Stanley Dudrick
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Stanley John Dudrick (April 9, 1935 – January 18, 2020) was a surgeon who pioneered the use of
total parenteral nutrition Parenteral nutrition (PN), or intravenous feeding, is the feeding of nutritional products to a person intravenously, bypassing the usual process of eating and digestion. The products are made by pharmaceutical compounding entities or standard pha ...
(TPN).


Early life and education

Dudrick was born in
Nanticoke, Pennsylvania Nanticoke is a city in Luzerne County, Pennsylvania, United States. As of the 2020 census, the population was 10,628, making it the third largest city in Luzerne County. It occupies of land. Nanticoke is part of Northeastern Pennsylvania. The ...
, the grandson of Polish immigrants. His father was a coal miner and his mother a factory worker. At age seven he decided to become a doctor after seeing the care his mother received during a serious illness. He graduated
Franklin and Marshall College Franklin & Marshall College (F&M) is a private liberal arts college in Lancaster, Pennsylvania, United States. Founded in 1787 as Franklin College and later merged with Marshall College in 1853, it is one of the oldest colleges in the United St ...
in 1957. Graduating cum laude with a degree in biology with honors, he was awarded the Williamson Medal, the highest honor for student achievement. His first research project, done in college, was growing tomato plants and studying the effects of magnesium doses in the soil. In an interview, Dudrick stated:
The entire ethos of Franklin & Marshall College infected me and transformed me from a kid from the coal regions to an avid would-be scholar. They just imbued in me the importance of knowledge, that nothing was more precious than to gain knowledge and then to pass it on to others.
He received his medical degree from the
University of Pennsylvania School of Medicine The Perelman School of Medicine (commonly known as Penn Med) is the medical school of the University of Pennsylvania, a Private university, private, Ivy League research university located in Philadelphia. Founded in 1765, the Perelman School of M ...
.


Career

As a surgical resident at the University of Pennsylvania, Dudrick realized that post-surgical malnutrition was a poorly recognized cause of death in patients who could not eat or absorb nutrients. From 1964 to 1966, he worked with his mentor, Dr. Jonathon Rhoads, in developing TPN. After many hours in the lab at the swing balances, measuring the precise amount of each chemical required, he was able to keep beagles alive for months with TPN, by-passing their digestive systems. After showing the feasibility in lab animals, in 1967 he applied the technique to sick infants and then adults. Nutrition including carbohydrates, fats, proteins, vitamins and minerals were given directly into the circulatory system. In the subsequent decades Dudrick continued making significant contributions to the field. His contribution to field of medicine has been compared to
Joseph Lister Joseph Lister, 1st Baron Lister, (5 April 1827 – 10 February 1912) was a British surgeon, medical scientist, experimental pathologist and pioneer of aseptic, antiseptic surgery and preventive healthcare. Joseph Lister revolutionised the Sur ...
and
Alexander Fleming Sir Alexander Fleming (6 August 1881 – 11 March 1955) was a Scottish physician and microbiologist, best known for discovering the world's first broadly effective antibiotic substance, which he named penicillin. His discovery in 1928 of wha ...
, among others. The Geisinger School of Medicine wrote:
The number of lives of children that have been saved is estimated at over 10 million, and the benefit to adults with a range of conditions is no less substantial. TPN is a lifesaving mainstay of therapy for a great proportion of the most critically ill patients in hospitals worldwide and amounts to one of the most significant developments in the history of surgery.
Dudrick stayed at the University of Pennsylvania after finishing his residency, and became a full professor after only five years. He left in 1972 to become the founding chairman of the Department of Surgery at the
University of Texas Health Science Center at Houston The University of Texas Health Science Center at Houston (UTHealth Houston) is a public academic health science center in Houston, Texas, United States. It was created in 1972 by The University of Texas System Board of Regents. It is located ...
. He followed this up becoming chairman of surgery at the University of Pennsylvania, and then with professorships at
Yale Yale University is a private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the third-oldest institution of higher education in the United States, and one of the nine colonial colleges ch ...
and Geisinger medical schools. In 1975, Dudrick founded the American Society for Parenteral and Enteral Nutrition (ASPEN) serving as the first society president. ASPEN currently has 6,500 members and is a leading organization focused on improving nutrition clinical care and research on clinical nutrition. Dudrick received over 100 national and international awards, including the
American Surgical Association The American Surgical Association is the oldest surgical organization in the United States. History It was founded in 1880. Their publication, ''Annals of Surgery'', was started in 1885. A collection of the association's papers are held at the Na ...
’s first Flance-Karl Award in 1997 for his seminal and lifetime scientific contributions to surgery; the
American College of Surgeons The American College of Surgeons (ACS) is a professional medical association for surgeons and surgical team members, founded in 1913. It claims more than 90,000 members in 144 countries. History The ACS was founded in 1913 as an outgrowth of ...
Jacobsen Innovation Award in 2005; named by
Medscape Medscape is a website providing access to medical information for clinicians and medical scientists; the organization also provides continuing education for physicians and other health professionals. It references medical journal articles, Con ...
in 2016 as one of the 50 most influential physicians in history; named a "Hero in Surgery" in 2014 by the
American College of Surgeons The American College of Surgeons (ACS) is a professional medical association for surgeons and surgical team members, founded in 1913. It claims more than 90,000 members in 144 countries. History The ACS was founded in 1913 as an outgrowth of ...
, one of four people to have this distinction at that time; the American Surgical Association's highest honor in 2009, the Medallion for Scientific Achievement. He served on the Franklin and Marshall Board of Trustees and was awarded an honorary doctorate from the college.


Personal

In medical school he married Theresa Keen, and had six children. Stanley Dudrick died on January 18, 2020, in
Eaton, New Hampshire Eaton is a town in Carroll County, New Hampshire, United States. The population was 405 at the 2020 census. Eaton includes the villages of Eaton Center and Snowville. History Eaton was incorporated in 1766 by colonial Governor Benning W ...
, due to complications of ailments including
kidney failure Kidney failure, also known as renal failure or end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney fa ...
.


References


External links

* {{DEFAULTSORT:Dudrick, Stanley 1935 births 2020 deaths People from Nanticoke, Pennsylvania American surgeons Perelman School of Medicine at the University of Pennsylvania alumni Franklin & Marshall College alumni University of Texas Health Science Center at Houston faculty Yale School of Medicine faculty Perelman School of Medicine at the University of Pennsylvania faculty People from Luzerne County, Pennsylvania American medical researchers American physicians Intensivists