Sup45p is the '' Saccharomyces cerevisiae'' (a yeast) eukaryotic translation termination factor. More specifically, it is the yeast eukaryotic release factor 1 (eRF1). Its job is to recognize stop

codons The genetic code is the set of rules used by living cells to translate information encoded within genetic material ( DNA or RNA sequences of nucleotide triplets, or codons) into proteins. Translation is accomplished by the ribosome, which links ...

in RNA and bind to them. It binds to the Sup35p protein and then takes on the shape of a tRNA molecule so that it can safety incorporate itself into the A site of the

Ribosome Ribosomes ( ) are macromolecular machines, found within all cells, that perform biological protein synthesis (mRNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA (mRNA) molecules to ...

to disruptits flow and "release" the protein and end translation.

Notes

Saccharomyces cerevisiae genes Protein biosynthesis {{Protein-stub