Tang Feifan (; July 23, 1897 – September 30, 1958) was a Chinese
medical
Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
microbiologist
A microbiologist (from Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of microscopic organisms such as bacteria, algae, fungi, and some types of par ...
best known for culturing the
''Chlamydia trachomatis'' agent in the yolk sacs of eggs.
Tang was persecuted during the "Pulling Out Bourgeois White Flag Movement" and committed suicide in 1958.
Biography
Early life
Tang was born Tang Ruizhao () in Tangjiaping Village of
Liling
Liling () is a county-level city and the 12th most populous county-level division in Hunan Province, China; it is under the administration of the prefecture-level city of Zhuzhou. Located on the middle eastern margin of the province, the city i ...
,
Hunan
Hunan is an inland Provinces of China, province in Central China. Located in the middle reaches of the Yangtze watershed, it borders the Administrative divisions of China, province-level divisions of Hubei to the north, Jiangxi to the east, Gu ...
, on July 23, 1897, to a relatively poor gentry family, during the
Qing Empire
The Qing dynasty ( ), officially the Great Qing, was a Manchu-led Dynasties of China, imperial dynasty of China and an early modern empire in East Asia. The last imperial dynasty in Chinese history, the Qing dynasty was preceded by the ...
.
He was the second of three children. He had a younger brother, Tang Qiufan ().
His father Tang Luquan () taught at a family friend He Zhongshan's () old-style private school, in which Tang Feifan studied poetry, history, philosophy, mathematics, and natural science. His son,
He Jian, became Tang Feifan's close friend.
"Learning from the West with its advanced science and technology;Invigorating the Chinese nation", Tang had often heard the hometown folks talk about reform and revolution in his childhood. When China was often called the "
sick man of Asia
The phrase "Sick man of Asia" (), or "Sick man of East Asia" () first referred to Qing China in the late 19th and early 20th centuries which, experiencing internal divisions and social upheaval at the time, was taken advantage of by the great powe ...
", Tang determined to study medicine science.
Education
At the age of twelve, he attended Chengnan School in Changsha, capital of Hunan province.
After graduating from the
Xiangya Medical College (now part of
Central South University) in 1921, he earned his doctoral degree in medical science from
Yale University
Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...
.
He went back to China in 1921 and that year studied, then taught at
Peking Union Medical College
Peking Union Medical College, also as Chinese Academy of Medical Sciences, is a national public medical sciences research institution in Dongcheng, Beijing, Dongcheng, Beijing, China. Originally founded in 1906, it is affiliated with the Nationa ...
.
In 1925 he went to the United States again to study
bacteriology
Bacteriology is the branch and specialty of biology that studies the Morphology (biology), morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the iden ...
under Professor
Hans Zinsser at
Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
.
He returned to China in 1929 and in the meantime became professor at Medical School of
National Central University
National Central University (; abbreviated NCU; ) is a public research university based in Taiwan. It was founded in 1902 in Nanjing; initially located in Miaoli after moving to Taiwan, it relocated to Zhongli in 1962 and developed into a com ...
.
In 1935 he was recruited as a researcher at the British National Institute for Medical Research, a position in which he remained until 1937.
Second Sino-Japanese War

After the outbreak of the
Second Sino-Japanese War
The Second Sino-Japanese War was fought between the Republic of China (1912–1949), Republic of China and the Empire of Japan between 1937 and 1945, following a period of war localized to Manchuria that started in 1931. It is considered part ...
in 1938, he founded the Central Epidemic Prevention Laboratory in
Kunming
Kunming is the capital and largest city of the province of Yunnan in China. The political, economic, communications and cultural centre of the province, Kunming is also the seat of the provincial government. During World War II, Kunming was a Ch ...
, capital of
southwest China
Southwestern China () is a region in the People's Republic of China. It consists of five provincial administrative regions, namely Chongqing, Sichuan, Guizhou, Yunnan, and Xizang.
Geography
Southwestern China is a rugged and mountainous region, ...
's
Yunnan
Yunnan; is an inland Provinces of China, province in Southwestern China. The province spans approximately and has a population of 47.2 million (as of 2020). The capital of the province is Kunming. The province borders the Chinese provinces ...
province, and served as its director.
He made China's first batch of
penicillin
Penicillins (P, PCN or PEN) are a group of beta-lactam antibiotic, β-lactam antibiotics originally obtained from ''Penicillium'' Mold (fungus), moulds, principally ''Penicillium chrysogenum, P. chrysogenum'' and ''Penicillium rubens, P. ru ...
and serum with his team for the soldiers at the front.
After war he established China's first antibiotic research and
penicillin
Penicillins (P, PCN or PEN) are a group of beta-lactam antibiotic, β-lactam antibiotics originally obtained from ''Penicillium'' Mold (fungus), moulds, principally ''Penicillium chrysogenum, P. chrysogenum'' and ''Penicillium rubens, P. ru ...
production workshop, as well as normal
BCG vaccine
The Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is common, one dose is recom ...
laboratory.
In 1947 he paid a fact-finding visit to the
United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotlan ...
, attended the 4th World Conference of
International Union of Microbiological Societies
The International Union of Microbiological Societies (IUMS), founded in 1927 as the International Society of Microbiology, is one of 40 member unions and associations of the International Science Council (ISC), and was formerly under ISC's pred ...
(IUMS) in the
Kingdom of Denmark
The Danish Realm, officially the Kingdom of Denmark, or simply Denmark, is a sovereign state consisting of a collection of constituent territories united by the Constitution of Denmark, Constitutional Act, which applies to the entire territor ...
, and became its standing committee.
People's Republic era
After the establishment of the Communist State, Tang successively served as director of Institute of Biological Products of the Ministry of Health, director of
Chinese Medical Association
In China, the practice of medicine is a mixture of government, charitable, and private institutions, while many people rely on traditional medicine. Until reforms in the late twentieth and early twenty-first century, physicians were quasi-governm ...
, and director general of
Chinese Society for Microbiology.
In 1950 he joined the newly created
National Institute for the Control of Pharmaceutical and Biological Products, working as its director.
During his time in office, he directed to develop China's first biological products specification - ''Verification Regulation of Biological Products'' ().
That same year, a terrible
plague hit the whole
north China
North China () is a list of regions of China, geographical region of the People's Republic of China, consisting of five province-level divisions of China, provincial-level administrative divisions, namely the direct-administered municipalities ...
, he developed China's own
yellow fever vaccine
Yellow fever vaccine is a vaccine that protects against yellow fever. Yellow fever is a viral infection that occurs in Africa and South America. Most people begin to develop immunity within ten days of vaccination and are 99% protected withi ...
.
In the mid-1950s, he first cultured the
''Chlamydia trachomatis'' agent in the yolk sacs of eggs.
In 1958, the "Pulling Out Bourgeois White Flag Movement" () broke out.
Tang was denounced and labeled as "capitalist academic authority", "scum of the nation", "a faithful running dog for the Kuomintang reactionaries", "American spy", "International spy", "a large white flag on the socialist positions", "ride on the backs of the people", "pseudo scientist", "sell the interests of his own country".
Because of the unbearable insult he killed himself on September 30, 1958.
In 1978, the Communist Party rehabilitated many victims who suffered
political persecution
Political repression is the act of a state entity controlling a citizenry by force for political reasons, particularly for the purpose of restricting or preventing the citizenry's ability to take part in the political life of a society, thereby ...
or died in the mass socialism political movements except Tang Feifan. In June 1979, the
Ministry of Health held a memorial service for him.
In 1981, the International Organization Against Trachoma (IOAT) bestowed its gold medal upon him.
He was held in high esteem by British sinologist
Joseph Needham
Noel Joseph Terence Montgomery Needham (; 9 December 1900 – 24 March 1995) was a British biochemist, historian of science and sinologist known for his scientific research and writing on the history of Chinese science and technology, initia ...
.
On 20 November 1992,
China Post
China Post, officially the China Post Group Corporation, is the national postal service corporation of the China, People's Republic of China. It is incorporated as a state-owned enterprise.
China Post shares its office with the sub-ministry- ...
issued a stamp commemorating Tang Feifan as part of the third set of its "Modern Chinese Scientists" stamp series (serial number 1992-19). 55 million copies were printed.
Personal life
In 1925, Tang married He Lian (), daughter of
He Jian, a warlord and
governor of Hunan province.
See also
* ''
Chlamydia trachomatis
''Chlamydia trachomatis'' () is a Gram-negative, Anaerobic organism, anaerobic bacterium responsible for Chlamydia infection, chlamydia and trachoma. ''C. trachomatis'' exists in two forms, an extracellular infectious elementary body (EB) and an ...
''
*
Hundred Flowers Campaign
*
Anti-Rightist Movement
The Anti-Rightist Campaign () in the People's Republic of China, which lasted from 1957 to roughly 1959, was a political campaign to purge alleged " Rightists" within the Chinese Communist Party (CCP) and the country as a whole. The campaign wa ...
*
Cultural Revolution
The Cultural Revolution, formally known as the Great Proletarian Cultural Revolution, was a Social movement, sociopolitical movement in the China, People's Republic of China (PRC). It was launched by Mao Zedong in 1966 and lasted until his de ...
References
External links
{{DEFAULTSORT:Tang, Feifan
1897 births
1958 suicides
1958 deaths
Chinese bacteriologists
Biologists from Hunan
Central South University alumni
Chinese microbiologists
Harvard University alumni
Members of the Chinese Academy of Sciences
Peking Union Medical College alumni
People from Zhuzhou
Suicides in the People's Republic of China
Yale School of Medicine alumni