Tubulointerstitial nephritis and uveitis (TINU) is a rare medical condition in which there is
uveitis
Uveitis () is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and ...
(inflammation of the
uvea
The uvea (; derived from meaning "grape"), also called the uveal layer, uveal coat, uveal tract, vascular tunic or vascular layer, is the pigmented middle layer of the three concentric layers that make up an eye, precisely between the inne ...
in the eye) together with
tubulointerstitial nephritis (inflammation of the tubules inside the kidney).
Symptoms and signs
Uveitis may cause pain of the affected eye together with changes in vision. It may be accompanied by
nonspecific systemic symptoms such as fever, involuntary weight loss, fatigue, loss of appetite, abdominal pain, and joint pains.
Laboratory diagnosis
We can see increased eosinophils under microscope after biopsy.
Management
History
It was first described in 1975.
References
External links
{{Medical resources
, DiseasesDB =
, ICD10 = {{ICD10, Xxx.x
, ICD9 = {{ICD9, xxx
, ICDO =
, OMIM = 607665
, MedlinePlus =
, MeSH = C536922
, GeneReviewsNBK =
, GeneReviewsName =
, Orphanet = 91500
Kidney diseases
Disorders of iris and ciliary body
Rare diseases