THC methylcarbonate (Δ9-THC-methylcarbonate) is a semi-synthetic derivative of
tetrahydrocannabinol
Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. It is the principal psychoactive constituent of ''Cannabis'' and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) de ...
, first reported as a
designer drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ...
in August 2024 when it was identified in a seized shipment by customs in Sweden. Coincidentally, it was the 1000th new psychoactive substance identified by the EU Early Warning System on New Psychoactive Substances, first established in 1997.
Related THC carbonates and carbamates have been described as THC
prodrug
A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be ...
s in the patent literature.
See also
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Cod-THC
Cod-THC (Codeine Δ9-tetrahydrocannabinol carbonate) is a synthetic codrug formed by linking tetrahydrocannabinol with codeine via a carbonate bridge. It is well absorbed orally and shows superior analgesic effects in animal studies compared to a ...
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THC-O-acetate
THC-O-acetate (THC acetate ester, O-acetyl-THC, THC-O, AcO-THC) is the acetate ester of THC. The term ''THC-O-acetate'' and its variations are commonly used for two types of the substance, dependent on which cannabinoid it is synthesized from. ...
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THC hemisuccinate
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THC morpholinylbutyrate
References
Cannabinoids
Oxygen heterocycles
Heterocyclic compounds with 3 rings
Carbonate esters
Methyl esters
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