty acid transport proteins (FATPs, SLC27, SLC27A) are a family of
trans-membrane transport proteins, which allow and enhance the uptake of long chain fatty acids into cells. This subfamily is part of the
solute carrier protein family. Within humans this family contains six very homologous proteins, which are expressed in all tissues of the body which use fatty acids:
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SLC27A1
Long-chain fatty acid transport protein 1 (FATP1) is a protein that in humans is encoded by the ''SLC27A1'' gene.
Structure
The ''SLC27A1'' gene is located on the 19th chromosome, with its specific location being 19p13.11. The gene contains 1 ...
(FATP1) Long-chain fatty acid transport protein 1
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SLC27A2
Long-chain fatty acid transport protein 2 is an enzyme that in humans is encoded by the ''SLC27A2'' gene.
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specifici ...
(FATP2) Very long-chain acyl-CoA synthetase
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SLC27A3
Long-chain fatty acid transport protein 3 is a protein that in humans is encoded by the ''SLC27A3'' gene.
In melanocytic cells SLC27A3 gene expression may be regulated by MITF.
See also
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* Solute carrier family
The solute carrier (SLC) group ...
(FATP3) Solute carrier family 27 member 3
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SLC27A4 (FATP4) Long-chain fatty acid transport protein 4
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SLC27A5
Bile acyl-CoA synthetase is an enzyme that in humans is encoded by the ''SLC27A5'' gene.
The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase ( VLCS). It is capable of activating very long-chain fatty-acids cont ...
(FATP5) Bile acyl-CoA synthetase
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SLC27A6 (FATP6) Long-chain fatty acid transport protein 6
References
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Protein families
Transport proteins