In September 2021, Synthetic Genomics Inc. (SGI), a private company located in
La Jolla, California, changed its name to Viridos. The company is focused on the field of
synthetic biology, especially harnessing photosynthesis with micro algae to create alternatives to fossil fuels. Viridos designs and builds
biological systems
A biological system is a complex network which connects several biologically relevant entities. Biological organization spans several scales and are determined based different structures depending on what the system is. Examples of biological syst ...
to address
global sustainability
Specific definitions of sustainability are difficult to agree on and have varied in the literature and over time. The concept of sustainability can be used to guide decisions at the global, national, and individual levels (e.g. sustainable livi ...
problems.
Synthetic biology is an interdisciplinary branch of
biology and engineering, combining fields such as
biotechnology,
evolutionary biology,
molecular biology,
systems biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological syst ...
,
biophysics,
computer engineering
Computer engineering (CoE or CpE) is a branch of electrical engineering and computer science that integrates several fields of computer science and electronic engineering required to develop computer hardware and software. Computer engineers ...
, and
genetic engineering
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including t ...
. Synthetic Genomics uses techniques such as
software engineering,
bioprocessing,
bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
, biodiscovery,
analytical chemistry,
fermentation
Fermentation is a metabolic process that produces chemical changes in organic substrates through the action of enzymes. In biochemistry, it is narrowly defined as the extraction of energy from carbohydrates in the absence of oxygen. In food ...
, cell
optimization, and
DNA synthesis to design and build biological systems. The company produces or performs research in the fields of sustainable
bio-fuels, insect resistant crops,
transplantable organs, targeted medicines, DNA synthesis
instruments
Instrument may refer to:
Science and technology
* Flight instruments, the devices used to measure the speed, altitude, and pertinent flight angles of various kinds of aircraft
* Laboratory equipment, the measuring tools used in a scientific l ...
as well as a number of biological
reagents.
Core markets
SGI mainly operates in three
end markets: research, bioproduction and applied products. The
research segment focuses on genomics solutions for academic and
commercial research organizations. The commercial products and services include
instrumentation,
reagents,
DNA synthesis services, and
bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
services and
software. In 2015, the company launched the BioXP 3200 system, a fully automated benchtop instrument that produces DNA fragments from many different sources for genomic data.
The company's efforts in bio-based production are intended to improve both existing production
hosts and develop entirely new synthetic production hosts with the goal of more efficient routes to
bioproducts.
SGI has a number of commercial as well as research and development stage programs across a variety of industries. Some of these
research partnerships include:
History
Synthetic Genomics was founded in the spring of 2005 by
J. Craig Venter
John Craig Venter (born October 14, 1946) is an American biotechnologist and businessman. He is known for leading one of the first draft sequences of the human genome and assembled the first team to transfect a cell with a synthetic chromosome. ...
, Nobel Laureate
Hamilton O. Smith
Hamilton Othanel Smith (born August 23, 1931) is an American microbiologist and Nobel laureate.
Smith was born on August 23, 1931, and graduated from University Laboratory High School of Urbana, Illinois. He attended the University of Illinois at ...
, Juan Enriquez, and David Kiernan. Venter (and Smith)'s previous company,
Celera Genomics, was a driving force in the race to sequence the
human genome.
The firm takes its name from the phrase
synthetic genomics
In September 2021, Synthetic Genomics Inc. (SGI), a private company located in La Jolla, California, changed its name to Viridos. The company is focused on the field of synthetic biology, especially harnessing photosynthesis with micro algae to ...
which is a scientific discipline of
synthetic biology related to the generation of organisms artificially using genetic material.
Many of SGI's collaborations have been with energy companies. In 2007, SGI worked with BP to commercialize microbial-based processes for increasing the conversion and recovery of subsurface hydrocarbons. In 2009, SGI received funding from
ExxonMobil
ExxonMobil Corporation (commonly shortened to Exxon) is an American multinational oil and gas corporation headquartered in Irving, Texas. It is the largest direct descendant of John D. Rockefeller's Standard Oil, and was formed on November 30, ...
to produce
biofuel
Biofuel is a fuel that is produced over a short time span from biomass, rather than by the very slow natural processes involved in the formation of fossil fuels, such as oil. According to the United States Energy Information Administration (E ...
s on an industrial-scale using recombinant
algae
Algae (; singular alga ) is an informal term for a large and diverse group of photosynthetic eukaryotic organisms. It is a polyphyletic grouping that includes species from multiple distinct clades. Included organisms range from unicellular mic ...
and other microorganisms. The company purchased an 81
acre
The acre is a unit of land area used in the imperial
Imperial is that which relates to an empire, emperor, or imperialism.
Imperial or The Imperial may also refer to:
Places
United States
* Imperial, California
* Imperial, Missouri
* Imp ...
site in
Southern California's
Imperial valley to produce
algae fuel for their collaboration with Exxon Mobil. They also signed a collaborative agreement with
New England Biolabs to Launch Gibson Assembly Master Mix Product for Synthetic and Molecular Biology Applications in 2012.
In 2010, Synthetic Genomics spun off a new subsidiary, Synthetic Genomics Vaccines Inc., to develop next generation
vaccines
In 2014 SGI expanded into the field of
organ transplantation with a collaborative agreement with
United Therapeutics valued at $50M and brought in Oliver Fetzer as
CEO
A chief executive officer (CEO), also known as a central executive officer (CEO), chief administrator officer (CAO) or just chief executive (CE), is one of a number of corporate executives charged with the management of an organization especially ...
.
Union Tribune Article
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References
External links
* {{Official website, http://www.syntheticgenomics.com/
Algae biomass producers
Biotechnology companies of the United States
Genetic engineering
Genomics companies
Synthetic biology