Sustanon 250
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Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone decanoate (TP/TPP/TiC/TD), also known as a Sustanon 250 (
Organon The ''Organon'' (, meaning "instrument, tool, organ") is the standard collection of Aristotle's six works on logical analysis and dialectic. The name ''Organon'' was given by Aristotle's followers, the Peripatetics, who maintained against the ...
), is an injectable
combination In mathematics, a combination is a selection of items from a set that has distinct members, such that the order of selection does not matter (unlike permutations). For example, given three fruits, say an apple, an orange and a pear, there are ...
medication Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to medical diagnosis, diagnose, cure, treat, or preventive medicine, prevent disease. Drug therapy (pharmaco ...
of four
testosterone ester This is a list of androgen esters, including esters (as well as ethers) of natural androgens like testosterone and dihydrotestosterone (DHT) and synthetic anabolic–androgenic steroids (AAS) like nandrolone (19-nortestosterone). Esters ...
s, all of which are
androgen An androgen (from Greek ''andr-'', the stem of the word meaning ) is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes ...
s/
anabolic steroid Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are a class of drugs that are structurally related to testosterone, the main male sex hormone, and produce effects by binding to the androgen receptor (AR). Anabolism, Anaboli ...
s.


Pharmacology

The four
testosterone ester This is a list of androgen esters, including esters (as well as ethers) of natural androgens like testosterone and dihydrotestosterone (DHT) and synthetic anabolic–androgenic steroids (AAS) like nandrolone (19-nortestosterone). Esters ...
s are as follows; * 30 mg
testosterone propionate Testosterone propionate, sold under the brand name Testoviron among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men. It has also been used to treat breast cance ...
* 60 mg
testosterone phenylpropionate Testosterone phenylpropionate (; TPP) (brand name Testolent), or testosterone phenpropionate, also known as testosterone hydrocinnamate, is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester – specifically, the C17β phenyl ...
* 60 mg
testosterone isocaproate Testosterone isocaproate (; TiCa), sold under the brand names Sustanon 100, Sustanon 250, and Omnadren 250, is an androgen and anabolic steroid medication and a testosterone ester This is a list of androgen esters, including esters (as well ...
* 100 mg testosterone decanoate Cumulatively, a 1 ml of the
oil solution An oil is any nonpolar chemical substance that is composed primarily of hydrocarbons and is hydrophobic (does not mix with water) and lipophilic (mixes with other oils). Oils are usually flammable and surface active. Most oils are unsaturat ...
contains exactly 250 mg of above mentioned
testosterone esters This is a list of androgen esters, including esters (as well as ethers) of natural product, natural androgens like testosterone (medication), testosterone and dihydrotestosterone (DHT) and synthetic compound, synthetic anabolic–androgenic stero ...
. This particular numerical value is clearly depicted in the name of the product, ''Sustanon 250''. They are provided as an
oil solution An oil is any nonpolar chemical substance that is composed primarily of hydrocarbons and is hydrophobic (does not mix with water) and lipophilic (mixes with other oils). Oils are usually flammable and surface active. Most oils are unsaturat ...
and are administered by
intramuscular injection Intramuscular injection, often abbreviated IM, is the medical injection, injection of a substance into a muscle. In medicine, it is one of several methods for parenteral, parenteral administration of medications. Intramuscular injection may be ...
. The different testosterone esters provide for different elimination half-lives in the body.
Esterification In chemistry, an ester is a compound derived from an acid (either organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group () of that acid is replaced by an organyl group (R). These compounds contain a distin ...
of
testosterone Testosterone is the primary male sex hormone and androgen in Male, males. In humans, testosterone plays a key role in the development of Male reproductive system, male reproductive tissues such as testicles and prostate, as well as promoting se ...
provides for a sustained but non-linear release of testosterone hormone from the injection depot into the circulation. Sustanon 100 is administered once every 2 weeks and Sustanon 250 is administered once every 3 to 4 weeks. Sustanon is the preferred method of testosterone replacement in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotlan ...
as detailed in the
British National Formulary The ''British National Formulary'' (BNF) is a United Kingdom (UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicin ...
. There was a brief shortage of Sustanon 250 during late 2011, due to shifting of manufacturing site, and a further shortage in mid-2012 due to manufacturing problems. This form of testosterone has long been a popular choice of
anabolic steroid Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are a class of drugs that are structurally related to testosterone, the main male sex hormone, and produce effects by binding to the androgen receptor (AR). Anabolism, Anaboli ...
among
bodybuilders Bodybuilding is the practice of progressive resistance exercise to build, control, and develop one's muscles via hypertrophy. An individual who engages in this activity is referred to as a bodybuilder. It is primarily undertaken for aesthetic ...
while bulking.


Synonyms/brands

* ''Durateston'' * ''Durandrone Forte'' * ''Sustanon prolongatum'' * ''Prarbolan''


Medical dosage


See also

* Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate * Testosterone propionate/testosterone phenylpropionate/testosterone isocaproate/testosterone caproate * List of combined sex-hormonal preparations § Androgens


References

{{Androgen receptor modulators Anabolic–androgenic steroids Androstanes Combined androgen formulations Drugs developed by Schering-Plough Drugs developed by Merck & Co. Testosterone esters Testosterone