Ticks
Ticks (order Ixodida) are parasitic arachnids that are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, species, and "fullness". Ticks are external parasites, living by ...
are insects known for attaching to and sucking
blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in th ...
from land-dwelling animals (specifically
vertebrates
Vertebrates () comprise all animal taxa within the subphylum Vertebrata () ( chordates with backbones), including all mammals, birds, reptiles, amphibians, and fish. Vertebrates represent the overwhelming majority of the phylum Chordata, wi ...
).
Ticks fall under the category of '
arthropod
Arthropods (, (gen. ποδός)) are invertebrate animals with an exoskeleton, a Segmentation (biology), segmented body, and paired jointed appendages. Arthropods form the phylum Arthropoda. They are distinguished by their jointed limbs and Arth ...
', and while they are often thought of in the context of
disease transmission, they are also known to cause direct harm to hosts through bites,
toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849 ...
release, and infestation. Infestation can cause symptoms ranging from mild to severe and may even cause death.
Hosts can include any number of vertebrates, though humans and livestock are more likely to be the interest of researchers.
Overview
There are two main categories of
tick
Ticks (order Ixodida) are parasitic arachnids that are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, species, and "fullness". Ticks are external parasites, living by ...
; soft ticks (''family
Argasidae
The Argasidae are the family of soft ticks, one of the three families of ticks. The family contains 193 species, although the composition of the genera is less certain, and more study is needed before the genera can become stable. The currentl ...
'') and hard ticks (family
Ixodidae
The Ixodidae are the family of hard ticks or scale ticks, one of the three families of ticks, consisting of over 700 species. They are known as 'hard ticks' because they have a scutum or hard shield, which the other major family of ticks, the 'so ...
).
A third tick family named
Nuttalliellidae also exists, though is less commonly discussed.
The primary distinction between soft and hard ticks is the amount of time they stay attached to their host. Soft ticks remain attached on the order of a couple hours and may take multiple blood meals from the same host. Hard ticks on the other hand tend to stay on attached for several days to weeks, feeding continuously.
The ticks that cause transmit
Lyme disease
Lyme disease, also known as Lyme borreliosis, is a vector-borne disease caused by the '' Borrelia'' bacterium, which is spread by ticks in the genus '' Ixodes''. The most common sign of infection is an expanding red rash, known as erythema ...
are hard ticks.
Ticks often have a preferred host, but may still attach to a different host when called for. Their preferred host may change depending on the tick's stage of development (eg
larval
A larva (; plural larvae ) is a distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle.
T ...
vs adult) and the host may or may not carry the transmittable
pathogen
In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a ger ...
.
An example of these concepts can be found in the
Deer Tick, known to transmit Lyme Disease to humans in the US. The larval stage of development takes place in a small mouse. This mouse also carries the bacterium that causes Lyme Disease. The adult Deer Tick attaches to its namesake, but the deer does not carry the bacterium. Humans are not the preferred natural host, but the adult ticks, containing the
bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were am ...
known to cause
Lyme disease
Lyme disease, also known as Lyme borreliosis, is a vector-borne disease caused by the '' Borrelia'' bacterium, which is spread by ticks in the genus '' Ixodes''. The most common sign of infection is an expanding red rash, known as erythema ...
, can attach to humans and allow for transmission of the bacterium.
Ticks are found around the world, with suggestions that
climate change
In common usage, climate change describes global warming—the ongoing increase in global average temperature—and its effects on Earth's climate system. Climate change in a broader sense also includes previous long-term changes to ...
and
globalization
Globalization, or globalisation (English in the Commonwealth of Nations, Commonwealth English; American and British English spelling differences#-ise, -ize (-isation, -ization), see spelling differences), is the process of foreign relation ...
of travel and commerce may be broadening their scope of residence.
Ticks use various tactics to reach their target host. Sometimes they employ a crawl-like movement to move towards their host. Other times they may perch along blades of
grass
Poaceae () or Gramineae () is a large and nearly ubiquitous family of monocotyledonous flowering plants commonly known as grasses. It includes the cereal grasses, bamboos and the grasses of natural grassland and species cultivated in law ...
or other vegetation, ready to move aboard animals as they brush by. After attachment, ticks gain access to a hosts
blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in th ...
supply via use of sharp projections from their mouth known as
chelicerae
The chelicerae () are the mouthparts of the subphylum Chelicerata, an arthropod group that includes arachnids, horseshoe crabs, and sea spiders. Commonly referred to as " jaws", chelicerae may be shaped as either articulated fangs, or simila ...
.
Under normal
physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemic ...
conditions, animals would form clots and prevent excess bleeding after damage from something like
chelicerae
The chelicerae () are the mouthparts of the subphylum Chelicerata, an arthropod group that includes arachnids, horseshoe crabs, and sea spiders. Commonly referred to as " jaws", chelicerae may be shaped as either articulated fangs, or simila ...
. Ticks account for this by secreting compounds in their
saliva that prevent normal healing and promote
bleeding
Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, vag ...
.
Disease state
Ticks can cause
disease
A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...
states unrelated to their ability to transmit pathogens such as
bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were am ...
and viruses.
Symptoms range from mild local irritation at the site of attachment all the way to death.
Local reactions can usually be seen within 24–48 hours of attachment and can be associated with swelling, itchiness, and pain.
Ticks can attach to most surfaces of the body and may even find residence within cavities such as the
ear.
More widespread reactions can occur, potentially leading to hives across the body, severe discomfort, and in some cases anaphylaxis (extreme
allergic reaction
Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derm ...
that can affect airways and
breathing
Breathing (or ventilation) is the process of moving air into and from the lungs to facilitate gas exchange with the internal environment, mostly to flush out carbon dioxide and bring in oxygen.
All aerobic creatures need oxygen for cell ...
).
In some cases, parts of the tick head can remain lodged at the site of attachment, resulting in more chronic
symptoms
Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition. A sign for example may be a higher or lower temperature than normal, raised or lowered blood pressure or an abnormality showi ...
and greater levels of swelling and tissue damage.
Serious
skin
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation.
Other cuticle, animal coverings, such as the arthropod exoskeleton, have diffe ...
infections such as
cellulitis
Cellulitis is usually a bacterial infection involving the inner layers of the skin. It specifically affects the dermis and subcutaneous fat. Signs and symptoms include an area of redness which increases in size over a few days. The borders of ...
can set in due to the tissue damage from tick attachment.
In rare cases, ticks
infestation can result in
paralysis
Paralysis (also known as plegia) is a loss of motor function in one or more muscles. Paralysis can also be accompanied by a loss of feeling (sensory loss) in the affected area if there is sensory damage. In the United States, roughly 1 in 5 ...
, a loss of motor function that can be debilitating and may even result in death.
Prevention
Preventing tick infestation is an important global effort. It is estimated that the worldwide cost associated with controlling tick levels and tick borne
disease
A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...
is as high as 13.9 to 18.7 million US dollars.
There are multiple ways to approach the issue of how to prevent tick infestation. For many years, the main way in which humans thought to control tick infestation was by the use of
pesticides
Pesticides are substances that are meant to pest control, control pest (organism), pests. This includes herbicide, insecticide, nematicide, molluscicide, piscicide, avicide, rodenticide, bactericide, insect repellent, animal repellent, microb ...
against ticks, called
acaricide
Acaricides are pesticides that kill members of the arachnid subclass ''Acari'', which includes ticks and mites.
Acaricides are used both in medicine and agriculture, although the desired selective toxicity differs between the two fields.
Termin ...
s.
This has been especially important in the context of ticks that infested
cattle
Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus '' Bos''. Adult females are referred to as cows and adult ...
.
But, these acaricides are often considered
toxic
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a subs ...
, expensive, and decreasingly effective.
Much as
bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were am ...
can
become resistant to
antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy, ...
, Ticks can gain resistance to acaricides, rendering them effective at preventing infestation. Studies suggest that
vaccination
Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating ...
may be an effective, less environmentally impactful, and less expensive way to prevent tick infestation.
A vaccine for humans to prevent
tick-borne encephalitis
Tick-borne encephalitis (TBE) is a viral infectious disease involving the central nervous system. The disease most often manifests as meningitis, encephalitis or meningoencephalitis. Myelitis and spinal paralysis also occurs. In about one thi ...
was approved by the
CDC in 2021 for use in the US.
Though, this is not stated to prevent infestation itself, but rather a specific
disease
A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...
related to infestation.
Some of the best preventive measures for humans to avoid infestation, outside of using pesticidal bug sprays, include avoidance, appropriate clothes, and
skin checks after potential tick encounters.
Jobs or hobbies that involve outdoor activities are shown to increase the risk of infestation, and as such, avoidance can be as simple as not
hiking
Hiking is a long, vigorous walk, usually on trails or footpaths in the countryside. Walking for pleasure developed in Europe during the eighteenth century.AMATO, JOSEPH A. "Mind over Foot: Romantic Walking and Rambling." In ''On Foot: A His ...
in or visiting areas known to be home to lots of ticks.
Clothes that cover exposed skin can help limit tick attachment but should not be a substitute for thorough skin and hair checks following a hike in known tick-infested regions.
If someone comes in contact with a tick, they should remove it from their
skin
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation.
Other cuticle, animal coverings, such as the arthropod exoskeleton, have diffe ...
, wash the area (
soap
Soap is a salt of a fatty acid used in a variety of cleansing and lubricating products. In a domestic setting, soaps are surfactants usually used for washing, bathing, and other types of housekeeping. In industrial settings, soaps are used ...
,
water
Water (chemical formula ) is an inorganic, transparent, tasteless, odorless, and nearly colorless chemical substance, which is the main constituent of Earth's hydrosphere and the fluids of all known living organisms (in which it acts as ...
, and an
antiseptic
An antiseptic (from Greek ἀντί ''anti'', "against" and σηπτικός ''sēptikos'', "putrefactive") is an antimicrobial substance or compound that is applied to living tissue/skin to reduce the possibility of infection, sepsis, or putre ...
), and preserve the tick in alcohol.
If symptoms develop, saving the tick will be important for identification. Home remedies (such as
vaseline
Vaseline ()Also pronounced with the main stress on the last syllable . is an American brand of petroleum jelly-based products owned by transnational company Unilever. Products include plain petroleum jelly and a selection of skin creams, soa ...
or
matches) have been used in the past, but are not currently recommended.
Tick-borne diseases
While ticks are most notable in the public view as the insects responsible for transmitting
Lyme disease
Lyme disease, also known as Lyme borreliosis, is a vector-borne disease caused by the '' Borrelia'' bacterium, which is spread by ticks in the genus '' Ixodes''. The most common sign of infection is an expanding red rash, known as erythema ...
, they carry and transmit a wide variety of other
pathogens
In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a ger ...
as well.
The bacterium that causes Lyme is ''
Borrelia burgdorferi
''Borrelia burgdorferi'' is a bacterial species of the spirochete class in the genus '' Borrelia'', and is one of the causative agents of Lyme disease in humans. Along with a few similar genospecies, some of which also cause Lyme disease, it ...
'', a
spirochete
A spirochaete () or spirochete is a member of the phylum Spirochaetota (), (synonym Spirochaetes) which contains distinctive diderm (double-membrane) gram-negative bacteria, most of which have long, helically coiled (corkscrew-shaped or s ...
.
A number of other bacteria are
transmitted by ticks, such as ''
Babesia
''Babesia'', also called ''Nuttallia'', is an apicomplexan parasite that infects red blood cells and is transmitted by ticks. Originally discovered by the Romanian bacteriologist Victor Babeș in 1888, over 100 species of ''Babesia'' have since ...
'' (very important in the context of cattle), ''
Ehrlichia
''Ehrlichia'' is a genus of Rickettsiales bacteria that are transmitted to vertebrates by ticks. These bacteria cause the disease ehrlichiosis, which is considered zoonotic, because the main reservoirs for the disease are animals.
''Ehrlichia' ...
'' (causes
ehrlichiosis
Ehrlichiosis is a tick-borne
bacterial infection, caused by bacteria of the family Anaplasmataceae, genera ''Ehrlichia'' and '' Anaplasma''. These obligate intracellular bacteria infect and kill white blood cells.
The average reported annual i ...
), ''
Anaplasma'' (causes
anaplasmosis
Anaplasmosis is a tick-borne disease affecting ruminants, dogs, and horses, and is caused by '' Anaplasma'' bacteria. Anaplasmosis is an infectious but not contagious disease. Anaplasmosis can be transmitted through mechanical and biological vecto ...
), ''
Rickettsia
''Rickettsia'' is a genus of nonmotile, gram-negative, nonspore-forming, highly pleomorphic bacteria that may occur in the forms of cocci (0.1 μm in diameter), bacilli (1–4 μm long), or threads (up to about 10 μm long). The term "ricke ...
'' (causes
Rocky Mountain Spotted Fever
Rocky Mountain spotted fever (RMSF) is a bacterial disease spread by ticks. It typically begins with a fever and headache, which is followed a few days later with the development of a rash. The rash is generally made up of small spots of bleedin ...
), and many others.
These bacterial infections]often cause well-described
rashes
A rash is a change of the human skin which affects its color, appearance, or texture.
A rash may be localized in one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, chapped, dry, cr ...
, such as the
bullseye rash of Lyme disease, or the spotted rash of
Rickettsiosis
A rickettsiosis is a disease caused by intracellular bacteria.
Cause
Rickettsioses can be divided into a spotted fever group (SPG) and typhus group (TG).
In the past, rickettsioses were considered to be caused by species of Rickettsia. However ...
.
Symptoms are variable during these infections, ranging from
self-limited to very severe disease.
Lyme disease, for example, is known to have potentially severe complications involving the heart, immune system, and neurological systems.
Non-
bacterial
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
pathogens transmitted by ticks are also common.
Viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells
Cell most often refers to:
* Cell (biology), the functional basic unit of life
Cell may also refer to:
Locations
* Monastic cell, a small room ...
transmitted by
arthropods
Arthropods (, (gen. ποδός)) are invertebrate animals with an exoskeleton, a segmented body, and paired jointed appendages. Arthropods form the phylum Arthropoda. They are distinguished by their jointed limbs and cuticle made of chitin, oft ...
such as ticks are an emerging field of study.
Commonly mentioned viruses include
phleboviruses
''Phlebovirus'' is one of twenty genera of the family ''Phenuiviridae'' in the order ''Bunyavirales''. The genus contains 66 species. It derives its name from Phlebotominae, the vectors of member species '' Naples phlebovirus'', which is said to ...
,
Heartland virus, and Bourbon viruses. Symptoms may include
hemorrhagic fever
Viral hemorrhagic fevers (VHFs) are a diverse group of animal and human illnesses in which fever and hemorrhage are caused by a viral infection. VHFs may be caused by five distinct families of RNA viruses: the families '' Filoviridae'', '' ...
(elevated body temperature involving bleeding from various parts of the body) and
thrombocytopenia
Thrombocytopenia is a condition characterized by abnormally low levels of platelets, also known as thrombocytes, in the blood. It is the most common coagulation disorder among intensive care patients and is seen in a fifth of medical patients a ...
(low levels of
platelets
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby i ...
in the body—an important component of
blood clotting
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanism ...
—deficiency results in worse bleeding).
Ticks can also transmit
parasitic infection, separate from
viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells
Cell most often refers to:
* Cell (biology), the functional basic unit of life
Cell may also refer to:
Locations
* Monastic cell, a small room ...
or
bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were am ...
, and are often found to have
co-infection with multiple types of
pathogen
In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a ger ...
.
There is some evidence that ''
Ixodes ricinus
''Ixodes ricinus'', the castor bean tick, is a chiefly European species of hard-bodied tick. It may reach a length of when engorged with a blood meal, and can transmit both bacterial and viral pathogens such as the causative agents of Lyme dis ...
'' infected with ''
Borrelia burgdorferi
''Borrelia burgdorferi'' is a bacterial species of the spirochete class in the genus '' Borrelia'', and is one of the causative agents of Lyme disease in humans. Along with a few similar genospecies, some of which also cause Lyme disease, it ...
'' may become more efficient at infestation.
References
External links
{{Pediculosis, acariasis and other infestations
Parasitic infestations, stings, and bites of the skin
Tick-borne diseases
Arthropod infestations